Tehran University of Medical Sciences

Science Communicator Platform

Share By
Nanomaterials As a Therapeutic Platform for Covid-19 Publisher



Nasab MHF ; Manavi MA ; Hamrahi M ; Khonsari F ; Gelivarisarshari M ; Foroohari A ; Dehghani M ; Ranjbar S ; Atyabi F
Authors

Source: Precision Nanomedicine Published:2026


Abstract

COVID-19 remains a major global health challenge, highlighting the urgent need for more effective treatments. Nanotechnology-based drug delivery systems provide a promising platform for overcoming the limitations of traditional antiviral, anti-inflammatory, and immunomodulatory therapies. Carefully designed nanocarriers can improve how drugs move through the body, reach target cells, and are taken up, increasing antiviral effectiveness and potentially lowering systemic toxicity. In addition to serving as carriers for approved antiviral drugs, many nanomaterials possess their own antiviral properties. Since dysregulated inflammation and cytokine storms are key factors in severe COVID-19, nanomedicine also offers ways to deliver anti-inflammatory and immunomodulatory agents directly to sites of immune activation, enabling more precise control of interleukin and cytokine release. This review covers recent developments in the design and use of nanocarriers and nanomaterials for the prevention, diagnosis, and treatment of COVID-19, and discusses future prospects for nanotechnology in the management of viral infections. ©The Author(s) 2024.
Related Docs
View other Related Docs
1. Nanomaterials in the Covid-19 Era: A Promising Therapeutic Platform, Precision Nanomedicine (2025)
2. Nanomedicine “New Food for an Old Mouth”: Novel Approaches for the Treatment of Covid-19, Drug Delivery Letters (2023)
3. Nanotheranostics Against Covid-19: From Multivalent to Immune-Targeted Materials, Journal of Controlled Release (2020)
Experts (# of related papers)
View all Related Experts
Farid Dorkoosh (3)
Fatemeh Atyabi (3)
Other Related Docs
4. Aptamer-Decorated Nanocarriers for Viral Adsorption: A Special Look at Covid-19, Molecular Therapy Nucleic Acids (2024)
5. Nanobodies As Powerful Pulmonary Targeted Biotherapeutics Against Sars-Cov-2, Pharmaceutical Point of View, Biochimica et Biophysica Acta - General Subjects (2021)
6. Innovative Nanotechnology for Infectious and Inflammatory Disease Control: From Diagnostics to Therapeutics, Biomedicine and Pharmacotherapy (2025)
7. State-Of-The-Art Cerium Nanoparticles As Promising Agents Against Human Viral Infections, Biomedicine and Pharmacotherapy (2022)
8. Nano Antiviral Photodynamic Therapy: A Probable Biophysicochemical Management Modality in Sars-Cov-2, Expert Opinion on Drug Delivery (2021)
9. State-Of-The-Art of Nanodiagnostics and Nanotherapeutics Against Sars-Cov-2, ACS Applied Materials and Interfaces (2021)
10. Therapeutic Potentials and Candidates for Covid-19, Iranian Journal of Science (2023)
11. Therapeutic and Diagnostic Applications of Nanoparticles in the Management of Covid-19: A Comprehensive Overview, Virology Journal (2022)
12. The Quest for a Better Fight: How Can Nanomaterials Address the Current Therapeutic and Diagnostic Obstacles in the Fight Against Covid-19?, Journal of Drug Delivery Science and Technology (2022)
13. Viral Nanoparticles-Mediated Delivery of Therapeutic Cargo, Advanced Therapeutics (2023)
14. The Significance of Bioengineered Nanoplatforms Against Sars-Cov-2: From Detection to Genome Editing, Life Sciences (2021)
15. Nanostructures for Prevention, Diagnosis, and Treatment of Viral Respiratory Infections: From Influenza Virus to Sars-Cov-2 Variants, Journal of Nanobiotechnology (2023)
16. Covid-19 Immunotherapy: Treatment Based on the Immune Cell-Mediated Approaches, International Immunopharmacology (2022)
17. Application of Nano-Based Systems for Drug Delivery and Targeting: A Review, Journal of Nanoparticle Research (2020)
18. Therapeutic Strategies for Covid-19 Patients: An Update, Infectious Disorders - Drug Targets (2022)
19. Development of a T Cell-Targeted Sirna Delivery System Against Hiv-1 Using Modified Superparamagnetic Iron Oxide Nanoparticles: An in Vitro Study, Journal of Pharmaceutical Sciences (2022)
20. Covid-19: Transmission, Prevention, and Potential Therapeutic Opportunities, Clinica Chimica Acta (2020)