Prenatal Nutrition Exposure Leading to Adult Obesity, Diabetes, and Hypertension Publisher



Miraghajani M^{1, 2} ; Salehi R³ ; Hossein H^{4, 5} Show Affiliations
Source: Nutrigenomics and Nutraceuticals: Clinical Relevance and Disease Prevention Published:2017

Abstract

Some metabolic disorders including obesity, diabetes, and hypertension are becoming the most common chronic health problem worldwide and represent the main cause of mortality and morbidity [1,2]. As the importance of diet in health and disease has been established, the newfield of “developmental origins of health and disease” discusses about epigenome programming during critical periods of early development following fetal nutrition exposure in pregnancy that permanently alters some metabolic status and organism’s physiology in which consequences are often observed much later in adults [3]. These epigenetic modifications involve heritable or nonheritable changes in gene expression during this critical period [4,5]. © 2018 by Taylor & Francis Group, LLC.