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Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Low, But Not High, Dose Triptolide Controls Neuroinflammation and Improves Behavioral Deficits in Toxic Model of Multiple Sclerosis by Dampening of Nf-Κb Activation and Acceleration of Intrinsic Myelin Repair

Parichehr Pasbakhsh

Parichehr Pasbakhsh

Professor of Anatomical Sciences

Department Anatomy

School of Medicine

Tehran University of Medical Sciences

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1. Metformin Therapy Attenuates Pro-Inflammatory Microglia by Inhibiting Nf-Κb in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis, Neurotoxicity Research (2021)

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3. Effect of the Csf1r Inhibitor Plx3397 on Remyelination of Corpus Callosum in a Cuprizone-Induced Demyelination Mouse Model, Journal of Cellular Biochemistry (2019)

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5. Regulatory Effect of Triiodothyronine on Brain Myelination and Astrogliosis After Cuprizone-Induced Demyelination in Mice, Metabolic Brain Disease (2016)

6. Intranasal Delivery of Sdf-1Α-Preconditioned Bone Marrow Mesenchymal Cells Improves Remyelination in the Cuprizone-Induced Mouse Model of Multiple Sclerosis, Cell Biology International (2020)

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1. Retraction Note To: Preconditioning With Melatonin Improves Therapeutic Outcomes of Bone Marrow-Derived Mesenchymal Stem Cells in Targeting Liver Fibrosis Induced by Ccl4 (Cell and Tissue Research, (2017), 369, 2, (303-312), 10.1007/S00441-017-2604-1), Cell and Tissue Research (2025)

2. Valproic Acid Preconditioning of Bone Marrow Mesenchymal Stem Cells Promotes Remyelination of the Corpus Callosum in a Cuprizone-Induced Demyelination Model, Biomedicine and Pharmacotherapy (2025)

3. Benefits of Bone Marrow Mesenchymal Stem Cells Compared to Their Conditioned Medium in Valproic Acid-Induced Autism in Rats, Molecular Biology Reports (2024)

4. Correction To: Calorie Restriction Promotes Remyelination in a Cuprizone-Induced Demyelination Mouse Model of Multiple Sclerosis (Metabolic Brain Disease, (2020), 35, 7, (1211-1224), 10.1007/S11011-020-00597-0), Metabolic Brain Disease (2024)

5. Microglia/Macrophage Polarization Regulates Spontaneous Remyelination in Intermittent Cuprizone Model of Demyelination, Biochemistry and Biophysics Reports (2024)

6. Correction To: Astrocyte Ablation Induced by La-Aminoadipate (L-Aaa) Potentiates Remyelination in a Cuprizone Demyelinating Mouse Model (Metabolic Brain Disease, (2019), 34, 2, (593-603), 10.1007/S11011-019-0385-9), Metabolic Brain Disease (2023)

7. Correction To: Combination Therapy of Mesenchymal Stem Cell Transplantation and Astrocyte Ablation Improve Remyelination in a Cuprizone‑Induced Demyelination Mouse Model (Molecular Neurobiology, (2022), 59, 12, (7278-7292), 10.1007/S12035-022-03036-6), Molecular Neurobiology (2023)

8. Effects of Calorie Restriction on Multiple Sclerosis: A Review of the Preclinical and Clinical Studies, Neurochemical Research (2023)

9. Combination Therapy of Mesenchymal Stem Cell Transplantation and Astrocyte Ablation Improve Remyelination in a Cuprizone-Induced Demyelination Mouse Model, Molecular Neurobiology (2022)

10. Glial Response to Intranasal Mesenchymal Stem Cells in Intermittent Cuprizone Model of Demyelination, Neurotoxicity Research (2022)

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12. Mesenchymal Stem Cells Ameliorate Cuprizone-Induced Demyelination by Targeting Oxidative Stress and Mitochondrial Dysfunction, Cellular and Molecular Neurobiology (2021)

13. Metformin Therapy Attenuates Pro-Inflammatory Microglia by Inhibiting Nf-Κb in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis, Neurotoxicity Research (2021)

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15. The Effect of Microglial Ablation and Mesenchymal Stem Cell Transplantation on a Cuprizone-Induced Demyelination Model, Journal of Cellular Physiology (2021)

16. Calorie Restriction Promotes Remyelination in a Cuprizone-Induced Demyelination Mouse Model of Multiple Sclerosis, Metabolic Brain Disease (2020)

17. Effects of Exogenous Melatonin on Mam Induced Lung Injury and Lung Development in Mice Offspring, Tanaffos (2020)

18. Intranasal Delivery of Sdf-1Α-Preconditioned Bone Marrow Mesenchymal Cells Improves Remyelination in the Cuprizone-Induced Mouse Model of Multiple Sclerosis, Cell Biology International (2020)

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21. Astrocyte Ablation Induced by La-Aminoadipate (L-Aaa) Potentiates Remyelination in a Cuprizone Demyelinating Mouse Model, Metabolic Brain Disease (2019)

22. Effect of the Csf1r Inhibitor Plx3397 on Remyelination of Corpus Callosum in a Cuprizone-Induced Demyelination Mouse Model, Journal of Cellular Biochemistry (2019)

23. Melatonin Preconditioning of Bone Marrow-Derived Mesenchymal Stem Cells Promotes Their Engraftment and Improves Renal Regeneration in a Rat Model of Chronic Kidney Disease, Journal of Molecular Histology (2019)

24. Oligoprotective Effect of Metformin Through the Ampk-Dependent on Restoration of Mitochondrial Hemostasis in the Cuprizone-Induced Multiple Sclerosis Model, Journal of Molecular Histology (2019)

25. Preconditioning With Sdf-1 Improves Therapeutic Outcomes of Bone Marrow-Derived Mesenchymal Stromal Cells in a Mouse Model of Stz-Induced Diabetes, Avicenna Journal of Medical Biotechnology (2019)

26. Embryonic Intraventricular Transplantation of Neural Stem Cells Augments Inflammation-Induced Prenatal Brain Injury, Journal of Chemical Neuroanatomy (2018)

27. Melatonin Pretreated Blastocysts Along With Calcitonin Administration Improved Implantation by Upregulation of Heparin Binding-Epidermal Growth Factor Expression in Murine Endometrium, Cell Journal (2018)

28. Microglia Polarization by Methylprednizolone Acetate Accelerates Cuprizone Induced Demyelination, Journal of Molecular Histology (2018)

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30. Therapeutic Effect of Perinatal Exogenous Melatonin on Behavioral and Histopathological Changes and Antioxidative Enzymes in Neonate Mouse Model of Cortical Malformation, International Journal of Developmental Neuroscience (2018)

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37. Effect of Human Recombinant Granulocyte Colony-Stimulating Factor on Rat Busulfan-Induced Testis Injury, Journal of Molecular Histology (2016)

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39. Melatonin Pretreatment Enhances the Homing of Bone Marrow-Derived Mesenchymal Stem Cells Following Transplantation in a Rat Model of Liver Fibrosis, Iranian Biomedical Journal (2016)

40. Regulatory Effect of Triiodothyronine on Brain Myelination and Astrogliosis After Cuprizone-Induced Demyelination in Mice, Metabolic Brain Disease (2016)

41. Therapeutic Value of Melatonin Post-Treatment on Ccl4-Induced Fibrotic Rat Liver, Canadian Journal of Physiology and Pharmacology (2016)

42. Do Pilea Microphylla Improve Sperm Dna Fragmentation and Sperm Parameters in Varicocelized Rats?, Acta medica Iranica (2015)

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