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Sars-Cov-2-Related and Covid-19 Vaccine-Induced Thromboembolic Events: A Comparative Review Publisher Pubmed



Afshar ZM1 ; Barary M2, 3 ; Babazadeh A4 ; Hosseinzadeh R2 ; Alijanpour A5 ; Miri SR6 ; Sio TT7 ; Sullman MJM8, 9 ; Carsonchahhoud K10 ; Langer F11 ; Ebrahimpour S4
Authors
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Authors Affiliations
  1. 1. Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
  2. 2. Student Research Committee, Babol University of Medical Sciences, Babol, Iran
  3. 3. Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
  5. 5. Faculty of Medicine, Semmelweis University, Budapest, Hungary
  6. 6. Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran
  7. 7. Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, United States
  8. 8. Department of Social Sciences, University of Nicosia, Nicosia, Cyprus
  9. 9. Department of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus
  10. 10. Australian Centre for Precision Health, University of South Australia, Adelaide, Australia
  11. 11. Zentrum fur Onkologie, II. Medizinische Klinik und Poliklinik, Universitatsklinikum Eppendorf, Hamburg, Germany

Source: Reviews in Medical Virology Published:2022


Abstract

Since the start of the pandemic, thrombotic events have been a well-known and severe complication associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Nevertheless, the initiation of vaccination programs brought another rare yet highly fatal thrombotic event, vaccine-induced immune thrombotic thrombocytopaenia, which has caused extensive debate regarding the safety of vaccines. This review defines the thromboembolic events following infection and vaccination, identifies their risk factors, describes their pathophysiology, and discusses their management, treatment, and prevention. © 2022 John Wiley & Sons Ltd.
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