Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Preparation of Nanostructure Bioactive Diopside Scaffolds for Bone Tissue Engineering by Two Near Net Shape Manufacturing Techniques Publisher



Ghomi H1 ; Emadi R1 ; Javanmard SH2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran
  2. 2. Physiology Research Center, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran

Source: Materials Letters Published:2016


Abstract

Diopside has been recently investigated as a bioceramic with high mechanical and bioactivity properties, excellent biocompatibility, and appropriate degradation rate. This study has focused on fabrication of novel nanostructure diopside scaffolds by two near net shape manufacturing techniques (space holder and gelcasting methods) and comparison of their properties. The obtained scaffolds were characterized by means of X-ray Diffraction, transmission electron microscopy, scanning electron microscopy, Archimedes method, image analysis, and compression tests. The results demonstrated that both the space holder and gel casting methods led to fabrication of highly porous scaffolds with 82-85% total porosity. The prepared scaffolds were highly interconnected and had appropriate pore size (200-800 μm) and compressive strength (0.98±0.11-1.33±0.13 MPa). Therefore, the prepared nanostructure diopside scaffolds would be appropriate structure for use as bone substitute in bone tissue engineering. © 2016 Elsevier B.V. All rights reserved.
Related Docs
View other Related Docs
1. Fabrication and Characterization of Nanostructure Diopside Scaffolds Using the Space Holder Method: Effect of Different Space Holders and Compaction Pressures, Materials and Design (2016)
2. Tunable Cellular Interactions and Physical Properties of Nanofibrous Pcl-Forsterite: Gelatin Scaffold Through Sequential Electrospinning, Composites Science and Technology (2013)
3. Development of Porous Photopolymer Resin-Swcnt Produced by Digital Light Processing Technology Using for Bone Femur Application, Archives of Bone and Joint Surgery (2021)
4. A Femoral Shape Porous Scaffold Bio-Nanocomposite Fabricated Using 3D Printing and Freeze-Drying Technique for Orthopedic Application, Materials Chemistry and Physics (2022)
5. Evaluation of Physical, Mechanical and Biological Properties of Β-Tri-Calcium Phosphate/Poly-3-Hydroxybutyrate Nano Composite Scaffold for Bone Tissue Engineering Application, Materials Technology (2021)
6. Evaluation of the Effects of Nano-Tio2 on Bioactivity and Mechanical Properties of Nano Bioglass-P3hb Composite Scaffold for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2016)
7. Fabrication and Characterization of Hydroxyapatite-Coated Forsterite Scaffold for Tissue Regeneration Applications, Bulletin of Materials Science (2015)
8. Effects of Nano-Bioactive Glass on Structural, Mechanical and Bioactivity Properties of Poly (3-Hydroxybutyrate) Electrospun Scaffold for Bone Tissue Engineering Applications, Materials Technology (2019)
Experts (# of related papers)
View all Related Experts
Saeed Karbasi (73)
Mohammad Rafienia (43)
Other Related Docs
9. Natural Hydroxyapatite/Diopside Nanocomposite Scaffold for Bone Tissue Engineering Applications: Physical, Mechanical, Bioactivity and Biodegradation Evaluation, Materials Technology (2022)
10. Effect of Calcium Silicate Nanoparticle on Surface Feature of Calcium Phosphates Hybrid Bio-Nanocomposite Using for Bone Substitute Application, Powder Technology (2020)
11. A New Approach to Fabrication of Cs/Bg/Cnt Nanocomposite Scaffold Towards Bone Tissue Engineering and Evaluation of Its Properties, Applied Surface Science (2015)
12. Fabrication and Characterization of 3D-Printed Composite Scaffolds of Coral-Derived Hydroxyapatite Nanoparticles/Polycaprolactone/Gelatin Carrying Doxorubicin for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2024)
13. Synthesis and Characterization of Bioactive Glass Coated Forsterite Scaffold for Tissue Engineering Applications, Journal of Alloys and Compounds (2017)
14. Review of Recent Advances in Bone Scaffold Fabrication Methods for Tissue Engineering for Treating Bone Diseases and Sport Injuries, Tissue and Cell (2024)
15. Novel Electrospun Polyurethane Scaffolds Containing Bioactive Glass Nanoparticles, Bioinspired, Biomimetic and Nanobiomaterials (2020)
16. Mechanical Property of Poly (3-Hydroxybutyrate)/Bioglass Nanocomposite Scaffolds for Bone Tissue Engineering, IFMBE Proceedings (2010)
17. The Electrospun Poly(Ε-Caprolactone)/Fluoridated Hydroxyapatite Nanocomposite for Bone Tissue Engineering, Polymers for Advanced Technologies (2020)
18. Fabrication and Characterization of Novel Polyhydroxybutyrate-Keratin/Nanohydroxyapatite Electrospun Fibers for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2022)
19. Evaluation of Mechanical Property and Bioactivity of Nano-Bioglass 45S5 Scaffold Coated With Poly-3-Hydroxybutyrate, Journal of Materials Science: Materials in Medicine (2015)
20. Fabrication of 3D Porous Polyurethane-Graphene Oxide Scaffolds by a Sequential Two-Step Processing for Non-Load Bearing Bone Defects, Physica Scripta (2024)
21. Comparison of Acellular and Cellular Bioactivity of Poly 3-Hydroxybutyrate/Hydroxyapatite Nanocomposite and Poly 3-Hydroxybutyrate Scaffolds, Biotechnology and Bioprocess Engineering (2013)
22. Fabrication and Characterization of Polyphosphazene/Calcium Phosphate Scaffolds Containing Chitosan Microspheres for Sustained Release of Bone Morphogenetic Protein 2 in Bone Tissue Engineering, Tissue Engineering and Regenerative Medicine (2017)
23. Mechanical and Cytotoxicity Evaluation of Nanostructured Hydroxyapatite-Bredigite Scaffolds for Bone Regeneration, Materials Science and Engineering C (2016)
24. Evaluation of Physical, Mechanical and Biological Properties of Bioglass/Titania Scaffold Coated With Poly (3-Hydroxybutyrate)-Chitosan for Bone Tissue Engineering Applications, Materials Technology (2020)
25. Global Criterion Optimization Method for Improving the Porosity of Porous Scaffolds Containing Magnetic Nanoparticles: Fabrication and Finite Element Analysis, Materials Science and Engineering: B (2023)
26. Evaluation of Mg63 Cells Behavior With Electrospun Nanocomposite Scaffolds of Polycaprolactone and Carbon Quantum Dot Containing Captopril for Bone Tissue Engineering, Journal of Knowledge and Health in Basic Medical Sciences (2020)
27. Morphology and Degradation of Poly (3-Hydroxybutyrate)/ Nano-Hydroxyapatite Scaffold Used in Tissue Engineering, Journal of Isfahan Medical School (2012)
28. The Effect of Porosity on the Mechanical Properties of Porous Titanium Scaffolds: Comparative Study on Experimental and Analytical Values, Materials Research Express (2018)
29. Mechanical Evaluation of Nhap Scaffold Coated With Poly-3-Hydroxybutyrate for Bone Tissue Engineering, Journal of Nanoscience and Nanotechnology (2013)
30. Evaluation of the Effects of Starch on Polyhydroxybutyrate Electrospun Scaffolds for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2021)
31. Surface Modification of Additive Manufactured Ti6al4v Scaffolds With Gelatin/Alginate- Igf-1 Carrier: An Effective Approach for Healing Bone Defects, International Journal of Biological Macromolecules (2024)
32. A Ternary Nanocomposite Fibrous Scaffold Composed of Poly(Ε-Caprolactone)/Gelatin/Gehlenite (Ca2al2sio7): Physical, Chemical, and Biological Properties in Vitro, Polymers for Advanced Technologies (2021)
33. 3D Printed Polycaprolactone/Gelatin/Ordered Mesoporous Calcium Magnesium Silicate Nanocomposite Scaffold for Bone Tissue Regeneration, Journal of Materials Science: Materials in Medicine (2024)
34. Fabrication and Characterization of 3D Nanostructured Polycaprolactone-Gelatin/Nanohydroxyapatite-Nanoclay Scaffolds for Bone Tissue Regeneration, Journal of Polymers and the Environment (2024)
35. Enhancing the Biological Characteristics of Aminolysis Surface-Modified 3D Printed Nanocomposite Polycaprolactone/Nanohydroxyapatite Scaffold Via Gelatin Biomacromolecule Immobilization: An in Vitro and in Vivo Study, Colloids and Surfaces B: Biointerfaces (2025)
36. Physical and Mechanical Properties of a Poly-3-Hydroxybutyratecoated Nanocrystalline Hydroxyapatite Scaffold for Bone Tissue Engineering, Journal of Porous Materials (2012)
37. Preparation of a Novel Biodegradable Nanocomposite Scaffold Based on Poly (3-Hydroxybutyrate)/Bioglass Nanoparticles for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2010)
38. Synthetic Electrospun Nanofibers As a Supportive Matrix in Osteogenic Differentiation of Induced Pluripotent Stem Cells, Journal of Biomaterials Science, Polymer Edition (2022)
39. Incorporation of Nanohydroxyapatite and Vitamin D3 Into Electrospun Pcl/Gelatin Scaffolds: The Influence on the Physical and Chemical Properties and Cell Behavior for Bone Tissue Engineering, Polymers for Advanced Technologies (2018)
40. Nanobiomaterials in Periodontal Tissue Engineering, Nanobiomaterials in Hard Tissue Engineering: Applications of Nanobiomaterials (2016)
41. Synergetic Effect of Bioglass and Nano Montmorillonite on 3D Printed Nanocomposite of Polycaprolactone/Gelatin in the Fabrication of Bone Scaffolds, International Journal of Biological Macromolecules (2024)
42. Evaluation of Physical and Mechanical Properties of Fi-Tri-Calcium Phosphate/Poly-3-Hydroxybutyrate Nanocomposite Scaffold for Bone Tissue Engineering Application, Scientia Iranica (2017)
43. Electrospun Poly(Hydroxybutyrate)/Chitosan Blend Fibrous Scaffolds for Cartilage Tissue Engineering, Journal of Applied Polymer Science (2016)
44. Biological Evaluation and Osteogenic Potential of Polyhydroxybutyrate-Keratin/Al2o3 Electrospun Nanocomposite Scaffold: A Novel Bone Regeneration Construct, International Journal of Biological Macromolecules (2023)
45. Cytocompatibility and Antibacterial Properties of Coaxial Electrospun Nanofibers Containing Ciprofloxacin and Indomethacin Drugs, Polymers (2022)
46. Gehlenite Nanobioceramic: Sol-Gel Synthesis, Characterization, and in Vitro Assessment of Its Bioactivity, Materials Letters (2018)
47. Polycaprolactone/Gelatin/Hydroxyapatite Nanocomposite Scaffold Seeded With Stem Cells From Human Exfoliated Deciduous Teeth to Enhance Bone Repair: In Vitro and in Vivo Studies, Materials Technology (2022)
48. Controlled Gentamicin- Strontium Release As a Dual Action Bone Agent: Combination of the Porous Titanium Scaffold and Biodegradable Polymers, Journal of Alloys and Compounds (2017)
49. Preparation and Characterization of 3D Nanocomposite Scaffold From Bioactive Glass/Β-Tricalcium Phosphate Via Robocasting Method for Bone Tissue Engineering, Journal of Non-Crystalline Solids (2022)
50. Multi-Cellular Tumor Spheroids Formation of Colorectal Cancer Cells on Gelatin/Plcl and Collagen/Plcl Nanofibrous Scaffolds, European Polymer Journal (2019)