Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica)

Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica) Publisher

Gavanji K¹ ; Babaei Afrapoli Z¹ ; Rahimnia R¹ ; Negahdari B² ; Faridimajidi R¹

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1. Department of Medical Nanotechnology, School of Advanced Technologies in Medcine, Tehran University of Medical Sciences (TUMS), Tehran, Iran
2. Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran

Source: Analytical Letters Published:2024

Abstract

This study evaluated the application of carboxylated multi-walled carbon nanotubes (MWCNTs) as a label in immunochromatographic assay for morphine detection. MWCNTs were carboxylated using nitric acid and characterized by Fourier-transform infrared (FTIR) spectroscopy, Raman spectroscopy, field emission scanning microscopy (FESEM), and dynamic light scattering (DLS). The optimum concentration of polyvinyl pyrrolidone (PVP) as a surfactant for homogenous dispersion of MWCNTs was determined by ultraviolet-visible spectroscopy to be 0.5 mg/mL. The zeta potential of MWCNTs before adding PVP was −41.9 ± 1.02 mV, and after adding PVP, −54.1 ± 0.25 mV. On the surface of MWCNTs, the anti-morphine antibody (AM antibody) had a binding effectiveness ranging from 91.1% to 95.5%. The AM antibody-MWCNTs were conjugated to create immunochromatographic test strips. The visual limit of detection (vLOD) was 1.0 ng/mL and the cutoff concentration (COC) was 10.0 ng/mL. Compared to previous study, carboxylated-MWCNTs as a one-dimensional nanomaterial improved the sensitivity of immunochromatographic assay strips and may be utilized to develop the sensitive immunochromatographic assays. © 2024 Taylor & Francis Group, LLC.

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Style	Citing Format
MLA	Gavanji K, et al.. "Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica)." Analytical Letters, vol. , no. , 2024, pp. -.
APA	Gavanji K, Babaei Afrapoli Z, Rahimnia R, Negahdari B, Faridimajidi R (2024). Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica). Analytical Letters, (), -.
Chicago	Gavanji K, Babaei Afrapoli Z, Rahimnia R, Negahdari B, Faridimajidi R. "Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica)." Analytical Letters , no. (2024): -.
Harvard	Gavanji K et al. (2024) 'Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica)', Analytical Letters, (), pp. -.
Vancouver	Gavanji K, Babaei Afrapoli Z, Rahimnia R, Negahdari B, Faridimajidi R. Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica). Analytical Letters. 2024;():-.
BibTex	@article{ author = {Gavanji K and Babaei Afrapoli Z and Rahimnia R and Negahdari B and Faridimajidi R}, title = {Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica)}, journal = {Analytical Letters}, volume = {}, number = {}, pages = {-}, year = {2024} }
RIS	TY - JOUR AU - Gavanji K AU - Babaei Afrapoli Z AU - Rahimnia R AU - Negahdari B AU - Faridimajidi R TI - Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica) JO - Analytical Letters VL - IS - SP - EP - PY - 2024 ER -

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