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Prospective Epidemiological Research Studies in Iran (The Persian Cohort Study): Rationale, Objectives, and Design Publisher Pubmed



Poustchi H1 ; Eghtesad S1 ; Kamangar F2, 3 ; Etemadi A4 ; Keshtkar AA5 ; Hekmatdoost A6 ; Mohammadi Z1 ; Mahmoudi Z1 ; Shayanrad A1 ; Roozafzai F1 ; Sheikh M1 ; Jalaeikhoo A1 ; Somi MH7 ; Mansourghanaei F8 Show All Authors
Authors
  1. Poustchi H1
  2. Eghtesad S1
  3. Kamangar F2, 3
  4. Etemadi A4
  5. Keshtkar AA5
  6. Hekmatdoost A6
  7. Mohammadi Z1
  8. Mahmoudi Z1
  9. Shayanrad A1
  10. Roozafzai F1
  11. Sheikh M1
  12. Jalaeikhoo A1
  13. Somi MH7
  14. Mansourghanaei F8
  15. Najafi F9
  16. Bahramali E10
  17. Mehrparvar A11
  18. Ansarimoghaddam A12
  19. Enayati AA13
  20. Esmaeili Nadimi A14
  21. Rezaianzadeh A15
  22. Saki N16
  23. Alipour F17
  24. Kelishadi R18
  25. Rahimimovaghar A19
  26. Aminisani N20
  27. Boffetta P21
  28. Malekzadeh R3

Source: American Journal of Epidemiology Published:2018


Abstract

Noncommunicable diseases (NCDs) account for 76% of deaths in Iran, and this number is on the rise, in parallel with global rates. Many risk factors associated with NCDs are preventable; however, it is first necessary to conduct observational studies to identify relevant risk factors and the most appropriate approach to controlling them. Iran is a multiethnic country; therefore, in 2014 the Ministry of Health and Medical Education launched a nationwide cohort study - Prospective Epidemiological Research Studies in Iran (PERSIAN) - in order to identify the most prevalent NCDs among Iran's ethnic groups and to investigate effective methods of prevention. The PERSIAN study consists of 4 population-based cohorts; the adult component (the PERSIAN Cohort Study), described in this article, is a prospective cohort study including 180,000 persons aged 35-70 years from 18 distinct areas of Iran. Upon joining the cohort, participants respond to interviewer-administered questionnaires. Blood, urine, hair, and nail samples are collected and stored. To ensure consistency, centrally purchased equipment is sent to all sites, and the same team trains all personnel. Routine visits and quality assurance/control measures are taken to ensure protocol adherence. Participants are followed for 15 years postenrollment. The PERSIAN study is currently in the enrollment phase; cohort profiles will soon emerge. © The Author(s) 2018. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved.
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