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Melatonin Could Be Beneficial in Sars-Cov-2 Therapy Publisher



Rahimi SB1 ; Adli AH2, 3
Authors
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Authors Affiliations
  1. 1. Department of Microbiology, Golestan University of Medical Sciences, Gorgan, Iran
  2. 2. Department of Microbiology, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Department of Virology, Tehran University of Medical Sciences, Tehran, Iran

Source: Natural Products Journal Published:2021


Abstract

Novel coronavirus (SARS-CoV-2) can infect the respiratory tract and cause severe respiratory syndrome. The excessive inflammatory response is involved in the pathogenicity of the SARS-CoV-2. Symptoms of SARS-CoV-2 are generally associated with immunopathogenesis and may result in pulmonary tissue damage. Melatonin is a natural and multifunctional hormone that is involved in both physiological and pathological conditions in the body, such as immune modula-tion, anti-inflammation, and antioxidant. Melatonin is found in foods, animal and human milk and increases the expression of anti-inflammatory cytokines and, as an adjuvant treatment in SARS--CoV-2 infection, it may have considerable therapeutic potential, because of its safety and immuno-modulatory effects. © 2021 Bentham Science Publishers.
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