Association Between Uncoupling Protein 2, Adiponectin and Resting Energy Expenditure in Obese Women With Normal and Low Resting Energy Expenditure

Association Between Uncoupling Protein 2, Adiponectin and Resting Energy Expenditure in Obese Women With Normal and Low Resting Energy Expenditure Publisher Pubmed

Taghadomi Masoumi Z¹ ; Eshraghian MR² ; Hedayati M³ ; Pishva H¹

Show Affiliations

1. Department of cellular-Molecular Nutrition, School of Nutrition Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
3. Cellular-Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University, Tehran, Iran

Source: Gynecological Endocrinology Published:2018

Abstract

Obesity is recognized as the most prevalent metabolic disease worldwide. Decreases in energy expenditure may increase risk of obesity. One of the key regulators of energy balance is uncoupling protein2 (UCP2), a transporter protein presents in mitochondrial inner membrane. Moreover, adiponectin is the most abundant adipocytokine, it may play a role in energy metabolism and gene expression of UCP2. The aim of this study was to investigate potential associations between the level of uncoupling protein 2 and adiponectin and their relationship with REE (Resting Energy Expenditure) in obese women with normal and low resting energy expenditure. A total of 49 subjects (women, 25–50 years old), were included in current study, 16 subjects with BMI > 30 and low resting energy expenditure, 17 subjects with BMI > 30 and normal resting energy expenditure and 16 non-obese subjects as a control group. Anthropometric, body composition parameters and resting energy expenditure were measured. Plasma adiponectin, UCP2 protein and total protein in PBMC were determined. Measured resting energy expenditure in obese subjects with low REE was significantly lower than other groups. Plasma adiponectin in the obese subjects with low REE was significantly lower compared to normal weight group. There was a significant relationship between ‘UCP2 protein/Total protein’ ratio and plasma adiponectin in obese group with low REE and in three groups when we pooled. There was a significant association between REE and plasma adiponectin in three groups when we pooled. There was a significant association between plasma adiponectin and REE. Moreover, there was a significant relationship between UCP2 and REE. © 2017 Informa UK Limited, trading as Taylor & Francis Group.

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Style	Citing Format
MLA	Taghadomi Masoumi Z, et al.. "Association Between Uncoupling Protein 2, Adiponectin and Resting Energy Expenditure in Obese Women With Normal and Low Resting Energy Expenditure." Gynecological Endocrinology, vol. 34, no. 2, 2018, pp. 166-170.
APA	Taghadomi Masoumi Z, Eshraghian MR, Hedayati M, Pishva H (2018). Association Between Uncoupling Protein 2, Adiponectin and Resting Energy Expenditure in Obese Women With Normal and Low Resting Energy Expenditure. Gynecological Endocrinology, 34(2), 166-170.
Chicago	Taghadomi Masoumi Z, Eshraghian MR, Hedayati M, Pishva H. "Association Between Uncoupling Protein 2, Adiponectin and Resting Energy Expenditure in Obese Women With Normal and Low Resting Energy Expenditure." Gynecological Endocrinology 34, no. 2 (2018): 166-170.
Harvard	Taghadomi Masoumi Z et al. (2018) 'Association Between Uncoupling Protein 2, Adiponectin and Resting Energy Expenditure in Obese Women With Normal and Low Resting Energy Expenditure', Gynecological Endocrinology, 34(2), pp. 166-170.
Vancouver	Taghadomi Masoumi Z, Eshraghian MR, Hedayati M, Pishva H. Association Between Uncoupling Protein 2, Adiponectin and Resting Energy Expenditure in Obese Women With Normal and Low Resting Energy Expenditure. Gynecological Endocrinology. 2018;34(2):166-170.
BibTex	@article{ author = {Taghadomi Masoumi Z and Eshraghian MR and Hedayati M and Pishva H}, title = {Association Between Uncoupling Protein 2, Adiponectin and Resting Energy Expenditure in Obese Women With Normal and Low Resting Energy Expenditure}, journal = {Gynecological Endocrinology}, volume = {34}, number = {2}, pages = {166-170}, year = {2018} }
RIS	TY - JOUR AU - Taghadomi Masoumi Z AU - Eshraghian MR AU - Hedayati M AU - Pishva H TI - Association Between Uncoupling Protein 2, Adiponectin and Resting Energy Expenditure in Obese Women With Normal and Low Resting Energy Expenditure JO - Gynecological Endocrinology VL - 34 IS - 2 SP - 166 EP - 170 PY - 2018 ER -

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