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Gut Microbiota: A Perspective for Bipolar Disorders Publisher



Milani PG1 ; Nazari A2 ; Fallahasgari M3 ; Vadaei S4
Authors
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Authors Affiliations
  1. 1. Department of Food Science and Technology, Faculty of Nutrition & Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Department of Pediatric and Neonatal Nursing, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Food Science and Technology, Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Nursing, Golpayegan Branch, Islamic Azad University, Golpayegan, Iran

Source: Gastrointestinal Nursing Published:2024


Abstract

Psychiatric disorders, notably major depressive disorder and bipolar disorder, stand out as some of the most incapacitating conditions worldwide. Approximately 4.4% of the global population grapples with depression, making it a significant health concern. Bipolar disorder is distinguished by alternating episodes of depression and mania, interspersed with periods of normal mood. The beginning and progression of mental illnesses are becoming more influenced by the gut microbiome. Probiotics stand out as highly promising agents for modulating microbiota and have been studied for their potential to treat a broad range of illnesses, including obesity, type 2 diabetes, cancer, arthritis and mental health issues. This review delves into the connection between bipolar disorders and gut microbiota, elucidates the mechanisms through which probiotic bacteria alleviate bipolar symptoms and examines the potential of incorporating probiotic bacteria as an efficacious element in the therapy of bipolar disorder. © 2024 MA Healthcare Ltd.
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