Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Peptide and Protein Vaccines for Cancer Publisher



Keshavarzfathi M1, 2, 3 ; Rezaei N3, 4, 5
Authors
Show Affiliations
Authors Affiliations
  1. 1. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  3. 3. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives Published:2019


Abstract

Tumor antigens are the basis of most cancer vaccine strategies and other types of specific cancer immunotherapy. They are targeted by application of various approaches, and using the peptides containing the epitope(s) of a tumor antigen benefits form an standard and easy method to evoke anticancer immunity. However, some drawbacks are attributed to this simple method, which limit its usage unless optimization is undertaken. In this chapter, peptide- and protein-based vaccines against many types of cancer will be reviewed. Results of the clinical trials, advantages and disadvantages, and some suggestions to optimize peptide-based vaccine toward its pervasive usage will be provided. © 2019 Nima Rezaei and Mahsa Keshavarz-Fathi Published by Elsevier Ltd. All rights reserved.
Related Docs
View other Related Docs
1. Peptide and Protein Vaccines for Cancer, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2018)
2. Candidate Cancers for Vaccination, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2019)
3. Candidate Cancers for Vaccination, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2018)
4. Chimeric Antigen Receptor T-Cell Therapy for Melanoma, Expert Review of Clinical Immunology (2021)
5. Tumor Immunology, Clinical Immunology (2022)
6. Cancer Immunology, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2019)
7. Cancer Immunology, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2018)
8. Immunotherapy of Cancers Comes of Age, Expert Review of Clinical Immunology (2017)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (21)
Mazda Radmalekshahi (2)
Other Related Docs
9. Novel Treatment Opportunities for Sulfur Mustard-Related Cancers: Genetic and Epigenetic Perspectives, Archives of Toxicology (2017)
10. Shedding Light on the Side Effects of Immunotherapies Used for Leukemia: An Updated Review of the Literature, Expert Review of Anticancer Therapy (2023)
11. Concluding Remarks and Future Perspectives on Therapeutic Cancer Vaccines, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2019)
12. Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers, Immunological Investigations (2016)
13. Combination Therapy: Cancer Vaccines and Other Therapeutics, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2018)
14. Immunotherapy for Breast Cancer Treatment, Iranian Biomedical Journal (2021)
15. Potent Anti-Tumor Immune Response and Tumor Growth Inhibition Induced by Her2 Subdomain Fusion Protein in a Mouse Tumor Model, Journal of Cancer Research and Clinical Oncology (2023)
16. Concluding Remarks and Future Perspectives on Therapeutic Cancer Vaccines, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2018)
17. Combining Anti-Checkpoint Immunotherapies and Cancer Vaccines As a Novel Strategy in Oncological Therapy: A Review, Human Immunology (2025)
18. Immunology of Cutaneous Tumors and Immunotherapy for Melanoma, Cancer Immunology: Cancer Immunotherapy for Organ-Specific Tumors (2015)
19. Combination Therapy, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2019)
20. Obstacles in the Development of Therapeutic Cancer Vaccines, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2018)
21. Vaccines, Adjuvants, and Delivery Systems, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2019)
22. Development of Neoantigens: From Identification in Cancer Cells to Application in Cancer Vaccines, Expert Review of Vaccines (2022)
23. Self-Assembled Peptide/Polymer Hybrid Nanoplatform for Cancer Immunostimulating Therapies, Drug Delivery and Translational Research (2024)
24. Vaccines, Adjuvants, and Delivery Systems, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2018)
25. The Roles of Cd4+ T-Cells in Tumor Immunity, Cancer Immunology: A Translational Medicine Context# Second Edition (2020)
26. Obstacles in the Development of Therapeutic Cancer Vaccines, Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives (2019)
27. Self-Assembling Peptide Epitopes As Novel Platform for Anticancer Vaccination, Molecular Pharmaceutics (2017)
28. Cancer Vaccines for Triple-Negative Breast Cancer: A Systematic Review, Vaccines (2023)