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Echinophora Platyloba Dc. As a New Natural Antifungal Agent Publisher



Avijgan M1 ; Mahboubi M2
Authors
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Authors Affiliations
  1. 1. Department of Traditional Medicine, Isfahan University of Medical Sciences, Alzahrah Hospital, P.O. Box 795, Soffe St. Isfahan, Iran
  2. 2. Department of MICrobiology, Medicinal Plants, Research Center of Barij, P.O. Box 1187, Kashan, Iran

Source: Asian Pacific Journal of Tropical Disease Published:2015


Abstract

Echinophora platyloba DC. (Umbelliferae family) (E. platyloba) is a spiny plant with yellow flowers that in Iranian traditional medicine is used as an antifungal agent for preventing the dairy products and foods from fungi contaminations. This subject was the basis of an idea that has been supposed E. platyloba as an antifungal agent. This review investigates the studies that are designed on this idea. Also, it mentions other investigations that evaluate the other biological activities of this valuable plant. Literatures about E. platyloba were collected by electronic search and referred books on ethnopharmacology for receiving traditional records about this plant. Although, E. platyloba is a plant with many pharmacological effects but the main biological effect is their antifungal and synergistic effect with azole drugs against Candida albicans infections in vitro and in vivo studies. E. platyloba can be used as new candidates for treatment of Candida albicans infections. Other pharmacological effects should be more evaluated. Future studies should be directed on isolation and identification of antifungal sub-fractions by more precise investigations. © 2015 by the Asian Pacific Journal of Tropical Disease.
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