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Relationship Between Helicobacter Pylori Immunoglobulin G Antibody and Thrombotic Ischemic Stroke



Ashtari F1 ; Shayegannejad V1 ; Saberi A2
Authors
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Authors Affiliations
  1. 1. Department of Neurology, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran
  2. 2. Department of Neurology, School of Medicine, Guilan University of Medical Science, Guilan, Iran

Source: Acta Medica Iranica Published:2008

Abstract

Several studies have assessed association between Helicobacter pylori infection and fhrombotic ischemic stroke. This study was designed to investigate the association between this organism and ischemic strokes. Antibody against H. pylori (Hp IgG) was measured in 81 patients with stroke and 43 subjects without stroke. Hp IgG titer more than 20 u/ml was defined as positive. Hp IgG seropositivity was found in 67.4% of control subjects and 70.4% of cases (P = 0.838). The means of serum Hp IgG titers in control subjects and cases were 51.1859 u/ml and 50.1641 u/ml, respectively (P = 0.927). The difference between these 2 groups was not significant statistically. There wasn't any significant difference in seropositivity of Hp IgG between case and control subjects in men and women. It seems that H. pylori IgG titer hasn't a predictive role for thrombotic ischemic stroke. © 2008 Tehran University of Medical Sciences. All rights reserved.
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