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The Role of Dna Methylation in Cancer Publisher



Shahkarami S1, 2, 3 ; Zoghi S1, 4, 5, 6 ; Rezaei N7, 8, 9
Authors

Source: Cancer Immunology: A Translational Medicine Context# Second Edition Published:2020


Abstract

DNA methylation is a highly characterized epigenetic mechanism, which plays a fundamental role in epigenetic disorders such as cancers. A large number of DNA methylation analysis strategies are available for assessing the DNA methylation status in order to define unique DNA methylation features and employing them as beneficial biomarkers for diagnosis, prognosis, and residual disease detecting. Furthermore, cancer therapy approaches hold promise for effective interventions with respect to reversible nature of DNA methylation aberrations. © Springer Nature Switzerland AG 2020.
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