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Prospective Epidemiological Research Studies in Iran (The Persian Cohort Study): Rationale, Objectives, and Design Publisher Pubmed



Poustchi H1 ; Eghtesad S1 ; Kamangar F2, 3 ; Etemadi A4 ; Keshtkar AA5 ; Hekmatdoost A6 ; Mohammadi Z1 ; Mahmoudi Z1 ; Shayanrad A1 ; Roozafzai F1 ; Sheikh M1 ; Jalaeikhoo A1 ; Somi MH7 ; Mansourghanaei F8 Show All Authors
Authors
  1. Poustchi H1
  2. Eghtesad S1
  3. Kamangar F2, 3
  4. Etemadi A4
  5. Keshtkar AA5
  6. Hekmatdoost A6
  7. Mohammadi Z1
  8. Mahmoudi Z1
  9. Shayanrad A1
  10. Roozafzai F1
  11. Sheikh M1
  12. Jalaeikhoo A1
  13. Somi MH7
  14. Mansourghanaei F8
  15. Najafi F9
  16. Bahramali E10
  17. Mehrparvar A11
  18. Ansarimoghaddam A12
  19. Enayati AA13
  20. Esmaeili Nadimi A14
  21. Rezaianzadeh A15
  22. Saki N16
  23. Alipour F17
  24. Kelishadi R18
  25. Rahimimovaghar A19
  26. Aminisani N20
  27. Boffetta P21
  28. Malekzadeh R3
Show Affiliations
Authors Affiliations
  1. 1. Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Iran
  2. 2. Department of Biology, School of Computer Mathematical and Natural Sciences, Morgan State University, Baltimore, MD, United States
  3. 3. Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran UMS, North Kargar Street, Tehran, 1411713135, Iran
  4. 4. Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States
  5. 5. Department of Health Sciences Education Development, School of Public Health, Tehran UMS, Tehran, Iran
  6. 6. Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Shahid Beheshti UMS, Tehran, Iran
  7. 7. Liver and Gastrointestinal Diseases Research Center, Tabriz UMS, Tabriz, Iran
  8. 8. Department of Gastroenterology, Gastrointestinal and Liver Diseases Research Center, Guilan UMS, Rasht, Iran
  9. 9. Research Center for Environmental Determinants of Health, School of Public Health, Kermanshah UMS, Kermanshah, Iran
  10. 10. Noncommunicable Diseases Research Center, Fasa UMS, Fasa, Iran
  11. 11. Department of Occupational Medicine, Faculty of Medicine, Shahid Sadoughi UMS, Yazd, Iran
  12. 12. Health Promotion Research Center, Zahedan UMS, Zahedan, Iran
  13. 13. School of Public Health and Health Sciences Research Center, Mazandaran UMS, Sari, Iran
  14. 14. Department of Cardiology, School of Medicine, Rafsanjan UMS, Rafsanjan, Iran
  15. 15. Department of Epidemiology, School of Health, Shiraz UMS, Shiraz, Iran
  16. 16. Department of Otolaryngology, Head and Neck Surgery, Hearing and Speech Research Center, Ahvaz Jundishapur UMS, Ahvaz, Iran
  17. 17. Eye Research Center, Farabi Eye Hospital, Tehran UMS, Tehran, Iran
  18. 18. Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Diseases, Isfahan UMS, Isfahan, Iran
  19. 19. Iranian National Center for Addiction Studies, Tehran UMS, Tehran, Iran
  20. 20. Department of Statistics and Epidemiology, Faculty of Health Sciences, Tabriz UMS, Tabriz, Iran
  21. 21. Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States

Source: American Journal of Epidemiology Published:2018


Abstract

Noncommunicable diseases (NCDs) account for 76% of deaths in Iran, and this number is on the rise, in parallel with global rates. Many risk factors associated with NCDs are preventable; however, it is first necessary to conduct observational studies to identify relevant risk factors and the most appropriate approach to controlling them. Iran is a multiethnic country; therefore, in 2014 the Ministry of Health and Medical Education launched a nationwide cohort study - Prospective Epidemiological Research Studies in Iran (PERSIAN) - in order to identify the most prevalent NCDs among Iran's ethnic groups and to investigate effective methods of prevention. The PERSIAN study consists of 4 population-based cohorts; the adult component (the PERSIAN Cohort Study), described in this article, is a prospective cohort study including 180,000 persons aged 35-70 years from 18 distinct areas of Iran. Upon joining the cohort, participants respond to interviewer-administered questionnaires. Blood, urine, hair, and nail samples are collected and stored. To ensure consistency, centrally purchased equipment is sent to all sites, and the same team trains all personnel. Routine visits and quality assurance/control measures are taken to ensure protocol adherence. Participants are followed for 15 years postenrollment. The PERSIAN study is currently in the enrollment phase; cohort profiles will soon emerge. © The Author(s) 2018. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved.
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