Dysregulated Expression of Mirnas in Immune Thrombocytopenia

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Dysregulated Expression of Mirnas in Immune Thrombocytopenia Publisher Pubmed

Jafarzadeh A^{1, 2} ; Marzban H³ ; Nemati M^{4, 5} ; Jafarzadeh S⁶ ; Mahjoubintehran M⁷ ; Hamblin MR⁸ ; Mirzaei H^{9, 10} ; Mirzaei HR¹¹

Source: Epigenomics Published:2021

Abstract

In recent years the critical role of miRNAs has been established in many diseases, including autoimmune disorders. Immune thrombocytopenia purpura (ITP) is a predominant autoimmune disease, in which aberrant expression of miRNAs has been observed, suggesting that miRNAs are involved in its development. miRNAs could induce an imbalance in the T helper (Th)1/Th2 cell and Th17/Treg cell-related responses. Moreover, they could also cause alterations in Th9 and Th22 cell responses, and activate Tfh (T follicular helper) cell-dependent auto-reactive B cells, thus influencing megakaryogenesis. Herein, we summarize the role of immune-related miRNAs in ITP pathogenesis, and look forward to clinical applications. © 2021 Future Medicine Ltd.

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Style	Citing Format
MLA	Jafarzadeh A, et al.. "Dysregulated Expression of Mirnas in Immune Thrombocytopenia." Epigenomics, vol. 13, no. 16, 2021, pp. 1315-1325.
APA	Jafarzadeh A, Marzban H, Nemati M, Jafarzadeh S, Mahjoubintehran M, Hamblin MR, Mirzaei H, Mirzaei HR (2021). Dysregulated Expression of Mirnas in Immune Thrombocytopenia. Epigenomics, 13(16), 1315-1325.
Chicago	Jafarzadeh A, Marzban H, Nemati M, Jafarzadeh S, Mahjoubintehran M, Hamblin MR, Mirzaei H, Mirzaei HR. "Dysregulated Expression of Mirnas in Immune Thrombocytopenia." Epigenomics 13, no. 16 (2021): 1315-1325.
Harvard	Jafarzadeh A et al. (2021) 'Dysregulated Expression of Mirnas in Immune Thrombocytopenia', Epigenomics, 13(16), pp. 1315-1325.
Vancouver	Jafarzadeh A, Marzban H, Nemati M, Jafarzadeh S, Mahjoubintehran M, Hamblin MR, et al.. Dysregulated Expression of Mirnas in Immune Thrombocytopenia. Epigenomics. 2021;13(16):1315-1325.
BibTex	@article{ author = {Jafarzadeh A and Marzban H and Nemati M and Jafarzadeh S and Mahjoubintehran M and Hamblin MR and Mirzaei H and Mirzaei HR}, title = {Dysregulated Expression of Mirnas in Immune Thrombocytopenia}, journal = {Epigenomics}, volume = {13}, number = {16}, pages = {1315-1325}, year = {2021} }
RIS	TY - JOUR AU - Jafarzadeh A AU - Marzban H AU - Nemati M AU - Jafarzadeh S AU - Mahjoubintehran M AU - Hamblin MR AU - Mirzaei H AU - Mirzaei HR TI - Dysregulated Expression of Mirnas in Immune Thrombocytopenia JO - Epigenomics VL - 13 IS - 16 SP - 1315 EP - 1325 PY - 2021 ER -

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