Experimental and Computational Evidence for Kot-Bu-Promoted Synthesis of Oxopyrazino[1,2-A]Indoles

Experimental and Computational Evidence for Kot-Bu-Promoted Synthesis of Oxopyrazino[1,2-A]Indoles Publisher

Mahdavi M¹ ; Hassanzadehsoureshjan R² ; Saeedi M^{3, 4} ; Ariafard A^{5, 6} ; Babaahmadi R⁶ ; Ranjbar PR² ; Shafiee A¹

Show Affiliations

1. Department of Medicinal Chemistry, Faculty of Pharmacy, Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
2. School of Chemistry, University College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran
3. Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4. Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran
5. School of Physical Sciences (Chemistry), University of Tasmania, Private Bag 75, Hobart, 7001, TAS, Australia
6. Department of Chemistry, Faculty of Science, Central Tehran Branch, Islamic Azad University, Shahrak Gharb, Tehran, Iran

Source: RSC Advances Published:2015

Abstract

A novel series of oxopyrazino[1,2-a]indole derivatives were prepared via a two-step synthetic procedure including a Ugi-four-component reaction followed by the transition metal-free intramolecular hydroamination of Ugi adducts in the presence of KOt-Bu in DMF at room temperature. Density functional theory (DFT) calculations were also performed to elucidate the mechanistic aspects of the reaction. © The Royal Society of Chemistry.

Style	Citing Format
MLA	Mahdavi M, et al.. "Experimental and Computational Evidence for Kot-Bu-Promoted Synthesis of Oxopyrazino[1,2-A]Indoles." RSC Advances, vol. 5, no. 123, 2015, pp. 101353-101361.
APA	Mahdavi M, Hassanzadehsoureshjan R, Saeedi M, Ariafard A, Babaahmadi R, Ranjbar PR, Shafiee A (2015). Experimental and Computational Evidence for Kot-Bu-Promoted Synthesis of Oxopyrazino[1,2-A]Indoles. RSC Advances, 5(123), 101353-101361.
Chicago	Mahdavi M, Hassanzadehsoureshjan R, Saeedi M, Ariafard A, Babaahmadi R, Ranjbar PR, Shafiee A. "Experimental and Computational Evidence for Kot-Bu-Promoted Synthesis of Oxopyrazino[1,2-A]Indoles." RSC Advances 5, no. 123 (2015): 101353-101361.
Harvard	Mahdavi M et al. (2015) 'Experimental and Computational Evidence for Kot-Bu-Promoted Synthesis of Oxopyrazino[1,2-A]Indoles', RSC Advances, 5(123), pp. 101353-101361.
Vancouver	Mahdavi M, Hassanzadehsoureshjan R, Saeedi M, Ariafard A, Babaahmadi R, Ranjbar PR, et al.. Experimental and Computational Evidence for Kot-Bu-Promoted Synthesis of Oxopyrazino[1,2-A]Indoles. RSC Advances. 2015;5(123):101353-101361.
BibTex	@article{ author = {Mahdavi M and Hassanzadehsoureshjan R and Saeedi M and Ariafard A and Babaahmadi R and Ranjbar PR and Shafiee A}, title = {Experimental and Computational Evidence for Kot-Bu-Promoted Synthesis of Oxopyrazino[1,2-A]Indoles}, journal = {RSC Advances}, volume = {5}, number = {123}, pages = {101353-101361}, year = {2015} }
RIS	TY - JOUR AU - Mahdavi M AU - Hassanzadehsoureshjan R AU - Saeedi M AU - Ariafard A AU - Babaahmadi R AU - Ranjbar PR AU - Shafiee A TI - Experimental and Computational Evidence for Kot-Bu-Promoted Synthesis of Oxopyrazino[1,2-A]Indoles JO - RSC Advances VL - 5 IS - 123 SP - 101353 EP - 101361 PY - 2015 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract