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The Global, Regional, and National Burden of Stomach Cancer in 195 Countries, 1990–2017: A Systematic Analysis for the Global Burden of Disease Study 2017 Publisher Pubmed



Etemadi A1, 19 ; Safiri S20, 22 ; Sepanlou SG7, 25 ; Ikuta K28, 30 ; Bisignano C30 ; Shakeri R7 ; Amani M7 ; Fitzmaurice C29, 30 ; Nixon MR30 ; Abbasi N33 ; Abolhassani H16, 34 ; Advani SM36, 37 ; Afarideh M9 ; Akinyemiju T39, 40 Show All Authors
Authors
  1. Etemadi A1, 19
  2. Safiri S20, 22
  3. Sepanlou SG7, 25
  4. Ikuta K28, 30
  5. Bisignano C30
  6. Shakeri R7
  7. Amani M7
  8. Fitzmaurice C29, 30
  9. Nixon MR30
  10. Abbasi N33
  11. Abolhassani H16, 34
  12. Advani SM36, 37
  13. Afarideh M9
  14. Akinyemiju T39, 40
  15. Alam T30
  16. Alikhani M41, 48
  17. Alipour V44, 50
  18. Allen CA30
  19. Almasihashiani A49
  20. Arabloo J45
  21. Assadi R51
  22. Atique S52, 53
  23. Awasthi A54, 55
  24. Bakhtiari A10
  25. Behzadifar M56
  26. Berhe K57
  27. Bhala N59, 60
  28. Bijani A62
  29. Bin Sayeed MS64, 65
  30. Bjorge T66, 67
  31. Borzi AM68
  32. Braithwaite D38
  33. Brenner H70
  34. Carreras G71
  35. Carvalho F72, 74
  36. Castanedaorjuela CA35, 76
  37. Castro F77
  38. Chu DT79
  39. Costa VM75
  40. Daryani A87
  41. Davitoiu DV88, 89, 130
  42. Demoz GT91, 92
  43. Demis AB95
  44. Denovagutierrez E96
  45. Dey S98
  46. Nasab MD24
  47. Djalalinia S99
  48. Emamian MH101
  49. Farahmand M18
  50. Fernandes JC102
  51. Fischer F103
  52. Foroutan M104
  53. Gad MM105, 106
  54. Gallus S69
  55. Gebremeskel GG58, 90
  56. Gedefew GA94, 108
  57. Ghasenikebria F111
  58. Gorini G113
  59. Hafezinejad N17, 116
  60. Hajmirzaian A6, 120
  61. Haro JM121, 123
  62. Harvey JD30
  63. Hasanzadeh A5, 124
  64. Hashemian M1, 125
  65. Hassen HY126, 127
  66. Hay SI27, 30
  67. Hidru HD27, 128
  68. Hostiuc M88, 130, 134
  69. Househ M136, 137
  70. Ilesanmi OS138
  71. Ilic MD139
  72. Innos K140
  73. Islami F141
  74. James SL30
  75. Jenabi E142
  76. Kalhor R146, 147
  77. Kamangar F8, 148
  78. Kasaeian A11, 12
  79. Kengne AP149, 150
  80. Khader YS151
  81. Khalilov R152
  82. Khan EA153
  83. Khan G154
  84. Khayamzadeh M117, 156
  85. Khazaeepool M81, 84
  86. Khazaei S143
  87. Khoja AT115, 157
  88. Shadmani FK158
  89. Kim YJ162
  90. Kocarnik JM30, 163
  91. Komaki H144, 164
  92. Koyanagi A122, 165
  93. Kumar V166
  94. Vecchia CL167
  95. Lopez AD31, 168
  96. Lunevicius R169, 170
  97. Manafi N46, 171
  98. Manda AL172
  99. Meheretu H93, 173
  100. Mengistu G107, 109
  101. Miazgowski B174
  102. Mir SM61, 112
  103. Mohammad KA176, 177
  104. Mezerji NMG145
  105. Mohammadian M178
  106. Mohammadianhafshejani A179
  107. Mohammadpourhodki R100
  108. Mohammed S182, 183
  109. Mohebi F13, 14
  110. Mokdad AH27, 30
  111. Monasta L184
  112. Moosazadeh M83
  113. Moossavi M185
  114. Moradi G186, 187
  115. Moradpour F187
  116. Moradzadeh R188
  117. Velasquez IM78
  118. Mosapour A61, 180
  119. Naderi M160
  120. Naik G189
  121. Najafi F159
  122. Nahvijou A3
  123. Negoi I131, 132
  124. Nikbakhsh R119, 192
  125. Nojomi M43, 47
  126. Olagunju AT194, 195
  127. Olagunju TO193
  128. Oren E32, 196
  129. Parsian H61
  130. Piccinelli C197
  131. Pourshams A7
  132. Poustchi H7
  133. Rabiee N198
  134. Radfar A199, 200
  135. Rafiei A80, 86
  136. Rahimi M23
  137. Rahmati M2
  138. Renzaho AMN201
  139. Rezaei N15, 202
  140. Ribeiro AI73
  141. Roshandel G7, 111
  142. Saad AM204
  143. Saadatagah S4
  144. Salimzadeh H7
  145. Samy AM203
  146. Sanabria J205, 206
  147. Milicevic MMS207
  148. Sarveazad A42
  149. Sawhney M209
  150. Shaahmadi F210
  151. Sekerija M211, 212
  152. Shaikh MA213
  153. Bmedsc AS85
  154. Siddappa Malleshappa SK214
  155. Singh JA190, 191
  156. Smarandache CG133, 135
  157. Soofi M161
  158. Tabuchi T215
  159. Tadesse DBB216, 217
  160. Tapak L218
  161. Tesfay BE129
  162. Traini E184
  163. Tran B219
  164. Tran KB220, 221
  165. Vacante M68
  166. Vahedianazimi A222
  167. Veisani Y223
  168. Vosoughi K47, 114
  169. Vujcic IS208
  170. Westerman R224
  171. Wondmieneh AB110, 225
  172. Xu R30
  173. Yaya S226
  174. Yazdifeyzabadi V227, 228
  175. Yousefi Z82, 155
  176. Yousefi B21, 23
  177. Moghadam TZ45, 230
  178. Zaki L181
  179. Zamani M63
  180. Zamanian M188
  181. Zandian H229, 230
  182. Zarghi A118
  183. Zhang ZJ231
  184. Naghavi M26, 30
  185. Malekzadeh R7, 25
  186. Sajadi P62, 97

Source: The Lancet Gastroenterology and Hepatology Published:2020


Abstract

Background: Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach cancer and the differential trends across various locations is essential for formulating effective preventive strategies. We report on the incidence, mortality, and disability-adjusted life-years (DALYs) due to stomach cancer in 195 countries and territories from 21 regions between 1990 and 2017. Methods: Estimates from GBD 2017 were used to analyse the incidence, mortality, and DALYs due to stomach cancer at the global, regional, and national levels. The rates were standardised to the GBD world population and reported per 100 000 population as age-standardised incidence rates, age-standardised death rates, and age-standardised DALY rates. All estimates were generated with 95% uncertainty intervals (UIs). Findings: In 2017, more than 1·22 million (95% UI 1·19–1·25) incident cases of stomach cancer occurred worldwide, and nearly 865 000 people (848 000–885 000) died of stomach cancer, contributing to 19·1 million (18·7–19·6) DALYs. The highest age-standardised incidence rates in 2017 were seen in the high-income Asia Pacific (29·5, 28·2–31·0 per 100 000 population) and east Asia (28·6, 27·3–30·0 per 100 000 population) regions, with nearly half of the global incident cases occurring in China. Compared with 1990, in 2017 more than 356 000 more incident cases of stomach cancer were estimated, leading to nearly 96 000 more deaths. Despite the increase in absolute numbers, the worldwide age-standardised rates of stomach cancer (incidence, deaths, and DALYs) have declined since 1990. The drop in the disease burden was associated with improved Socio-demographic Index. Globally, 38·2% (21·1–57·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24·5% (20·0–28·9) of the age-standardised DALYs were attributable to smoking in males. Interpretation: Our findings provide insight into the changing burden of stomach cancer, which is useful in planning local strategies and monitoring their progress. To this end, specific local strategies should be tailored to each country's risk factor profile. Beyond the current decline in age-standardised incidence and death rates, a decrease in the absolute number of cases and deaths will be possible if the burden in east Asia, where currently almost half of the incident cases and deaths occur, is further reduced. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
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