The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Publisher Pubmed

Ding F¹ ; Ma B² ; Nazaryvannani A³ ; Kordvarkaneh H⁴ ; Fatahi S⁵ ; Papageorgiou M⁶ ; Rahmani J⁴ ; Poursoleiman F⁴ ; Junior Borges Do Nascimento I⁷ ; Li H² ; Han D² ; Wang D²

Show Affiliations

1. Emergency Department, Harbin fifth hospital, Harbin, 150040, Heilongjiang, China
2. Cardiovascular Medicine Department, Harbin Fifth Hospital, Harbin, 150040, Heilongjiang, China
3. Department of Cellular and Molecular Nutrition, Studentsâ€™ Scientific Research Center (SSRC) School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Iran
4. Department of Clinical Nutrition and Dietetics, Student Research Committee, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5. Student Research Committee, Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
6. Division of Bone Diseases, Department of Internal Medicine Specialties, Geneva University Hospitals & Faculty of Medicine, Geneva 14, Switzerland
7. University Hospital and School of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

Source: Nutrition# Metabolism and Cardiovascular Diseases Published:2020

Abstract

Background and aim: This systematic review and meta-analysis aimed to assess the effects of green coffee bean extract (GCBE) supplementation on lipid profile in adults. Methods and results: The PubMed/Medline, Scopus, Web of sciences, and Google Scholar were systematically searched for randomized controlled trials available in English and published before February 2019. The meta-analysis was conducted using fixed effects models, and between-study heterogeneity was assessed by Cochran's Q test and I2. A total of 17 effect sizes were included in the meta-analysis. Combined effect sizes on serum total cholesterol concentrations revealed significant effects of GCBE supplementation on serum total cholesterol [weighted mean difference (WMD): −4.51 mg/dL, 95% confidence interval (CI): −6.89, −2.12, p < 0.001], low density lipoprotein-cholesterol (LDL-C) (WMD: −4.38 mg/dL, 95% CI: −6.44, −2.31, p < 0.001), and high density lipoprotein-cholesterol (HDL-C) (WMD: 2.63 mg/dL, 95% CI: 2.20, 3.07, p < 0.001) compared to controls. Nevertheless, no significant changes were observed in serum triglycerides levels (WMD: −4.34 mg/dL, 95% CI: −9.00, 0.32, p = 0.068). Conclusion: The evidence from available studies suggests that the GCBE supplementation leads to significant reductions in total cholesterol, HDL-C, and LDL-C levels, and has modest, but, non-significant effects on triglycerides levels. © 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University

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Style	Citing Format
MLA	Ding F, et al.. "The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials." Nutrition# Metabolism and Cardiovascular Diseases, vol. 30, no. 1, 2020, pp. 1-10.
APA	Ding F, Ma B, Nazaryvannani A, Kordvarkaneh H, Fatahi S, Papageorgiou M, Rahmani J, Poursoleiman F, Junior Borges Do Nascimento I, Li H, Han D, Wang D (2020). The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrition# Metabolism and Cardiovascular Diseases, 30(1), 1-10.
Chicago	Ding F, Ma B, Nazaryvannani A, Kordvarkaneh H, Fatahi S, Papageorgiou M, Rahmani J, et al.. "The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials." Nutrition# Metabolism and Cardiovascular Diseases 30, no. 1 (2020): 1-10.
Harvard	Ding F et al. (2020) 'The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials', Nutrition# Metabolism and Cardiovascular Diseases, 30(1), pp. 1-10.
Vancouver	Ding F, Ma B, Nazaryvannani A, Kordvarkaneh H, Fatahi S, Papageorgiou M, et al.. The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrition# Metabolism and Cardiovascular Diseases. 2020;30(1):1-10.
BibTex	@article{ author = {Ding F and Ma B and Nazaryvannani A and Kordvarkaneh H and Fatahi S and Papageorgiou M and Rahmani J and Poursoleiman F and Junior Borges Do Nascimento I and Li H and Han D and Wang D}, title = {The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials}, journal = {Nutrition# Metabolism and Cardiovascular Diseases}, volume = {30}, number = {1}, pages = {1-10}, year = {2020} }
RIS	TY - JOUR AU - Ding F AU - Ma B AU - Nazaryvannani A AU - Kordvarkaneh H AU - Fatahi S AU - Papageorgiou M AU - Rahmani J AU - Poursoleiman F AU - Junior Borges Do Nascimento I AU - Li H AU - Han D AU - Wang D TI - The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials JO - Nutrition# Metabolism and Cardiovascular Diseases VL - 30 IS - 1 SP - 1 EP - 10 PY - 2020 ER -

Style

Citing Format

MLA

Ding F, et al.. "The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials." Nutrition# Metabolism and Cardiovascular Diseases, vol. 30, no. 1, 2020, pp. 1-10.

APA

Ding F, Ma B, Nazaryvannani A, Kordvarkaneh H, Fatahi S, Papageorgiou M, Rahmani J, Poursoleiman F, Junior Borges Do Nascimento I, Li H, Han D, Wang D (2020). The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrition# Metabolism and Cardiovascular Diseases, 30(1), 1-10.

Chicago

Ding F, Ma B, Nazaryvannani A, Kordvarkaneh H, Fatahi S, Papageorgiou M, Rahmani J, et al.. "The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials." Nutrition# Metabolism and Cardiovascular Diseases 30, no. 1 (2020): 1-10.

Harvard

Ding F et al. (2020) 'The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials', Nutrition# Metabolism and Cardiovascular Diseases, 30(1), pp. 1-10.

Vancouver

Ding F, Ma B, Nazaryvannani A, Kordvarkaneh H, Fatahi S, Papageorgiou M, et al.. The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrition# Metabolism and Cardiovascular Diseases. 2020;30(1):1-10.

BibTex

@article{ author = {Ding F and Ma B and Nazaryvannani A and Kordvarkaneh H and Fatahi S and Papageorgiou M and Rahmani J and Poursoleiman F and Junior Borges Do Nascimento I and Li H and Han D and Wang D}, title = {The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials}, journal = {Nutrition# Metabolism and Cardiovascular Diseases}, volume = {30}, number = {1}, pages = {1-10}, year = {2020} }

RIS

TY - JOUR
AU - Ding F
AU - Ma B
AU - Nazaryvannani A
AU - Kordvarkaneh H
AU - Fatahi S
AU - Papageorgiou M
AU - Rahmani J
AU - Poursoleiman F
AU - Junior Borges Do Nascimento I
AU - Li H
AU - Han D
AU - Wang D
TI - The Effects of Green Coffee Bean Extract Supplementation on Lipid Profile in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
JO - Nutrition# Metabolism and Cardiovascular Diseases
VL - 30
IS - 1
SP - 1
EP - 10
PY - 2020
ER -

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Abstract