Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer

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Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer Publisher

Modarres MP¹ ; Habibi MA^{2, 3} ; Pashaei MR⁴ ; Mohammadpour Y⁵ ; Jazi K³ ; Ahmadpour S⁴

Show Affiliations

1. Gastroentrology and Hepatology Diseases Research Center, Qom University of Medical Sciences, Qom, Iran
2. Iranian Tissue Bank and Research Center, Imam Khomeini Hospital, Tehran University of Medical Science, Tehran, Iran
3. Student Research Committee, Qom University of Medical Sciences, Qom, Iran
4. Patient Safety Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran
5. School of Medicine, Urmia University of Medical Sciences, Urmia, Iran

Source: Current Cancer Therapy Reviews Published:2025

Abstract

Colorectal cancer (CRC) is a commonly diagnosed cancer responsible for numerous deaths worldwide. In recent decades, technological advances implicated in considering the molecular pathways underlying CRC pathogenesis. Several investigations have identified various mechanisms involved in CRC and have paved the way for new therapeutics and early diagnosis. Gut microbiome play a crucial role in intestinal inflammation and can be associated with colitis colorectal cancer. In this review, we narrated the role of the microbiome population and their metabolome profile as a new screening method for early detection of CRC. © 2025 Bentham Science Publishers.

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Style	Citing Format
MLA	Modarres MP, et al.. "Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer." Current Cancer Therapy Reviews, vol. 21, no. 1, 2025, pp. 10-22.
APA	Modarres MP, Habibi MA, Pashaei MR, Mohammadpour Y, Jazi K, Ahmadpour S (2025). Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer. Current Cancer Therapy Reviews, 21(1), 10-22.
Chicago	Modarres MP, Habibi MA, Pashaei MR, Mohammadpour Y, Jazi K, Ahmadpour S. "Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer." Current Cancer Therapy Reviews 21, no. 1 (2025): 10-22.
Harvard	Modarres MP et al. (2025) 'Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer', Current Cancer Therapy Reviews, 21(1), pp. 10-22.
Vancouver	Modarres MP, Habibi MA, Pashaei MR, Mohammadpour Y, Jazi K, Ahmadpour S. Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer. Current Cancer Therapy Reviews. 2025;21(1):10-22.
BibTex	@article{ author = {Modarres MP and Habibi MA and Pashaei MR and Mohammadpour Y and Jazi K and Ahmadpour S}, title = {Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer}, journal = {Current Cancer Therapy Reviews}, volume = {21}, number = {1}, pages = {10-22}, year = {2025} }
RIS	TY - JOUR AU - Modarres MP AU - Habibi MA AU - Pashaei MR AU - Mohammadpour Y AU - Jazi K AU - Ahmadpour S TI - Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer JO - Current Cancer Therapy Reviews VL - 21 IS - 1 SP - 10 EP - 22 PY - 2025 ER -

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