Tehran University of Medical Sciences

Science Communicator Platform

Share By
Comparison of Immune Response Between Sars, Mers, and Covid-19 Infection, Perspective on Vaccine Design and Development Publisher Pubmed



Ansariniya H1 ; Seifati SM2 ; Zaker E3 ; Zare F2, 4
Authors

Source: BioMed Research International Published:2021


Abstract

Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and Coronavirus Disease 2019 (COVID-19) infections are the three epidemiological diseases caused by the Coronaviridae family. Perceiving the immune responses in these infections and the escape of viruses could help us design drugs and vaccines for confronting these infections. This review investigates the innate and adaptive immune responses reported in the infections of the three coronaviruses SARS, MERS, and COVID-19. Moreover, the present study can trigger researchers to design and develop new vaccines and drugs based on immune system responses. In conclusion, due to the need for an effective and efficient immune stimulation against coronavirus, a combination of several strategies seems necessary for developing the vaccine. © 2021 Hossein Ansariniya et al.
Related Docs
View other Related Docs
1. Current Advances and Challenges in Covid-19 Vaccine Development: From Conventional Vaccines to Next-Generation Vaccine Platforms, Molecular Biology Reports (2022)
2. Recent Advances in Passive Immunotherapies for Covid-19: The Evidence-Based Approaches and Clinical Trials, International Immunopharmacology (2022)
3. Influenza Vaccine: Where Are We and Where Do We Go?, Reviews in Medical Virology (2019)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (5)
Farhad Rezaei (2)
Other Related Docs
4. Role of Toll-Like Receptors in the Pathogenesis of Covid-19, Journal of Medical Virology (2021)
5. A Comparison Between Sars-Cov-1 and Sars-Cov2: An Update on Current Covid-19 Vaccines, DARU# Journal of Pharmaceutical Sciences (2022)
6. An Outlook on Antigen-Specific Adoptive Immunotherapy for Viral Infections With a Focus on Covid-19, Cellular Immunology (2021)
7. A Review of Virus-Like Particle-Based Sars-Cov-2 Vaccines in Clinical Trial Phases, Iranian Journal of Pharmaceutical Research (2022)
8. Monoclonal Antibody As a Potential Anti-Covid-19, Biomedicine and Pharmacotherapy (2020)
9. Hypothesis: Designation of Liposomal Scavenger System for Fight Against 2019-Ncov, Infectious Disorders - Drug Targets (2022)
10. Induction of Protective Immune Response to Intranasal Administration of Influenza Virus-Like Particles in a Mouse Model, Journal of Cellular Physiology (2019)
11. Covid-19 Vaccines Mix-And-Match: The Concept, the Efficacy and the Doubts, Journal of Medical Virology (2022)
12. The Prophylaxis and Treatment Potential of Supplements for Covid-19, European Journal of Pharmacology (2020)
13. Phytopharmaceuticals Mediated Furin and Tmprss2 Receptor Blocking: Can It Be a Potential Therapeutic Option for Covid-19?, Phytomedicine (2021)
14. Virtual Screening Based on the Structure of More Than 105 Compounds Against Four Key Proteins of Sars-Cov-2: Mpro, Srbd, Rdrp, and Plpro, Informatics in Medicine Unlocked (2022)
15. A Comprehensive Review of Mrna-Based Vaccines for Covid-19, a New Era in Pharmaceuticals: Unspecified and Unknown Aspects, Effects and Challenges, Current Topics in Medicinal Chemistry (2025)
16. An Overview on the Treatments and Prevention Against Covid-19, Virology Journal (2023)
17. Potential Therapeutic Options for Covid-19: An Update on Current Evidence, European Journal of Medical Research (2022)
18. Review on Approved and Inprogress Covid-19 Vaccines, Iranian Journal of Pharmaceutical Research (2022)
19. Potential Therapeutic Applications of Extracellular Vesicles in the Immunopathogenesis of Covid-19, Pathology Research and Practice (2023)
20. Potential Role of Interferons in Treating Covid-19 Patients, International Immunopharmacology (2021)