Photocatalytic Reduction of Imatinib Mesylate and Imipenem on Electrochemical Synthesized Al2w3o12 Nanoparticle: Optimization, Investigation of Electrocatalytic and Antimicrobial Activity Publisher



Mirsadeghi S¹ ; Zandavar H² ; Rahimi M² ; Tooski HF² ; Rajabi HR³ ; Rahiminasrabadi M^{4, 5} ; Sohouli E⁶ ; Larijani B¹ ; Pourmortazavi SM² Show Affiliations
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects Published:2020

Abstract

Herein, we describe an electrochemical, economically viable, rapid, and optimized procedure to synthesize of sphere Al2W3O12 nanoparticles of 40 nm mean particle size. By using various techniques, size, morphology, chemical structure, and crystallinity were depicted. Considerably, the Al2W3O12 nanoparticles under UV light showed admirable elimination effectiveness for the reduction of three impurities included methyl orange as dye, imatinib mesylate as an anticancer drug with endocrine and mutagenic disruptive effects and imipenem as an antibiotic drug, and the probable mechanism is also suggested. Nearly 90% of methyl orange, 56% of imatinib mesylate, and 75% of imipenem are eradicated in 5000 s, the 1500s, and 1200s on the synthesized nanoparticles. Additionally, the nanoparticles displayed antimicrobial action versus Bacillus, Escherichia coli, and Staphylococcus aureus in the presence of 6.25, 12.5, and 25 mg/ml concentration of nanoparticles. On the other hand, the carbon paste electrode modified with Al2W3O12 nanoparticles was prepared, and its electrocatalytic activity was investigated in an acidic medium for hydrogen evolution reaction by linear sweep voltammetry method. The modified carbon paste electrode has a higher current density and lowers negative potential in the hydrogen evolution reaction compared to the unmodified electrode; the results of linear sweep voltammetry showed. Hence, this article has revealed an innovatory way for preparation Al2W3O12 nanoparticles and represented their multifunctional ability as the photocatalyst, antimicrobial agent and electrocatalytic activity. © 2019 Elsevier B.V.