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Electrochemical-Based Biosensors: New Diagnosis Platforms for Cardiovascular Disease Publisher Pubmed



Yousefi F1 ; Movahedpour A2, 3 ; Shabaninejad Z4, 5 ; Ghasemi Y2, 5, 6 ; Rabbani S7 ; Sobnaninasab A8 ; Mohammadi S9, 10 ; Hajimoradi B11 ; Rezaei S12 ; Savardashtaki A2, 5 ; Mazoochi M13 ; Mirzaei H14
Authors
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Authors Affiliations
  1. 1. Department of Biological Sciences, Faculty of Genetics, Tarbiat Modares University, Tehran, Iran
  2. 2. Department of Medical Biotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
  3. 3. Student research committee, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Department of Biological Sciences, Faculty of Nanotechnology, Tarbiat Modares University, Tehran, Iran
  5. 5. Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  6. 6. Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran
  7. 7. Research Center for Advanced Technologies in Cardiovascular Medicine, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Social Determinants of Health (SDH) Research Center, Kashan University of Medical Sciences, Kashan, Iran
  9. 9. Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
  10. 10. Nano Drug Delivery Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
  11. 11. Department of Shohaday-e-Tajrish Hospital, Shahid Beheshti University of Medical, Sciences (SBMU), Tehran, Iran
  12. 12. Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  13. 13. Department of Cardiology, Cardiac Electrophysiology Center, Kashan University of Medical Sciences, Kashan, Iran
  14. 14. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran

Source: Current Medicinal Chemistry Published:2020


Abstract

One of the major reasons for mortality throughout the world is cardiovascular diseases. Therefore, bio-markers of cardiovascular disease are of high importance to diagnose and manage procedure. Detecting biomarkers provided a promising procedure in developing bio-sensors. Fast, selective, portable, accurate, inexpensive, and sensitive biomarker sensing instruments will be necessary for detecting and predicting diseases. One of the cardiac biomarkers may be ordered as C-reactive proteins, lipoprotein-linked phospho-lipase, troponin I or T, myoglobin, interleukin-6, interleukin-1, tumor necrosis factor alpha, LDL and myeloperoxidase. The biomarkers are applied to anticipate cardio-vascular illnesses. Initial diagnoses of these diseases are possible by several techniques; however, they are laborious and need costly apparatus. Current researches designed various bio-sensors for resolving the respective issues. Electrochemical instruments and the proposed bio-sensors are preferred over other methods due to its inexpensiveness, mobility, reliability, repeatability. The present review comprehensively dealt with detecting biomarkers of cardiovascular disease through electro-chemical techniques. © 2020 Bentham Science Publishers.
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