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Curcumin in Tissue Engineering: A Traditional Remedy for Modern Medicine Publisher Pubmed



Ahangari N1 ; Kargozar S1 ; Ghayourmobarhan M1, 2, 3 ; Baino F4 ; Pasdar A1, 5 ; Sahebkar A6, 7 ; Ferns GAA9 ; Kim HW10, 11, 12 ; Mozafari M13, 14, 15
Authors

Source: BioFactors Published:2019


Abstract

Curcumin is the principal polyphenolic compound present in turmeric with broad applications in tissue engineering and regenerative medicine. It has some important inherent properties with the potential to facilitate tissue healing, including anti-inflammatory, anti-oxidant, and antibacterial activities. Therefore, curcumin has been used for the treatment of various damaged tissues, especially wound injuries. There are different forms of curcumin, among which nano-formulations are of a great importance in regenerative medicine. It is also important to design sophisticated delivery systems for controlled/localized delivery of curcumin to the target tissues and organs. Although there are many reports on the advantages of this compound, further research is required to fully explore its clinical usage. The review describes the physicochemical and biological properties of curcumin and the current state of the evidence on its applications in tissue engineering. © 2018 BioFactors, 45(2):135–151, 2019. © 2018 International Union of Biochemistry and Molecular Biology
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