Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Porous Starch/Cellulose Nanofibers Composite Prepared by Salt Leaching Technique for Tissue Engineering Publisher



Nasrinasrabadi B1 ; Mehrasa M2 ; Rafienia M3 ; Bonakdar S4 ; Behzad T1 ; Gavanji S5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Chemical Engineering, Isfahan University of Technology, Isfahan 8415681167, Iran
  2. 2. Department of Biotechnology, Faculty of Advanced Sciences and Technologies, University of Isfahan, Isfahan 81746-73441, Iran
  3. 3. Biosensor Research Center, Isfahan University of Medical Sciences, 81744-176 Isfahan, Iran
  4. 4. National Cell Bank of Iran, Pasteur Institute of Iran, 1316943551 Tehran, Iran
  5. 5. Young Researchers Club, Khorasgan Branch, Islamic Azad University, Khorasgan, Isfahan, Iran

Source: Carbohydrate Polymers Published:2014


Abstract

Starch/cellulose nanofibers composites with proper porosity pore size, mechanical strength, and biodegradability for cartilage tissue engineering have been reported in this study. The porous thermoplastic starch-based composites were prepared by combining film casting, salt leaching, and freeze drying methods. The diameter of 70% nanofibers was in the range of 40-90 nm. All samples had interconnected porous morphology; however an increase in pore interconnectivity was observed when the sodium chloride ratio was increased in the salt leaching. Scaffolds with the total porogen content of 70 wt% exhibited adequate mechanical properties for cartilage tissue engineering applications. The water uptake ratio of nanocomposites was remarkably enhanced by adding 10% cellulose nanofibers. The scaffolds were partially destroyed due to low in vitro degradation rate after more than 20 weeks. Cultivation of isolated rabbit chondrocytes on the fabricated scaffold proved that the incorporation of nanofibers in starch structure improves cell attachment and proliferation. © 2014 Elsevier Ltd.
Related Docs
View other Related Docs
1. Electrospun Poly(Hydroxybutyrate)/Chitosan Blend Fibrous Scaffolds for Cartilage Tissue Engineering, Journal of Applied Polymer Science (2016)
2. Fabrication of Chitosan/Agarose Scaffolds Containing Extracellular Matrix for Tissue Engineering Applications, International Journal of Biological Macromolecules (2020)
3. Incorporation of Zeolite and Silica Nanoparticles Into Electrospun Pva/Collagen Nanofibrous Scaffolds: The Influence on the Physical, Chemical Properties and Cell Behavior, International Journal of Polymeric Materials and Polymeric Biomaterials (2016)
4. Evaluation of the Effects of Hyaluronic Acid on Poly (3-Hydroxybutyrate)/Chitosan/Carbon Nanotubes Electrospun Scaffold: Structure and Mechanical Properties, Polymer-Plastics Technology and Materials (2019)
5. Evaluation of the Effects of Glucosamine Sulfate on Poly(3- Hydroxybutyrate) -Chitosan/Carbon Nanotubes Electrospun Scaffold for Cartilage Tissue Engineering Applications, Polymer-Plastics Technology and Materials (2022)
6. Evaluation of the Effects of Β-Tricalcium Phosphate on Physical, Mechanical and Biological Properties of Poly (3-Hydroxybutyrate)/Chitosan Electrospun Scaffold for Cartilage Tissue Engineering Applications, Materials Technology (2019)
7. A Core-Shell Electrospun Scaffold of Polyhydroxybutyrate-Starch/Halloysite Nanotubes Containing Extracellular Matrix and Chitosan for Articular Cartilage Tissue Engineering Application, Journal of Polymers and the Environment (2023)
8. Evaluation of the Effects of Starch on Polyhydroxybutyrate Electrospun Scaffolds for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2021)
Experts (# of related papers)
View all Related Experts
Saeed Karbasi (89)
Mohammad Rafienia (49)
Other Related Docs
9. Electrospun Halloysite Nanotube Loaded Polyhydroxybutyrate-Starch Fibers for Cartilage Tissue Engineering, International Journal of Biological Macromolecules (2022)
10. Effects of Cartilage Acellular Solubilised Ecm on Physicomechanical and Biological Properties of Polycaprolactone/Fibrin Hybrid Scaffold Fabricated by 3D-Printing and Salt-Leaching Methods, Materials Technology (2022)
11. Casein Release and Characterization of Electrospun Nanofibres for Cartilage Tissue Engineering, Bulletin of Materials Science (2022)
12. Development of Electrospun Poly (Vinyl Alcohol)-Based Bionanocomposite Scaffolds for Bone Tissue Engineering, Journal of Biomedical Materials Research - Part A (2018)
13. Polycaprolactone-Chitosan/Multi-Walled Carbon Nanotube: A Highly Strengthened Electrospun Nanocomposite Scaffold for Cartilage Tissue Engineering, International Journal of Biological Macromolecules (2022)
14. Evaluation of the Effects of Chitosan Nanoparticles on Polyhydroxy Butyrate Electrospun Scaffolds for Cartilage Tissue Engineering Applications, International Journal of Biological Macromolecules (2023)
15. Fabrication and Characterization of Chitosan-Gelatin/Single-Walled Carbon Nanotubes Electrospun Composite Scaffolds for Cartilage Tissue Engineering Applications, Polymers for Advanced Technologies (2022)
16. Evaluation of Mechanical Properties and Cell Viability of Poly (3-Hydroxybutyrate)-Chitosan/Al2o3nanocomposite Scaffold for Cartilage Tissue Engineering, Journal of Medical Signals and Sensors (2019)
17. Biological Evaluation of the Effects of Hyaluronic Acid on Poly (3-Hydroxybutyrate) Based Electrospun Nanocomposite Scaffolds for Cartilage Tissue Engineering Application, Materials Technology (2020)
18. Characterization of Silk/Poly 3-Hydroxybutyrate-Chitosan-Multi-Walled Carbon Nanotube Micro-Nano Scaffold: A New Hybrid Scaffold for Tissue Engineering Applications, Journal of Medical Signals and Sensors (2018)
19. Incorporation of Mesoporous Silica Nanoparticles Into Random Electrospun Plga and Plga/Gelatin Nanofibrous Scaffolds Enhances Mechanical and Cell Proliferation Properties, Materials Science and Engineering C (2016)
20. Incorporation of Chitosan Nanoparticles Into Silk Fibroin-Based Porous Scaffolds: Chondrogenic Differentiation of Stem Cells, International Journal of Polymeric Materials and Polymeric Biomaterials (2016)
21. Polyhydroxybutyrate-Starch/Carbon Nanotube Electrospun Nanocomposite: A Highly Potential Scaffold for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2022)
22. Evaluation of the Effects of Cartilage Decellularized Ecm in Optimizing Phb-Chitosan-Hnt/Chitosan-Ecm Core-Shell Electrospun Scaffold: Physicochemical and Biological Properties, Biomaterials Advances (2025)
23. Chondrogenesis of Human Adipose-Derived Mesenchymal Stromal Cells on the [Devitalized Costal Cartilage Matrix/Poly(Vinyl Alcohol)/Fibrin] Hybrid Scaffolds, European Polymer Journal (2019)
24. Preparing Nanocomposite Fibrous Scaffolds of P3hb/Nha for Bone Tissue Engineering, 2010 17th Iranian Conference of Biomedical Engineering, ICBME 2010 - Proceedings (2010)
25. Cartilage Particles Can Promote Chondrogenesis of Adipose-Derived Stromal Cells on Poly(Ε-Caprolactone)/Fibrin Hybrid Constructs Prepared Via Sandwich Model, Journal of Biomimetics, Biomaterials and Biomedical Engineering (2020)
26. Evaluation of the Effects of Decellularized Extracellular Matrix Nanoparticles Incorporation on the Polyhydroxybutyrate/Nano Chitosan Electrospun Scaffold for Cartilage Tissue Engineering, International Journal of Biological Macromolecules (2024)
27. Effects of Decellularized Extracellular Matrix on Polyhydroxybutyrate Electrospun Scaffolds for Cartilage Tissue Engineering, Polymer-Plastics Technology and Materials (2023)
28. Effect of Cellulose Nanofibers on Polyhydroxybutyrate Electrospun Scaffold for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2022)
29. Evaluation of the Effects of Halloysite Nanotubes on Physical, Mechanical, and Biological Properties of Polyhydroxy Butyrate Electrospun Scaffold for Cartilage Tissue Engineering Applications, Journal of Polymers and the Environment (2024)
30. Electrospun Captopril-Loaded Pcl-Carbon Quantum Dots Nanocomposite Scaffold: Fabrication, Characterization, and in Vitro Studies, Polymers for Advanced Technologies (2020)
31. Mechanical Evaluation of Nhap Scaffold Coated With Poly-3-Hydroxybutyrate for Bone Tissue Engineering, Journal of Nanoscience and Nanotechnology (2013)
32. Electrospun Nanocomposite Scaffold Based on Polycaprolactone-Decellularized Umbilical Cord Wharton’S Jelly/Multi-Walled Carbon Nanotubes: A Biomimetic Substrate for Articular Cartilage Tissue Engineering, Journal of Polymers and the Environment (2023)
33. Silk Fibroin-Chondroitin Sulfate-Alginate Porous Scaffolds: Structural Properties and in Vitro Studies, Journal of Applied Polymer Science (2014)
34. Physicomechanical and Cellular Behavior of 3D Printed Polycaprolactone/Poly(Lactic-Co-Glycolic Acid) Scaffold Containing Polyhedral Oligomeric Silsesquioxane and Extracellular Matrix Nanoparticles for Cartilage Tissue Engineering, Polymers for Advanced Technologies (2022)
35. Potential of Novel Electrospun Core-Shell Structured Polyurethane/Starch (Hyaluronic Acid) Nanofibers for Skin Tissue Engineering: In Vitro and in Vivo Evaluation, International Journal of Biological Macromolecules (2020)
36. A Novel Nano-Composite Scaold for Cartilage Tissue Engineering, Scientia Iranica (2018)
37. A Ternary Nanocomposite Fibrous Scaffold Composed of Poly(Ε-Caprolactone)/Gelatin/Gehlenite (Ca2al2sio7): Physical, Chemical, and Biological Properties in Vitro, Polymers for Advanced Technologies (2021)
38. A Comparative Study of Articular Chondrocytes Metabolism on a Biodegradable Polyesterurethane Scaffold and Alginate in Different Oxygen Tension and Ph, IFMBE Proceedings (2009)
39. Does the Tissue Engineering Architecture of Poly(3-Hydroxybutyrate) Scaffold Affects Cell-Material Interactions?, Journal of Biomedical Materials Research - Part A (2012)
40. Characterization of Poly(Ε-Caprolactone)/Extracellular Matrix Nanofibers Composite Scaffold for Tissue Engineering, Journal of Isfahan Medical School (2019)
41. Chondrogenesis of Mesenchymal Stromal Cells on the 3D Printed Polycaprolactone/Fibrin/Decellular Cartilage Matrix Hybrid Scaffolds in the Presence of Piascledine, Journal of Biomaterials Science, Polymer Edition (2024)
42. Evaluation of the Effects of Decellularized Wharton Jelly Nanoparticles on Polyhydroxy Butyrate-Chitosan Electrospun Scaffolds for Cartilage Tissue Engineering Applications, Journal of Polymers and the Environment (2025)
43. A Comparison Between Cell Viability of Chondrocytes on a Biodegradable Polyester Urethane Scaffold and Alginate Beads in Different Oxygen Tension and Ph, Iranian Polymer Journal (English Edition) (2005)
44. Preparation of Fibrin/Poly Vinyl Alcohol Electrospun Nanofibers Scaffold for Tissue Engineering Applications, Journal of Isfahan Medical School (2016)
45. Preparation and Characterization of Poly Ε-Caprolactone-Gelatin/Multi-Walled Carbon Nanotubes Electrospun Scaffolds for Cartilage Tissue Engineering Applications, International Journal of Polymeric Materials and Polymeric Biomaterials (2020)
46. Incorporation of Nanohydroxyapatite and Vitamin D3 Into Electrospun Pcl/Gelatin Scaffolds: The Influence on the Physical and Chemical Properties and Cell Behavior for Bone Tissue Engineering, Polymers for Advanced Technologies (2018)
47. Effects of Multi-Wall Carbon Nanotubes on Structural and Mechanical Properties of Poly(3-Hydroxybutyrate)/Chitosan Electrospun Scaffolds for Cartilage Tissue Engineering, Bulletin of Materials Science (2017)
48. A Modular Approach to 3D-Printed Bilayer Composite Scaffolds for Osteochondral Tissue Engineering, Journal of Materials Science: Materials in Medicine (2024)
49. A New Approach to Fabrication of Cs/Bg/Cnt Nanocomposite Scaffold Towards Bone Tissue Engineering and Evaluation of Its Properties, Applied Surface Science (2015)
50. Evaluation of Structural, Mechanical, and Cellular Behavior of Electrospun Poly-3-Hydroxybutyrate Scaffolds Loaded With Glucosamine Sulfate to Develop Cartilage Tissue Engineering, International Journal of Polymeric Materials and Polymeric Biomaterials (2017)