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Stimuli-Responsive Injectable Chitosan-Based Hydrogels for Controlled Drug Delivery Systems Publisher



Garshasbi H1 ; Salehi S1 ; Naghib SM1 ; Ghorbanzadeh S2 ; Zhang W2
Authors

Source: Frontiers in Bioengineering and Biotechnology Published:2023


Abstract

In the last decade, injectable hydrogels have attracted a lot of attention due to their excellent functional properties in the field of drug delivery for precise, non-invasive and focused tissue locations. Therefore, designing drug delivery systems (DDS) responsive to hydrogel stimuli to release a drug to an external stimulus with various advantages, can be very challenging. Due to their biocompatibility, mucosal adhesion, and hemostatic activity, chitosan (Chitosan)-based hydrogels offer a lot of potential for tissue engineering and drug delivery. It can be difficult to manage the structure of these stimuli-responsive CS hydrogels or they may require additional crosslinking agents, such as hydrogels with dual pH and thermo-responsiveness. Therefore, it is crucial to create these hydrogels for medicinal applications. Copyright © 2023 Garshasbi, Salehi, Naghib, Ghorbanzadeh and Zhang.
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