Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Cytotoxic Effects of Targeted Galactosylated Pluronic F127/Pluronicl122 Nano-Sized Micelles Loaded With Doxorubicin in Human Hepatocellular Carcinoma Cell Line
Jaber Emami Baferani
Jaber Emami Baferani

Professor of Pharmaceutics

Department of Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences

Pharmaceutical Sciences Research Center

Isfahan University of Medical Sciences

Related Documents
1. Synthesis and in Vitro Evaluation of Self-Assembling Biocompatible Heparin-Based Targeting Polymeric Micelles for Delivery of Doxorubicin to Leukemic Cells, Research in Pharmaceutical Sciences (2025)
2. In Vitro and in Vivo Evaluation of Novel Dtx-Loaded Multifunctional Heparin-Based Polymeric Micelles Targeting Folate Receptors and Endosomes, Recent Patents on Anti-Cancer Drug Discovery (2020)
3. Plga-Peg-Ra-Based Polymeric Micelles for Tumor Targeted Delivery of Irinotecan, Pharmaceutical Development and Technology (2018)
4. A Novel Mixed Polymeric Micelle for Co-Delivery of Paclitaxel and Retinoic Acid and Overcoming Multidrug Resistance: Synthesis, Characterization, Cytotoxicity, and Pharmacokinetic Evaluation, Drug Development and Industrial Pharmacy (2018)
5. Preparation and Characterization of an Injectable Thermosensitive Hydrogel for Simultaneous Delivery of Paclitaxel and Doxorubicin, Research in Pharmaceutical Sciences (2018)
6. In Vivo Pharmacokinetics, Biodistribution and Anti-Tumor Effect of Paclitaxel-Loaded Targeted Chitosan-Based Polymeric Micelle, Drug Delivery (2016)
7. Targeted Nanostructured Lipid Carriers for Delivery of Paclitaxel to Cancer Cells: Preparation, Characterization, and Cell Toxicity, Current Drug Delivery (2017)
8. Development and Optimization of Transferrin-Conjugated Nanostructured Lipid Carriers for Brain Delivery of Paclitaxel Using Box–Behnken Design, Pharmaceutical Development and Technology (2017)
9. An Injectable Thermosensitive Hydrogel/Nanomicelles Composite for Local Chemo-Immunotherapy in Mouse Model of Melanoma, Journal of Biomaterials Applications (2022)
10. Pegylated Multifunctional Ph-Responsive Targeted Polymeric Micelles for Ovarian Cancer Therapy: Synthesis, Characterization and Pharmacokinetic Study, International Journal of Polymeric Materials and Polymeric Biomaterials (2021)
11. Co-Delivery of Paclitaxel and Α-Tocopherol Succinate by Novel Chitosan-Based Polymeric Micelles for Improving Micellar Stability and Efficacious Combination Therapy, Drug Development and Industrial Pharmacy (2015)
12. Physicochemical, Pharmaceutical and Biological Approaches Toward Designing Optimized and Efficient Hydrophobically Modified Chitosan-Based Polymeric Micelles As a Nanocarrier System for Targeted Delivery of Anticancer Drugs, Journal of Drug Targeting (2013)
13. Development and in Vitro/In Vivo Evaluation of a Novel Targeted Polymeric Micelle for Delivery of Paclitaxel, International Journal of Biological Macromolecules (2015)
14. Preparation and Characterization of Spray-Dried Inhalable Powders Containing Polymeric Micelles for Pulmonary Delivery of Paclitaxel in Lung Cancer, Journal of Pharmacy and Pharmaceutical Sciences (2018)
15. Novel Ph-Triggered Biocompatible Polymeric Micelles Based on Heparin–Α-Tocopherol Conjugate for Intracellular Delivery of Docetaxel in Breast Cancer, Pharmaceutical Development and Technology (2020)
All Documents
1. Synthesis and in Vitro Evaluation of Self-Assembling Biocompatible Heparin-Based Targeting Polymeric Micelles for Delivery of Doxorubicin to Leukemic Cells, Research in Pharmaceutical Sciences (2025)
2. An Injectable Thermosensitive Hydrogel/Nanomicelles Composite for Local Chemo-Immunotherapy in Mouse Model of Melanoma, Journal of Biomaterials Applications (2022)
3. Development and Validation of a New Robust Rp-Hplc Method for Simultaneous Quantitation of Insulin and Pramlintide in Non-Invasive and Smart Glucose-Responsive Microparticles, Research in Pharmaceutical Sciences (2022)
4. Pulmonary Delivery of Docetaxel and Celecoxib by Plga Porous Microparticles for Their Synergistic Effects Against Lung Cancer, Anti-Cancer Agents in Medicinal Chemistry (2022)
5. In Vitro and in Vivo Evaluation of Two Hydroxychloroquine Tablet Formulations: Hplc Assay Development, Journal of Chromatographic Science (2021)
6. Pegylated Multifunctional Ph-Responsive Targeted Polymeric Micelles for Ovarian Cancer Therapy: Synthesis, Characterization and Pharmacokinetic Study, International Journal of Polymeric Materials and Polymeric Biomaterials (2021)
7. The Uniqueness of Albumin As a Carrier in Nanodrug Delivery, Molecular Pharmaceutics (2021)
8. Development of a Rp-Hplc Method for Analysis of Docetaxel in Tumor-Bearing Mice Plasma and Tissues Following Injection of Docetaxel-Loaded Ph Responsive Targeting Polymeric Micelles, Research in Pharmaceutical Sciences (2020)
9. In Vitro and in Vivo Evaluation of Novel Dtx-Loaded Multifunctional Heparin-Based Polymeric Micelles Targeting Folate Receptors and Endosomes, Recent Patents on Anti-Cancer Drug Discovery (2020)
10. Novel Ph-Triggered Biocompatible Polymeric Micelles Based on Heparin–Α-Tocopherol Conjugate for Intracellular Delivery of Docetaxel in Breast Cancer, Pharmaceutical Development and Technology (2020)
11. Simultaneous Determination of Docetaxel and Celecoxib in Porous Microparticles and Rat Plasma by Liquid-Liquid Extraction and Hplc With Uv Detection: In Vitro and in Vivo Validation and Application, Journal of Pharmacy and Pharmaceutical Sciences (2020)
12. Receptor Targeting Drug Delivery Strategies and Prospects in the Treatment of Rheumatoid Arthritis, Research in Pharmaceutical Sciences (2019)
13. Therapeutic Drug Monitoring of Vancomycin by Auc Τ -Mic Ratio in Patients With Chronic Kidney Disease, Research in Pharmaceutical Sciences (2019)
14. A Novel Mixed Polymeric Micelle for Co-Delivery of Paclitaxel and Retinoic Acid and Overcoming Multidrug Resistance: Synthesis, Characterization, Cytotoxicity, and Pharmacokinetic Evaluation, Drug Development and Industrial Pharmacy (2018)
15. Plga-Peg-Ra-Based Polymeric Micelles for Tumor Targeted Delivery of Irinotecan, Pharmaceutical Development and Technology (2018)
16. Preparation and Characterization of an Injectable Thermosensitive Hydrogel for Simultaneous Delivery of Paclitaxel and Doxorubicin, Research in Pharmaceutical Sciences (2018)
17. Preparation and Characterization of Spray-Dried Inhalable Powders Containing Polymeric Micelles for Pulmonary Delivery of Paclitaxel in Lung Cancer, Journal of Pharmacy and Pharmaceutical Sciences (2018)
18. Targeted Nanostructured Lipid Carrier for Brain Delivery of Artemisinin: Design, Preparation, Characterization, Optimization and Cell Toxicity, Journal of Pharmacy and Pharmaceutical Sciences (2018)
19. Development and Optimization of Transferrin-Conjugated Nanostructured Lipid Carriers for Brain Delivery of Paclitaxel Using Box–Behnken Design, Pharmaceutical Development and Technology (2017)
20. Targeted Nanostructured Lipid Carriers for Delivery of Paclitaxel to Cancer Cells: Preparation, Characterization, and Cell Toxicity, Current Drug Delivery (2017)
21. A Simple and Sensitive Hplc Method for Analysis of Imipramine in Human Plasma With Uv Detection and Liquid-Liquid Extraction: Application in Bioequivalence Studies, Research in Pharmaceutical Sciences (2016)
22. Design and in Vitro Evaluation of a Novel Controlled Onset Extendedrelease Delivery System of Metoprolol Tartrate, Research in Pharmaceutical Sciences (2016)
23. Effects of Probiotic Drop Containing Lactobacillus Rhamnosus, Bifidobacterium Infantis, and Lactobacillus Reuteri on Salivary Streptococcus Mutans and Lactobacillus Levels, Contemporary Clinical Dentistry (2016)
24. In Vivo Pharmacokinetics, Biodistribution and Anti-Tumor Effect of Paclitaxel-Loaded Targeted Chitosan-Based Polymeric Micelle, Drug Delivery (2016)
25. A Rapid and Sensitive Hplc Method for Quantitation of Paclitaxel in Biological Samples Using Liquid-Liquid Extraction and Uv Detection: Application to Pharmacokinetics and Tissues Distribution Study of Paclitaxel Loaded Targeted Polymeric Micelles in Tumor Bearing Mice, Journal of Pharmacy and Pharmaceutical Sciences (2015)
26. Co-Delivery of Paclitaxel and Α-Tocopherol Succinate by Novel Chitosan-Based Polymeric Micelles for Improving Micellar Stability and Efficacious Combination Therapy, Drug Development and Industrial Pharmacy (2015)
27. Development and in Vitro/In Vivo Evaluation of a Novel Targeted Polymeric Micelle for Delivery of Paclitaxel, International Journal of Biological Macromolecules (2015)
28. Formulation and Optimization of Celecoxib-Loaded Plga Nanoparticles by the Taguchi Design and Their in Vitro Cytotoxicity for Lung Cancer Therapy, Pharmaceutical Development and Technology (2015)
29. Formulation and Optimization of Solid Lipid Nanoparticle Formulation for Pulmonary Delivery of Budesonide Using Taguchi and Box-Behnken Design, Research in Pharmaceutical Sciences (2015)
30. Preparation, Characterization and Optimization of Glipizide Controlled Release Nanoparticles, Research in Pharmaceutical Sciences (2014)
31. Quantification of Pantoprazole by High Performance Liquid Chromatography (Hplc) Method: In Vitro and in Vivo Applications, Journal of Liquid Chromatography and Related Technologies (2014)
32. Physicochemical, Pharmaceutical and Biological Approaches Toward Designing Optimized and Efficient Hydrophobically Modified Chitosan-Based Polymeric Micelles As a Nanocarrier System for Targeted Delivery of Anticancer Drugs, Journal of Drug Targeting (2013)
33. Preparation and Characterization of a Sustained Release Buccoadhesive System for Delivery of Terbutaline Sulfate, Research in Pharmaceutical Sciences (2013)
34. Rapid, Sensitive, and Validated Hplc Method for Analysis of Metronidazole and Tinidazole Under Identical Chromatographic Conditions With Uv Detection and Liquid-Liquid Extraction: Application in Bioequivalence Studies, Acta Chromatographica (2013)
35. Simultaneous Spectrophotometric Determination of Amlodipine and Metoprolol by Principal Component Regression Multivariate Calibration and Comparison With Hplc, Journal of Reports in Pharmaceutical Sciences (2013)
36. Colon Specific Delivery of Budesonide Based on Triple Coated Pellets: In Vitro/In Vivo Evaluation, Acta Pharmaceutica (2012)
37. Formulation of Ldl Targeted Nanostructured Lipid Carriers Loaded With Paclitaxel: A Detailed Study of Preparation, Freeze Drying Condition, and in Vitro Cytotoxicity, Journal of Nanomaterials (2012)
38. Pectin Film Coated Pellets for Colon-Targeted Delivery of Budesonide: In-Vitro/In-Vivo Evaluation in Induced Ulcerative Colitis in Rat, Iranian Journal of Pharmaceutical Research (2012)
39. Development and Validation of a Rapid Hplc Method for Simultaneous Analysis of Budesonide and Its Novel Synthesized Hemiesters in Colon Specific Formulations, Research in Pharmaceutical Sciences (2011)
40. Development of a Prolonged-Release Gastroretentive Tablet Formulation of Ciprofloxacin Hydrochloride: Pharmacokinetic Characterization in Healthy Human Volunteers, International Journal of Pharmaceutics (2011)
41. Development of Novel Budesonide Pellets Based on Codes™ Technology: In Vitro/In Vivo Evaluation in Induced Colitis in Rats, DARU, Journal of Pharmaceutical Sciences (2011)
42. Microencapsulation of Budesonide With Dextran by Spray Drying Technique for Colon-Targeted Delivery: An in Vitro/In Vivo Evaluation in Induced Colitis in Rat, Journal of Microencapsulation (2011)
43. Preparation and in Vitro/In Vivo Evaluation of Dextran Matrix Tablets of Budesonide in Experimental Ulcerative Colitis in Rats, Drug Delivery (2011)
44. Preparation of Budesonide-Dextran Conjugates Using Glutarate Spacer As a Colon-Targeted Drug Delivery System: In Vitro/In Vivo Evaluation in Induced Ulcerative Colitis, Journal of Drug Targeting (2011)
45. Colon Delivery of Budesonide Using Solid Dispersion in Dextran for the Treatment and Secondary Prevention of Ulcerative Colitis in Rat, International Journal of Preventive Medicine (2010)
46. Comparative in Vitro and in Vivo Evaluation of Three Tablet Formulations of Amiodarone in Healthy Subjects, DARU, Journal of Pharmaceutical Sciences (2010)
47. Effect of Carrier Morphology and Surface Characteristics on the Development of Respirable Plga Microcapsules for Sustained-Release Pulmonary Delivery of Insulin, International Journal of Pharmaceutics (2010)
48. Effectiveness of Budesonide-Succinate-Dextran Conjugate As a Novel Prodrug of Budesonide Against Acetic Acid-Induced Colitis in Rats, International Journal of Colorectal Disease (2010)
49. Influence of Carrier Particle Size, Carrier Ratio and Addition of Fine Ternary Particles on the Dry Powder Inhalation Performance of Insulin-Loaded Plga Microcapsules, Powder Technology (2010)
50. Pharmacokinetics and Pharmacodynamics of Controlled Release Insulin Loaded Plga Microcapsules Using Dry Powder Inhaler in Diabetic Rats, Biopharmaceutics and Drug Disposition (2010)
51. The Effect of Process Parameters on the Size and Morphology of Poly(D, L-Lactide-Co-Glycolide) Micro/Nanoparticles Prepared by an Oil in Oil Emulsion/Solvent Evaporation Technique, Journal of Applied Polymer Science (2010)
52. A Novel Approach to Prepare Insulin-Loaded Poly (Lactic-Co-Glycolic Acid) Microcapsules and the Protein Stability Study, Journal of Pharmaceutical Sciences (2009)
53. Glycyrrhizin Production by in Vitro Cultured Glycyrrhiza Glabra Elicited by Methyl Jasmonate and Salicylic Acid1, Russian Journal of Plant Physiology (2009)
54. Particle Size Design of Plga Microspheres for Potential Pulmonary Drug Delivery Using Response Surface Methodology, Journal of Microencapsulation (2009)
55. The Effect of Formulation Variables on the Characteristics of Insulin-Loaded Poly(Lactic-Co-Glycolic Acid) Microspheres Prepared by a Single Phase Oil in Oil Solvent Evaporation Method, Colloids and Surfaces B: Biointerfaces (2009)
56. A Rapid and Sensitive Hplc Method for the Analysis of Celecoxib in Human Plasma: Application to Pharmacokinetic Studies, Daru (2008)
57. Development and Evaluation of Controlled-Release Buccoadhesive Verapamil Hydrochloride Tablets, Daru (2008)
58. Preparation and in Vitro Evaluation of Sustained-Release Matrix Tablets of Flutamide Using Synthetic and Naturally Occurring Polymers, Iranian Journal of Pharmaceutical Research (2008)
59. A Rapid and Sensitive Modified Hplc Method for Determination of Diclofenac in Human Plasma and Its Application in Pharmacokinetic Studies, Daru (2007)
60. A Rapid and Sensitive Hplc Method for the Analysis of Metronidazole in Human Plasma: Application to Single Dose Pharmacokinetic and Bioequivalence Studies, Daru (2006)
61. Development and Validation of a New Hplc Method for Determination of Lamotrigine and Related Compounds in Tablet Formulations, Journal of Pharmaceutical and Biomedical Analysis (2006)
62. In Vitro - in Vivo Correlation: From Theory to Applications, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques (2006)
63. In Vitro - in Vivo Relationships: Concepts, Regulatory Perspectives, Advances and Attempts, Journal of Pharmacy and Pharmaceutical Sciences (2006)
64. In Vitro-In Vivo Correlation: From Theory to Applications, Journal of Pharmacy and Pharmaceutical Sciences (2006)
65. Evaluation of Ecg Changes After Radiotherapy of Left Chest Wall by Electron in Patients With Left Breast Cancer Who Receive Anthracycline Based Chemotherapy Following Mastectomy, Journal of Research in Medical Sciences (2005)
66. Formulation of Sustained - Release Lithium Carbonate Matrix Tablets: Influence of Hydrophilic Materials on the Release Rate and in Vitro-In Vivo Evaluation, Journal of Pharmacy and Pharmaceutical Sciences (2004)
67. High Performance Liquid Chromatographic Determination, Pharmacokinetic and Comparative Bioavailability Studies of Cisapride, Journal of Pharmaceutical and Biomedical Analysis (2003)