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Recent Advances on Biomedical Applications of Gellan Gum: A Review Publisher Pubmed



Lalebeigi F1 ; Alimohamadi A2 ; Afarin S2 ; Aliabadi HAM3 ; Mahdavi M4 ; Farahbakhshpour F3 ; Hashemiaval N3 ; Khandani KK3 ; Eivazzadehkeihan R1 ; Maleki A1
Authors
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Authors Affiliations
  1. 1. Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran
  2. 2. School of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran
  3. 3. Medical Biotechnology Department, Biotechnology Research Center (BRC), Pasteur Institute of Iran (IPI), Tehran, Iran
  4. 4. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Carbohydrate Polymers Published:2024


Abstract

Gellan gum (GG) has attracted considerable attention as a versatile biopolymer with numerous potential biological applications, especially in the fields of tissue engineering, wound healing, and cargo delivery. Due to its distinctive characteristics like biocompatibility, biodegradability, nontoxicity, and gel-forming ability, GG is well-suited for these applications. This review focuses on recent research on GG-based hydrogels and biocomposites and their biomedical applications. It discusses the incorporation of GG into hydrogels for controlled drug release, its role in promoting wound healing processes, and its potential in tissue engineering for various tissues including bone, retina, cartilage, vascular, adipose, and cardiac tissue. It provides an in-depth analysis of the latest findings and advancements in these areas, making it a valuable resource for researchers and professionals in these fields. © 2024 Elsevier Ltd
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