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A Luminescence Nanosensor for Ornidazole Detection Using Graphene Quantum Dots Entrapped in Silica Molecular Imprinted Polymer Publisher Pubmed



Mehrzadsamarin M1 ; Faridbod F2 ; Ganjali MR2, 3
Authors
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Authors Affiliations
  1. 1. School of Chemistry, Alborz Campus, University of Tehran, Tehran, Iran
  2. 2. Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  3. 3. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy Published:2019


Abstract

A luminescence nanosensor has been developed for analysis of Ornidazole in biological samples using graphene-quantum-dot-embedded silica molecular imprinted polymer (GQD-SMIP) as a selective probe for this analyte. The GQD-SMIP was found to possess a strong fluorescent emission at 450 nm upon excitation at 365 nm. This emission was found to linearly quench in the presence of Ornidazole in a concentration range of 0.75 to 30 μM. A detection limit of 0.24 μM was reached using the probe and the sensor was successfully used in the determination of the analyte in plasma samples. © 2018 Elsevier B.V.