Global Trend of Ovarian Cancer Among Old Age Women: An Analysis by Socio-Demographic Index and Geographic Regions Publisher



Allahqoli L¹ ; Mazidimoradi A² ; Rezaei F³ ; Pasokh Z² ; Hakimi S⁴ ; Momenimovahed Z⁵ ; Aghamohammadi SZ⁶ ; Rahmani A⁷ ; Fallahi A⁸ ; Karimzadeh A⁹ ; Salehiniya H¹⁰ ; Alkatout I¹¹ Show Affiliations
Source: Indian Journal of Gynecologic Oncology Published:2024

Abstract

Background: Ovarian cancer is a major cause of cancer-related deaths among women. This study aims to describe the trend of ovarian cancer in women over 55 years old from 2010- 2019 by socio-demographic index (SDI) and geographical regions. Methods: We collected data on ovarian cancer annually between 2010 and 2019 from the 2019 Global Burden of Disease (GBD) study to analyze the morbidity, mortality rates, and disability-adjusted life years (DALYs) associated with ovarian cancer across different parameters such as global trend, age groups, SDI, continents, World Bank Regions, World Health Organization regions, GBD regions, and National and territorial division. This analysis spans from 2010 to 2019 and encompasses data from 204 countries and territories. A confidence level of 95% was selected. Results: Between 2010 and 2019, the global incidence of ovarian cancer increased from 135,617 to 179,816 cases, marking a 1.3-fold rise, alongside a 19% increase in incidence rate. Global OC mortality also surged from 114,477 to 151,198 cases during the same period, with a 1.3-fold increase and a 15% rise in death rate. Ovarian cancer prevalence showed a similar trend, increasing from 414,042 to 552,576 cases, with a 3% rise in prevalence rate, while the number of ovarian cancer DALYs increased from 2,426,509 to 3,216,000 cases, reflecting a 1% rise in DALYs rate. Incidence, death, prevalence, and DALYs numbers of ovarian cancer increased across all age groups, with the highest increase observed in the 65–69 years age group. High SDI countries had the highest incidence, death, prevalence, and DALYs numbers, while low SDI countries showed increasing trends. Asia exhibited the highest incidence, death, prevalence, and DALYs numbers of ovarian cancer, with increasing trends observed in prevalence rates. High-income countries had the highest incidence, death, prevalence, and DALYs numbers, with slight decreases in rates. Europe and Western Europe showed the highest incidence, death, prevalence, and DALYs numbers, with declining trends in rates. Conclusion: Overall, the findings underscore the growing burden of ovarian cancer among older women globally, driven by factors such as demographic aging, shifts in lifestyle patterns, and advancements in diagnostic methodologies. Addressing these challenges requires tailored interventions informed by regional contexts and national-level insights to promote equitable access to quality healthcare services worldwide. © The Author(s) under exclusive licence to Association of Gynecologic Oncologists of India 2024.