Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent

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Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent Publisher

Almasi T¹ ; Gholipour N^{2, 3} ; Akhlaghi M⁴ ; Mokhtari Kheirabadi A⁴ ; Mazidi SM⁵ ; Hosseini SH⁶ ; Geramifar P⁴ ; Beiki D⁴ ; Rostampour N¹ ; Shahbazi Gahrouei D⁷

Source: International Journal of Polymeric Materials and Polymeric Biomaterials Published:2021

Abstract

Gallium-68 radiolabeled DOTA- acetyl-PAMAM coated iron oxide nanoparticles (NPs) were developed as dual-modality agents for PET-MR imaging. The increase in the chelator content, acetylation step, and radiolabeling condition had distinctive effects on the physical, biological, and radiochemical properties of NPs. The r2 relaxivity coefficient value of the NPs was 96.7 mM−1s−1. High accumulation of candidate NPs was in the liver and spleen and about 3.4% ID/g uptake (tissue sampling), and a distinctive uptake (PET-CT image) were observed in the tumor site. These NPs could be used as the dual-modality agent for the diagnosis of the tumors via PET-MR imaging. © 2020 Taylor & Francis Group, LLC.

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Style	Citing Format
MLA	Almasi T, et al.. "Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent." International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 70, no. 15, 2021, pp. 1077-1089.
APA	Almasi T, Gholipour N, Akhlaghi M, Mokhtari Kheirabadi A, Mazidi SM, Hosseini SH, Geramifar P, Beiki D, Rostampour N, Shahbazi Gahrouei D (2021). Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent. International Journal of Polymeric Materials and Polymeric Biomaterials, 70(15), 1077-1089.
Chicago	Almasi T, Gholipour N, Akhlaghi M, Mokhtari Kheirabadi A, Mazidi SM, Hosseini SH, Geramifar P, Beiki D, Rostampour N, Shahbazi Gahrouei D. "Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent." International Journal of Polymeric Materials and Polymeric Biomaterials 70, no. 15 (2021): 1077-1089.
Harvard	Almasi T et al. (2021) 'Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent', International Journal of Polymeric Materials and Polymeric Biomaterials, 70(15), pp. 1077-1089.
Vancouver	Almasi T, Gholipour N, Akhlaghi M, Mokhtari Kheirabadi A, Mazidi SM, Hosseini SH, et al.. Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent. International Journal of Polymeric Materials and Polymeric Biomaterials. 2021;70(15):1077-1089.
BibTex	@article{ author = {Almasi T and Gholipour N and Akhlaghi M and Mokhtari Kheirabadi A and Mazidi SM and Hosseini SH and Geramifar P and Beiki D and Rostampour N and Shahbazi Gahrouei D}, title = {Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent}, journal = {International Journal of Polymeric Materials and Polymeric Biomaterials}, volume = {70}, number = {15}, pages = {1077-1089}, year = {2021} }
RIS	TY - JOUR AU - Almasi T AU - Gholipour N AU - Akhlaghi M AU - Mokhtari Kheirabadi A AU - Mazidi SM AU - Hosseini SH AU - Geramifar P AU - Beiki D AU - Rostampour N AU - Shahbazi Gahrouei D TI - Development of Ga-68 Radiolabeled Dota Functionalized and Acetylated Pamam Dendrimer-Coated Iron Oxide Nanoparticles As Pet/Mr Dual-Modal Imaging Agent JO - International Journal of Polymeric Materials and Polymeric Biomaterials VL - 70 IS - 15 SP - 1077 EP - 1089 PY - 2021 ER -

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