Rapid Microwave-Assisted Synthesis of Pvp-Coated Ultrasmall Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging

Rapid Microwave-Assisted Synthesis of Pvp-Coated Ultrasmall Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging Publisher

Vahdatkhah P¹ ; Madaah Hosseini HR¹ ; Khodaei A¹ ; Montazerabadi AR³ ; Irajirad R² ; Oghabian MA^{2, 3} ; Delavari H H⁴

Source: Chemical Physics Published:2015

Abstract

Synthesis of polyvinyl pyrrolidone (PVP) coated ultrasmall Gd2O3 nanoparticles (NPs) with enhanced T1-weighted signal intensity and r2/r1 ratio close to unity is performed by a microwave-assisted polyol process. PVP coated Gd2O3NPs with spherical shape and uniform size of 2.5 ± 0.5 nm have been synthesized below 5 min and structure and morphology confirmed by HRTEM, XRD and FTIR. The longitudinal (r1) and transversal relaxation (r2) of Gd2O3NPs is measured by a 3 T MRI scanner. The results showed considerable increasing of relaxivity for Gd2O3NPs in comparison to gadolinium chelates which are commonly used for clinical magnetic resonance imaging. In addition, a mechanism for Gd2O3NPs formation and in situ surface modification of PVP-grafted Gd2O3NPs is proposed. © 2015 Elsevier B.V. All rights reserved.

Style	Citing Format
MLA	Vahdatkhah P, et al.. "Rapid Microwave-Assisted Synthesis of Pvp-Coated Ultrasmall Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging." Chemical Physics, vol. 453-454, no. , 2015, pp. 35-41.
APA	Vahdatkhah P, Madaah Hosseini HR, Khodaei A, Montazerabadi AR, Irajirad R, Oghabian MA, Delavari H H (2015). Rapid Microwave-Assisted Synthesis of Pvp-Coated Ultrasmall Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging. Chemical Physics, 453-454(), 35-41.
Chicago	Vahdatkhah P, Madaah Hosseini HR, Khodaei A, Montazerabadi AR, Irajirad R, Oghabian MA, Delavari H H. "Rapid Microwave-Assisted Synthesis of Pvp-Coated Ultrasmall Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging." Chemical Physics 453-454, no. (2015): 35-41.
Harvard	Vahdatkhah P et al. (2015) 'Rapid Microwave-Assisted Synthesis of Pvp-Coated Ultrasmall Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging', Chemical Physics, 453-454(), pp. 35-41.
Vancouver	Vahdatkhah P, Madaah Hosseini HR, Khodaei A, Montazerabadi AR, Irajirad R, Oghabian MA, et al.. Rapid Microwave-Assisted Synthesis of Pvp-Coated Ultrasmall Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging. Chemical Physics. 2015;453-454():35-41.
BibTex	@article{ author = {Vahdatkhah P and Madaah Hosseini HR and Khodaei A and Montazerabadi AR and Irajirad R and Oghabian MA and Delavari H H}, title = {Rapid Microwave-Assisted Synthesis of Pvp-Coated Ultrasmall Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging}, journal = {Chemical Physics}, volume = {453-454}, number = {}, pages = {35-41}, year = {2015} }
RIS	TY - JOUR AU - Vahdatkhah P AU - Madaah Hosseini HR AU - Khodaei A AU - Montazerabadi AR AU - Irajirad R AU - Oghabian MA AU - Delavari H H TI - Rapid Microwave-Assisted Synthesis of Pvp-Coated Ultrasmall Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging JO - Chemical Physics VL - 453-454 IS - SP - 35 EP - 41 PY - 2015 ER -

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