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Remedial Effect of Boswellia Serrata on Thermal Burn Injuries Publisher



Sahinfard N1 ; Namjoo A2 ; Arami R1 ; Rafieian M3 ; Baradaran A4 ; Nasri H5 ; Shirzad H1 ; Nasri P4 ; Rafieiankopaei M1
Authors
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Authors Affiliations
  1. 1. Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
  2. 2. Pathology Department, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran
  3. 3. Isfahan Governor Office, Isfahan, Iran
  4. 4. Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department of Nephrology, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Shiraz E Medical Journal Published:2015


Abstract

Background: It has been shown that inflammation and insufficient blood vessel formation delay wound healing, whereas Boswellia serrata, besides anti-inflammatory activity, increases blood vessel formation. Objectives: This study was performed to investigate the effect of Boswellia serrata in promoting burn injuries healing in BALB/c mice. Materials and Methods: In this experimental study, a burn wound was created by placing a 1.5 cm2 hot plate on the back of animals. Fifty four mice were designated in four equal groups, counting 14 each. Three groups of animals were treated with Boswellia 2%, silver sulfadiazine and vaseline two times per day for 21 days. The fourth group represented the control group. The total percentage of wound healing and time required for complete healing were evaluated and compared between groups, using the ANOVA test. Results: Results showed that the effect of Boswellia on wound healing was statistically significant compared to the control group (P < 0.01). Conclusions: Boswellia serrata is clearly effective for burn injuries healing and might be used in patients with burn wound. © 2015, Shiraz University of Medical Sciences.
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