Tehran University of Medical Sciences

Science Communicator Platform

Share By
Autophagy in the Regulation of Radio-Resistance Publisher



M Hashemi MEHRDAD ; P Rahimzadeh PAYMAN ; Am Jafari Ali MOGHADAS ; L Mohammadnahal LEILA ; N Zali NEDA ; S Saghari SAM ; S Hajimazdarany SHIMA ; M Farid MAHDIEH ; A Bidardel ATOUSA ; K Shahpasand KOUROSH
Authors

Source: Published:2025


Abstract

Autophagy, recognized as a mechanism of cell death, plays a pivotal role in the regulation of various biological processes. It exhibits dual roles, acting both protectively and lethally within cells. This process has garnered attention for its potential in addressing numerous pathological conditions, particularly cancer. Radiotherapy is a key treatment modality for cancer, yet tumor cells can develop resistance to this form of therapy. This chapter delves into the role of autophagy in influencing radioresistance in cancer treatment. © 2025 Elsevier B.V., All rights reserved.
Other Related Docs
5. The Question of Survival or Death: What Is the Role of Autophagy in Acute Myeloid Leukemia (Aml)?, International Journal of Hematology-Oncology and Stem Cell Research (2022)
6. Metastatic Outgrowth Via the Two-Way Interplay of Autophagy and Metabolism, Biochimica et Biophysica Acta - Molecular Basis of Disease (2024)
13. Regulation of Cell Death Mechanisms by Melatonin: Implications in Cancer Therapy, Anti-Cancer Agents in Medicinal Chemistry (2022)
17. Targeted Cancer Therapy: Review Article, Tehran University Medical Journal (2018)