Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and Their Application to Catalytic Oxygen Reduction and Cancer Imaging

Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and Their Application to Catalytic Oxygen Reduction and Cancer Imaging Publisher Pubmed

Molaabasi F^{1, 2} ; Sarparast M³ ; Shamsipur M⁴ ; Irannejad L² ; Moosavimovahedi AA⁵ ; Ravandi A⁶ ; Hajipour Verdom B⁷ ; Ghazfar R³

Show Affiliations

1. Department of Biomaterials and Tissue Engineering, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran
2. Department of Chemistry, Faculty of Basic Sciences, Tarbiat Modares University, Tehran, 14115-175, Iran
3. Department of Chemistry, Michigan State University, East Lansing, 48824-1322, MI, United States
4. Department of Chemistry, Faculty of Basic Sciences, Razi University, Kermanshah, Iran
5. Institute of Biochemistry and Biophysical Chemistry University, Tehran University, Tehran, Iran
6. Department of Chemistry, Faculty of Basic Sciences, Sharif University of Technology, Tehran, Iran
7. Department of Biophysics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, 14115-154, Iran

Source: Scientific Reports Published:2018

Abstract

Engineering hollow and porous platinum nanostructures using biomolecular templates is currently a significant focus for the enhancement of their facet-dependent optical, electronic, and electrocatalytic properties. However, remains a formidable challenge due to lack of appropriate biomolecules to have a structure-function relationship with nanocrystal facet development. Herein, human hemoglobin found to have facet-binding abilities that can control the morphology and optical properties of the platinum nanoclusters (Pt NCs) by regulation of the growth kinetics in alkaline media. Observations revealed the growth of unusual polyhedra by shape-directed nanocluster attachment along a certain orientation accompanied by Ostwald ripening and, in turn, yield well-dispersed hollow single-crystal nanotetrahedrons, which can easily self-aggregated and crystallized into porous and polycrystalline microspheres. The spontaneous, biobased organization of Pt NCs allow the intrinsic aggregation-induced emission (AIE) features in terms of the platinophilic interactions between Pt(II)-Hb complexes on the Pt(0) cores, thereby controlling the degree of aggregation and the luminescent intensity of Pt(0)@Pt(II)−Hb core−shell NCs. The Hb-Pt NCs exhibited high-performance electrocatalytic oxygen reduction providing a fundamental basis for outstanding catalytic enhancement of Hb-Pt catalysts based on morphology dependent and active site concentration for the four-electron reduction of oxygen. The as-prepared Hb-Pt NCs also exhibited high potential to use in cellular labeling and imaging thanks to the excellent photostability, chemical stability, and low cytotoxicity. © 2018, The Author(s).

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Style	Citing Format
MLA	Molaabasi F, et al.. "Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and Their Application to Catalytic Oxygen Reduction and Cancer Imaging." Scientific Reports, vol. 8, no. 1, 2018, pp. -.
APA	Molaabasi F, Sarparast M, Shamsipur M, Irannejad L, Moosavimovahedi AA, Ravandi A, Hajipour Verdom B, Ghazfar R (2018). Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and Their Application to Catalytic Oxygen Reduction and Cancer Imaging. Scientific Reports, 8(1), -.
Chicago	Molaabasi F, Sarparast M, Shamsipur M, Irannejad L, Moosavimovahedi AA, Ravandi A, Hajipour Verdom B, Ghazfar R. "Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and Their Application to Catalytic Oxygen Reduction and Cancer Imaging." Scientific Reports 8, no. 1 (2018): -.
Harvard	Molaabasi F et al. (2018) 'Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and Their Application to Catalytic Oxygen Reduction and Cancer Imaging', Scientific Reports, 8(1), pp. -.
Vancouver	Molaabasi F, Sarparast M, Shamsipur M, Irannejad L, Moosavimovahedi AA, Ravandi A, et al.. Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and Their Application to Catalytic Oxygen Reduction and Cancer Imaging. Scientific Reports. 2018;8(1):-.
BibTex	@article{ author = {Molaabasi F and Sarparast M and Shamsipur M and Irannejad L and Moosavimovahedi AA and Ravandi A and Hajipour Verdom B and Ghazfar R}, title = {Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and Their Application to Catalytic Oxygen Reduction and Cancer Imaging}, journal = {Scientific Reports}, volume = {8}, number = {1}, pages = {-}, year = {2018} }
RIS	TY - JOUR AU - Molaabasi F AU - Sarparast M AU - Shamsipur M AU - Irannejad L AU - Moosavimovahedi AA AU - Ravandi A AU - Hajipour Verdom B AU - Ghazfar R TI - Shape-Controlled Synthesis of Luminescent Hemoglobin Capped Hollow Porous Platinum Nanoclusters and Their Application to Catalytic Oxygen Reduction and Cancer Imaging JO - Scientific Reports VL - 8 IS - 1 SP - EP - PY - 2018 ER -

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