Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles in Different Tissues

Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles in Different Tissues Publisher Pubmed

Vakilighartavol R¹ ; Momtaziborojeni AA^{2, 3, 4} ; Vakilighartavol Z⁵ ; Aiyelabegan HT⁶ ; Jaafari MR⁷ ; Rezayat SM^{1, 8, 9} ; Arbabi Bidgoli S⁹

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1. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
2. Halal Research Center of IRI, FDA, Tehran, Iran
3. Nanotechnology Research Center, Bu-Ali Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran
4. Department of Medical Biotechnology, Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
5. Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
6. Department of Medical Biochemistry and Pharmacology, College of Pure and Applied Sciences, Kwara State University Malete, Nigeria
7. Department of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
8. Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
9. Department of Toxicologyâ€“Pharmacology, Faculty of Pharmacy, Pharmaceutical Science Branch, Islamic Azad University (IAUPS), Tehran, Iran

Source: Artificial Cells# Nanomedicine and Biotechnology Published:2020

Abstract

Superparamagnetic iron oxide nanoparticles (SPIONs) have been employed in several biomedical applications where they facilitate both diagnostic and therapeutic aims. Although the potential benefits of SPIONs with different surface chemistry and conjugated targeting ligands/proteins are considerable, complicated interactions between these nanoparticles (NPs) and cells leading to toxic impacts could limit their clinical applications. Hence, elevation of our knowledge regarding the SPION-related toxicity is necessary. Here, the present review article will consider current studies and compare the potential toxic effect of SPIONs with or without identical surface chemistries on different cell lines. It centers on cellular and molecular mechanisms underlying toxicity of SPIONs. Likewise, emphasis is being dedicated for toxicity of SPIONs in various cell lines, in vitro and animal models, in vivo. © 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

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Style	Citing Format
MLA	Vakilighartavol R, et al.. "Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles in Different Tissues." Artificial Cells# Nanomedicine and Biotechnology, vol. 48, no. 1, 2020, pp. 443-451.
APA	Vakilighartavol R, Momtaziborojeni AA, Vakilighartavol Z, Aiyelabegan HT, Jaafari MR, Rezayat SM, Arbabi Bidgoli S (2020). Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles in Different Tissues. Artificial Cells# Nanomedicine and Biotechnology, 48(1), 443-451.
Chicago	Vakilighartavol R, Momtaziborojeni AA, Vakilighartavol Z, Aiyelabegan HT, Jaafari MR, Rezayat SM, Arbabi Bidgoli S. "Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles in Different Tissues." Artificial Cells# Nanomedicine and Biotechnology 48, no. 1 (2020): 443-451.
Harvard	Vakilighartavol R et al. (2020) 'Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles in Different Tissues', Artificial Cells# Nanomedicine and Biotechnology, 48(1), pp. 443-451.
Vancouver	Vakilighartavol R, Momtaziborojeni AA, Vakilighartavol Z, Aiyelabegan HT, Jaafari MR, Rezayat SM, et al.. Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles in Different Tissues. Artificial Cells# Nanomedicine and Biotechnology. 2020;48(1):443-451.
BibTex	@article{ author = {Vakilighartavol R and Momtaziborojeni AA and Vakilighartavol Z and Aiyelabegan HT and Jaafari MR and Rezayat SM and Arbabi Bidgoli S}, title = {Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles in Different Tissues}, journal = {Artificial Cells# Nanomedicine and Biotechnology}, volume = {48}, number = {1}, pages = {443-451}, year = {2020} }
RIS	TY - JOUR AU - Vakilighartavol R AU - Momtaziborojeni AA AU - Vakilighartavol Z AU - Aiyelabegan HT AU - Jaafari MR AU - Rezayat SM AU - Arbabi Bidgoli S TI - Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles in Different Tissues JO - Artificial Cells# Nanomedicine and Biotechnology VL - 48 IS - 1 SP - 443 EP - 451 PY - 2020 ER -

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