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Phthalimides: Developments in Synthesis and Functionalization Publisher



Doraghi F1 ; Morshedsolouk MH1, 2 ; Zahedi NA3 ; Larijani B1 ; Mahdavi M1
Authors
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  3. 3. Department of Chemistry, Faculty of Education, Ghazni University, Ghazni, Afghanistan

Source: RSC Advances Published:2024


Abstract

Phthalimides, an important class of biologically active N-heterocycles, are not only found in pharmaceuticals, natural products, agrochemicals, polymers, and dyes, but also serve as building blocks in organic transformations. Many synthetic methods, including metal catalysis and metal-free systems, have been developed to prepare functionalized phthalimides. In this review, we describe the developments in the synthesis and functionalization of phthalimides over the past two decades. © 2024 The Royal Society of Chemistry.