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Neuroscience20 (Brain20, Spine20, and Mental20) Health Initiative: A Global Consortium Addressing the Human and Economic Burden of Brain, Spine, and Mental Disorders Through Neurotech Innovations and Policies Publisher Pubmed



Morris K1, 2 ; Nami M1, 3, 4, 60 ; Bolanos JF1, 2 ; Lobo MA1, 2 ; Sadrinaini M1, 2 ; Fiallos J1, 2 ; Sanchez GE1, 2 ; Bustos T1, 2 ; Chintam N1, 2 ; Amaya M1, 2 ; Strand SE1, 2 ; Mayukudore A1, 2 ; Sakibova I1, 2 ; Biso GMN1, 2 Show All Authors
Authors
  1. Morris K1, 2
  2. Nami M1, 3, 4, 60
  3. Bolanos JF1, 2
  4. Lobo MA1, 2
  5. Sadrinaini M1, 2
  6. Fiallos J1, 2
  7. Sanchez GE1, 2
  8. Bustos T1, 2
  9. Chintam N1, 2
  10. Amaya M1, 2
  11. Strand SE1, 2
  12. Mayukudore A1, 2
  13. Sakibova I1, 2
  14. Biso GMN1, 2
  15. Defilippis A1, 2
  16. Bravo D1, 2
  17. Tarhan N1, 4, 5
  18. Claussen C1, 6
  19. Mercado A1, 7
  20. Braun S8
  21. Yuge L1, 9, 10
  22. Okabe S11
  23. Taghizadehhesary F12
  24. Kotliar K13
  25. Sadowsky C14
  26. Chandra PS15
  27. Tripathi M16
  28. Katsaros V17, 18, 19
  29. Mehling B20, 61
  30. Noroozian M4, 21
  31. Abbasioun K4, 22
  32. Amirjamshidi A4, 22
  33. Hosseinzadeh GA4, 23
  34. Naraghi F4, 24
  35. Barzegar M4, 25
  36. Asadipooya AA4, 26, 27
  37. Sahabnegah S4, 28, 62
  38. Sadeghian S4, 29
  39. Fahnestock M30
  40. Dilbaz N5
  41. Hussain N1, 31
  42. Mari Z1, 32
  43. Thatcher RW1, 33, 34
  44. Sipple D1, 2, 6
  45. Sidhu K1, 2, 35, 36, 37
  46. Chopra D38
  47. Costa F39, 40
  48. Spena G41
  49. Berger T1, 42
  50. Zelinsky D1, 43
  51. Wheeler CJ1, 12
  52. Ashford JW1, 44
  53. Schulte R1, 31
  54. Nezami MA45
  55. Kloor H1, 46
  56. Filler A1, 2, 47
  57. Eliashiv DS1, 48
  58. Sinha D1
  59. Desalles AAF49, 50, 51
  60. Sadanand V1, 2
  61. Suchkov S34, 52
  62. Green K1, 2
  63. Metin B4, 5
  64. Hariri R1, 2, 53, 54
  65. Cormier J1, 55
  66. Yamamoto V1, 2, 56, 57
  67. Kateb B4, 31, 58, 59
Show Affiliations
Authors Affiliations
  1. 1. Society for Brain Mapping and Therapeutics, Los Angeles, CA, United States
  2. 2. Brain Mapping Foundation, Los Angeles, CA, United States
  3. 3. Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Iran
  4. 4. Middle East Brain + Initiative, Los Angeles, CA, United States
  5. 5. Department of Psychiatry, Faculty of Medicine, Uskudar University, Istanbul, Turkey
  6. 6. Fraunhofer-Institute for Translational Research and Pharmacology, Hamburg, Germany
  7. 7. Department of Neurosurgery, Hospital Military Regional Mendoza, Mendoza, Argentina
  8. 8. AFM-Telethon France, Paris, France
  9. 9. Division of Bio-Environment Adaptation Sciences, Graduate School of Biomedical Health Sciences, Hiroshima University, Hiroshima, Japan
  10. 10. Cell Therapy Venture Company, Space Bio-Laboratories, Hiroshima, Japan
  11. 11. Brain Medical Science Collaboration Division, RIKEN Center for Brain Science Institution and Department: Cellular Neurobiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
  12. 12. Social Science Research Institute, Tokai University, Tokyo, Shibuya City, Japan
  13. 13. Department of Biomedical Engineering, Aachen University of Applied Sciences, Aachen, Germany
  14. 14. International Center for Spinal Cord Injury, Kennedy Krieger Institute-Johns Hopkins School of Medicine, Baltimore, MD, United States
  15. 15. Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India
  16. 16. Department of Neurology, AIIMS, New Delhi, India
  17. 17. Department of Advanced Imaging Modalities, MRI Unit, General Anti-Cancer and Oncological Hospital of Athens 'St. Savvas', Athens, Greece
  18. 18. Departments of Neurosurgery and Neurology, National and Kapodistrian University of Athens, Athens, Greece
  19. 19. Department of Neuroradiology, University College of London, London, United Kingdom
  20. 20. T-Neuro Pharma, Inc., Albuquerque, NM, United States
  21. 21. Cognitive Neurology and Neuropsychiatry Division, Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran
  22. 22. Department of Neurosurgery, Tehran University of Medical Sciences, Tehran, Iran
  23. 23. National Brain Mapping Laboratory, Tehran, Iran
  24. 24. Iranian Society for Brain Mapping Therapeutics, Tehran, Iran
  25. 25. Medical Physics Department, Tehran University of Medical Sciences, Tehran, Iran
  26. 26. Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  27. 27. Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA, United States
  28. 28. Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  29. 29. Department of Pediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  30. 30. Lafayette Surgical Specialty Hospital, Lafayette, LA, United States
  31. 31. Loma Linda University, School of Medicine, Loma Linda, CA, United States
  32. 32. Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States
  33. 33. Applied Neuroscience Research Institute, St. Petersburg, FL, United States
  34. 34. Applied Neuroscience, Inc., St. Petersburg, Fl, United States
  35. 35. CK Cell Technologies Pty Ltd, Norwest, NSW, Australia
  36. 36. Faculty of Medicine, Centre for Healthy Brain Ageing, University of New South Wales, Sydney, NSW, Australia
  37. 37. Society for Brain Mapping and Therapeutics-Sydney, Sydney, NSW, Australia
  38. 38. The Chopra Foundation, Orlando, FL, United States
  39. 39. IRCCS Humanitas Research Hospital, Milan, Italy
  40. 40. Department of Biomedical Sciences, Humanitas University, Milan, Italy
  41. 41. Azienda Ospedaliera della Provincia di Lecco, Brescia, Italy
  42. 42. USC Department of Biomedical Engineering, Los Angeles, CA, United States
  43. 43. The Mind-Eye Institute, Northbrook, IL, United States
  44. 44. Department of Psychiatry Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada
  45. 45. Sahel Oncology LLC, Newport Beach, CA, United States
  46. 46. Beyond Imagination, Los Angeles, CA, United States
  47. 47. Institute for Nerve Medicine, Santa Monica, CA, United States
  48. 48. Department of Neurology, UCLA-David Geffen School of Medicine, Los Angeles, CA, United States
  49. 49. Department of Neurosurgery, UCLA David Geffen School of Medicine, Los Angeles, CA, United States
  50. 50. NeuroSapiens - Rede d'Or Sao Luiz, Sao Paulo, Brazil
  51. 51. Society for Brain Mapping and Therapeutics-Brazil, Sao Paulo, Brazil
  52. 52. Society for Brain Mapping and Therapeutics-Russia, Moscow, Russian Federation
  53. 53. Celularity Corporation, Warren, NJ, United States
  54. 54. Weill Cornell School of Medicine, Department of Neurosurgery, New York, NY, United States
  55. 55. Blue Horizon International, Hackensack, NJ, United States
  56. 56. USC Keck School of Medicine, The USC Caruso Department of Otolaryngology-Head and Neck Surgery, Los Angeles, CA, United States
  57. 57. USC-Norris Comprehensive Cancer Center, Los Angeles, CA, United States
  58. 58. National Center for Nanobioelectronics, Los Angeles, CA, United States
  59. 59. Brain Technology and Innovation Park, Los Angeles, CA, United States
  60. 60. Neuroscience Center, Instituto de Investigaciones Cientificas Servicios de Alta Tecnologia, City of Knowledge, Panama City, Panama
  61. 61. StemVax LLC, Chesterland, OH, United States
  62. 62. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran

Source: Journal of Alzheimer's Disease Published:2021


Abstract

Neurological disorders significantly impact the world's economy due to their often chronic and life-threatening nature afflicting individuals which, in turn, creates a global disease burden. The Group of Twenty (G20) member nations, which represent the largest economies globally, should come together to formulate a plan on how to overcome this burden. The Neuroscience-20 (N20) initiative of the Society for Brain Mapping and Therapeutics (SBMT) is at the vanguard of this global collaboration to comprehensively raise awareness about brain, spine, and mental disorders worldwide. This paper aims to provide a comprehensive review of the various brain initiatives worldwide and highlight the need for cooperation and recommend ways to bring down costs associated with the discovery and treatment of neurological disorders. Our systematic search revealed that the cost of neurological and psychiatric disorders to the world economy by 2030 is roughly $16T. The cost to the economy of the United States is $1.5T annually and growing given the impact of COVID-19. We also discovered there is a shortfall of effective collaboration between nations and a lack of resources in developing countries. Current statistical analyses on the cost of neurological disorders to the world economy strongly suggest that there is a great need for investment in neurotechnology and innovation or fast-tracking therapeutics and diagnostics to curb these costs. During the current COVID-19 pandemic, SBMT, through this paper, intends to showcase the importance of worldwide collaborations to reduce the population's economic and health burden, specifically regarding neurological/brain, spine, and mental disorders. © 2021 - IOS Press. All rights reserved.
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