Curcumin and Piperine in Covid-19: A Promising Duo to the Rescue? Publisher Pubmed

Summary: Curcumin-piperine shows promise for COVID-19 management with antiviral, anti-inflammatory, & antioxidant effects. #COVID19 #Curcumin

Miryan M^{1, 2} ; Soleimani D³ ; Askari G^{4, 5, 6} ; Jamialahmadi T^{7, 8} ; Guest PC⁹ ; Bagherniya M^{4, 5, 6} ; Sahebkar A^{10, 11, 12, 13}
Source: Advances in Experimental Medicine and Biology Published:2021

Abstract

COVID-19 is now pandemic throughout the world, and scientists are searching for effective therapies to prevent or treat the disease. The combination of curcumin and piperine is a potential option for the management of COVID-19 based on several mechanisms including antiviral, anti-inflammatory, immunomodulatory, antifibrotic, and antioxidant effects. Here, we describe the probable mechanism of curcumin-piperine against COVID-19. Administration of curcumin-piperine combination appears as a potential strategy to counterbalance the pathophysiological features of COVID-19 including inflammation. The optimal dose and duration of curcumin-piperine supplementation should be determined in the future. © 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.