Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Recent Advances on Akermanite Calcium-Silicate Ceramic for Biomedical Applications Publisher



Zadehnajar P1 ; Mirmusavi MH2 ; Soleymani Eil Bakhtiari S3 ; Bakhsheshirad HR3 ; Karbasi S4 ; Ramakrishna S5 ; Berto F6
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Biomaterials, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran
  2. 2. Department of Materials Engineering, Isfahan University of Technology, Isfahan, Iran
  3. 3. Advanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran
  4. 4. Biomaterials and Tissue Engineering Department, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department of Mechanical Engineering, National University of Singapore, Singapore, Singapore
  6. 6. Department of Mechanical and Industrial Engineering, Norwegian University of Science and Technology, Trondheim, Norway

Source: International Journal of Applied Ceramic Technology Published:2021


Abstract

Owing to great biocompatibility and high capacity of apatite formation, bioceramics, especially calcium silicate-based compounds, were extensively employed in orthopedic and dental uses concerning biomedical applications. Lately, akermanite (AK; Ca2MgSi2O7), as a bioceramic containing Ca-, Mg- and Si, has gained an increased level of attention because of its more tunable mechanical characteristics and degradation rate. All studies indicate that this magnesium incorporating Ca-silicate ceramic has a great capacity to use as a bone graft material to fulfill the necessity of bone reconstruction. Despite the rising interest in using these materials in biomedical fields, there has not yet been an extensive overview of this bioceramic property and its potential benefits. Thus, it has been speculated that this concept and the emergence of akermanite bioactive ceramics might lead to significant upcoming advancements in the field of bone tissue engineering (BTE). Definitely, the approach still requires additional advances to considerably better respond to the vital concerns regarding the clinical application. The review tackles the present research trends on akermanite ceramics for biomedical purposes such as bone scaffold, coating materials, bone cement, and treatment of osteoporotic bone defects, commencing with recent status and shifting to upcoming developments. © 2021 The American Ceramic Society
Related Docs
View other Related Docs
1. In Vivo Study of Nanostructured Akermanite/Peo Coating on Biodegradable Magnesium Alloy for Biomedical Applications, Journal of Biomedical Materials Research - Part A (2015)
2. Controlling the Degradation Rate of Bioactive Magnesium Implants by Electrophoretic Deposition of Akermanite Coating, Ceramics International (2014)
3. Biodegradable Magnesium Bone Implants Coated With a Novel Bioceramic Nanocomposite, Materials (2020)
4. Nanostructured Merwinite Bioceramic Coating on Mg Alloy Deposited by Electrophoretic Deposition, Ceramics International (2014)
5. Coating of Biodegradable Magnesium Alloy Bone Implants Using Nanostructured Diopside (Camgsi 2 O 6 ), Applied Surface Science (2014)
6. Nanobiomaterials in Periodontal Tissue Engineering, Nanobiomaterials in Hard Tissue Engineering: Applications of Nanobiomaterials (2016)
7. Improvement of Biodegradability, Bioactivity, Mechanical Integrity and Cytocompatibility Behavior of Biodegradable Mg Based Orthopedic Implants Using Nanostructured Bredigite (Ca7mgsi4o16) Bioceramic Coated Via Asd/Epd Technique, Annals of Biomedical Engineering (2014)
8. Combinatorial Fluorapatite-Based Scaffolds Substituted With Strontium, Magnesium and Silicon Ions for Mending Bone Defects, Materials Science and Engineering C (2021)
Experts (# of related papers)
View all Related Experts
Saeed Karbasi (23)
Mohammad Rafienia (21)
Other Related Docs
9. In Vivo Study of Nanostructured Diopside (Camgsi 2 O 6 ) Coating on Magnesium Alloy As Biodegradable Orthopedic Implants, Applied Surface Science (2014)
10. Surface Microstructure and in Vitro Analysis of Nanostructured Akermanite (Ca2mgsi2o7) Coating on Biodegradable Magnesium Alloy for Biomedical Applications, Colloids and Surfaces B: Biointerfaces (2014)
11. Electrophoretic Deposition of Bioactive Glass Nanopowders on Magnesium Based Alloy for Biomedical Applications, Ceramics International (2014)
12. Improvement of in Vitro Behavior of an Mg Alloy Using a Nanostructured Composite Bioceramic Coating, Journal of Materials Science: Materials in Medicine (2018)
13. In Vivo Biocompatibility of Mg Implants Surface Modified by Nanostructured Merwinite/Peo, Journal of Materials Science: Materials in Medicine (2015)
14. A 3D Nanostructured Calcium-Aluminum-Silicate Scaffold With Hierarchical Meso-Macroporosity for Bone Tissue Regeneration: Fabrication, Sintering Behavior, Surface Modification and in Vitro Studies, Journal of the European Ceramic Society (2021)
15. A Comparative Physico-Chemical Study of Bioactive Glass and Bone-Derived Hydroxyapatite, Ceramics International (2011)
16. Graphene Oxide-Encapsulated Baghdadite Nanocomposite Improved Physical, Mechanical, and Biological Properties of a Vancomycin-Loaded Pmma Bone Cement, Journal of Biomaterials Science, Polymer Edition (2024)
17. Porous Titanium Scaffold Coated Using Forsterite/Poly-3-Hydroxybutyrate Composite for Bone Tissue Engineering, Surface and Coatings Technology (2019)
18. A Novel Strategy for Fast and Facile Synthesis of Bioactive Bredigite Nanoparticles Using Microwave-Assisted Method, Journal of Materials Research and Technology (2023)
19. Mechanical and Cytotoxicity Evaluation of Nanostructured Hydroxyapatite-Bredigite Scaffolds for Bone Regeneration, Materials Science and Engineering C (2016)
20. Regenerative Influence of Nanostructured Bredigite (Ca7mgsi4o16)/Anodic Spark Coating on Biodegradable Az91 Magnesium Alloy Implants for Bone Healing, Materials Letters (2015)
21. Pepgen-P15 Delivery to Bone: A Novel 3D Printed Scaffold for Enhanced Bone Regeneration, Journal of Drug Delivery Science and Technology (2024)
22. Preparation and Biocompatibility Evaluation of Bioactive Glass-Forsterite Nanocomposite Powder for Oral Bone Defects Treatment Applications, Materials Science and Engineering C (2015)
23. Synthesis and Characterization of Bioactive Glass Coated Forsterite Scaffold for Tissue Engineering Applications, Journal of Alloys and Compounds (2017)
24. Surface Modification of Mg-Doped Fluoridated Hydroxyapatite Nanoparticles Using Bioactive Amino Acids As the Coupling Agent for Biomedical Applications, Ceramics International (2015)
25. The Effect of the Nano- Bioglass Reinforcement on Magnesium Based Composite, Journal of the Mechanical Behavior of Biomedical Materials (2019)
26. Nano-Biphasic Calcium Phosphate Ceramic for the Repair of Bone Defects, Journal of Craniofacial Surgery (2018)
27. Synthesis and Characterization of Nanosized Magnesium-Doped Fluorapatite Powder and Coating for Biomedical Application, Journal of Sol-Gel Science and Technology (2015)
28. Evaluation of Physical, Mechanical and Biological Properties of Β-Tri-Calcium Phosphate/Poly-3-Hydroxybutyrate Nano Composite Scaffold for Bone Tissue Engineering Application, Materials Technology (2021)
29. Controlling the Degradation Rate of Az91 Magnesium Alloy Via Sol-Gel Derived Nanostructured Hydroxyapatite Coating, Materials Science and Engineering C (2013)
30. The Influence of Bioglass Nanoparticles on the Biodegradation and Biocompatibility of Poly (3-Hydroxybutyrate) Scaffolds, International Journal of Artificial Organs (2012)
31. Magnesium/Nano-Hydroxyapatite Porous Biodegradable Composite for Biomedical Applications, Materials Research Express (2019)
32. Comparing Nanostructured Hydroxyapatite Coating on Az91 Alloy Samples Via Sol-Gel and Electrophoretic Deposition for Biomedical Applications, IEEE Transactions on Nanobioscience (2014)
33. Synthesis, Characterization, in Vitro Bioactivity and Biocompatibility Evaluation of Hydroxyapatite/Bredigite (Ca7mgsi4o16) Composite Nanoparticles, JOM (2016)
34. Fabrication of Elastin Additive on Polymethyl Methacrylate and Hydroxyapatite-Based Bioactive Bone Cement, Materials Chemistry and Physics (2022)
35. Preparation, Chemistry and Physical Properties of Bone-Derived Hydroxyapatite Particles Having a Negative Zeta Potential, Materials Chemistry and Physics (2012)
36. Preparation and Bioactivity Evaluation of Bone-Like Hydroxyapatite Nanopowder, Journal of Materials Processing Technology (2008)
37. Fabrication and Characterization of 3D-Printed Composite Scaffolds of Coral-Derived Hydroxyapatite Nanoparticles/Polycaprolactone/Gelatin Carrying Doxorubicin for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2024)
38. Comparative Evaluation of Hydroxyapatite and Nano-Bioglass in Two Forms of Conventional Micro-And Nano-Particles in Repairing Bone Defects (An Animal Study), Indian Journal of Dental Research (2015)
39. Effect of Calcium Silicate Nanoparticle on Surface Feature of Calcium Phosphates Hybrid Bio-Nanocomposite Using for Bone Substitute Application, Powder Technology (2020)
40. In Vivo Assessments of Bioabsorbable Az91 Magnesium Implants Coated With Nanostructured Fluoridated Hydroxyapatite by Mao/Epd Technique for Biomedical Applications, Materials Science and Engineering C (2015)
41. In Vivo and in Vitro Evaluation of Poly (Lactide-Co-Glycolide)/Bioactive Glass Nanocomposite Coating, Advanced Materials Research (2014)
42. Effect of Mg Content on the Bioactivity and Biocompatibility of Mg-Substituted Fluorapatite Nanopowders Fabricated Via Mechanical Activation, Materials Science and Engineering C (2016)
43. Calcitonin-Loaded Octamaleimic Acid–Silsesquioxane Nanoparticles in Hydrogel Scaffold Support Osteoinductivity in Bone Regeneration, Pharmaceutical Development and Technology (2021)
44. Natural Hydroxyapatite/Diopside Nanocomposite Scaffold for Bone Tissue Engineering Applications: Physical, Mechanical, Bioactivity and Biodegradation Evaluation, Materials Technology (2022)
45. Biodegradation Assessment of Nanostructured Fluoridated Hydroxyapatite Coatings on Biomedical Grade Magnesium Alloy, Ceramics International (2014)
46. In Vitro Studies of Polycaprolactone Nanofibrous Scaffolds Containing Novel Gehlenite Nanoparticles, Journal of Medical Signals and Sensors (2021)
47. Simultaneous Structural and Surface Modifications of Nanophase Hydroxyapatite for Improving Its Dissolution and Bioactivity, Ceramics International (2016)
48. Biodegradable Magnesium Alloy Coated by Fluoridated Hydroxyapatite Using Mao/Epd Technique, Surface Engineering (2014)
49. Novel Sol–Gel-Derived Hardystonite-Based Biomagnetic Nanoparticles for Hyperthermia Applications, Journal of Sol-Gel Science and Technology (2016)
50. Synthesis, Characterization and Bioactivity Evaluation of Nano-Structured Hydroxyapatite, WIT Transactions on Engineering Sciences (2009)