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A Review on Application of Novel Solid Nanostructures in Drug Delivery Publisher



Faraji H1 ; Nedaeinia R2 ; Nourmohammadi E3 ; Malaekehnikouei B4 ; Sadeghnia HR5 ; Ziapour SP6 ; Sarkarizi HK7 ; Oskuee RK8
Authors
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Authors Affiliations
  1. 1. Department of Laboratory Science, Faculty of Para-medicine, Hormozgan University of Medical Science, Bandar Abbas, Iran
  2. 2. Deputy of Food and Drug, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Students Research Committee, Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  4. 4. Nanotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
  5. 5. Pharmacological Research Center of Medicinal Plants, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  6. 6. Department of Parasitology and Mycology, Amol Research Centre, Pasteur Institute of Iran, Amol, Iran
  7. 7. Department of Anatomical Sciences and Cell Biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  8. 8. Targeted Drug Delivery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Source: Journal of Nano Research Published:2018


Abstract

Nanotechnology as a multidisciplinary and scientific innovation plays an important role in numerous biomedical applications, such as molecular imaging, biomarkers and biosensors and also drug delivery. A wide range of studies have been conducted on using of nanoparticles for early diagnosis and targeted drug therapy of various diseases. In fact, the small size, customized surface, upgraded solubility, or multi-functionality of nanoparticles enabled them to interact with complex cellular functions in new ways which opened many doors and created new biomedical applications. These studies demonstrated that nanotechnology vehicles can formulate biological products effectively, and this nano-formulated products with a potent ability against different diseases, were represented to have better biocompatibility, bioaccessibility and efficacy, under in vitro and in vivo conditions. © 2018 Trans Tech Publications, Switzerland.
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