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Comparison of the Absorbed Dose for 99Mtc-Diethylenetriaminepentaacetic Acid and 99Mtc-Ethylenedicysteine Radiopharmaceuticals Using Medical Internal Radiation Dosimetry Publisher



Pirdamooie S1 ; Shanei A1 ; Moslehi M1
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Authors Affiliations
  1. 1. Department of Physic and Medical Engineering, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Medical Signals and Sensors Published:2015


Abstract

The aim of this study was the investigation of absorbed dose to the kidneys, spleen, and liver during technetium-99 m ethylene dicysteine and technetium-99 m diethylenetriaminepentaacetic acid (99mTc-EC and 99mTc-DTPA) kidney scan. Patients who had been prepared for the kidney scan, were divided into two groups (Groups 1 and 2). The first group (Group 1) and the second group (Group 2) received intravenous injection of 99mTc-EC and 99mTc-DTP, respectively. A certain amount of radiopharmaceuticals was injected into each patient and was immediately imaged with dual-head gamma camera to calculate the activity through the conjugated view method. Then, the doses of kidney, liver, and spleen were measured using medical internal radiation dosimetry method. Finally, absorbed dose of these organs was compared. Based on these different results (P < 0.05), organs absorbed dose was significantly less with radiopharmaceutical 99mTc-EC as compared with 99mTc-DTPA. © 2015, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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