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Cerebral Phaeohyphomycosis Due to Rhinocladiella Mackenziei in Persian Gulf Region: A Case and Review Publisher Pubmed



Mohammadi R1, 2 ; Mohammadi A1 ; Ashtari F3 ; Khorvash F4 ; Hakamifard A2, 5 ; Vaezi A6 ; Javidnia J6 ; Meis JF7, 8 ; Badali H9
Authors

Source: Mycoses Published:2018


Abstract

Cerebral phaeohyphomycosis is frequently a fatal disease caused by truly neurotropic dematiaceous fungi. Although rare, this infection occurs especially among immunocompetent patients, and the clinical symptoms are often misdiagnosed as a cerebral tumour or bacterial brain abscess. The appropriate diagnosis and therapy of cerebral infections by melanized fungi are very challenging if they are caused by mysterious fungi with unknown ecological niche. We reported the second case of cerebral phaeohyphomycosis due to Rhinocladiella mackenziei in Iran and the first culture-confirmed case. In this report, the differential diagnosis and histopathological findings are discussed and a review of the literature is provided. © 2017 Blackwell Verlag GmbH
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