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Regional Disparities in Cancer Survival in Iran: Insight From a National Surveillance of Cancer Survival in Iran (Irancansurv) Publisher Pubmed



Nemati S1 ; Saeedi E1, 2 ; Lotfi F1 ; Nahvijou A1 ; Pirnejad H3 ; Cheraghi M4 ; Rezaeianzadeh A5 ; Dolatkhah R6 ; Bazarafshan A7 ; Golpazir A8 ; Yaghoobiashrafi M9 ; Abdi S1 ; Alvand S10 ; Ravankhah Z11 Show All Authors
Authors
  1. Nemati S1
  2. Saeedi E1, 2
  3. Lotfi F1
  4. Nahvijou A1
  5. Pirnejad H3
  6. Cheraghi M4
  7. Rezaeianzadeh A5
  8. Dolatkhah R6
  9. Bazarafshan A7
  10. Golpazir A8
  11. Yaghoobiashrafi M9
  12. Abdi S1
  13. Alvand S10
  14. Ravankhah Z11
  15. Mohebbi E1, 12
  16. Khosravi A13
  17. Etemadi A14
  18. Sheikh M15
  19. Roshandel G16
  20. Ghanbarimotlagh A17
  21. Partovipour E18
  22. Najafi F19
  23. Malekzadeh R20
  24. Mohagheghi MA1
  25. Zendehdel K1

Source: Cancer Epidemiology Published:2023


Abstract

Background and objectives: We aimed to investigate geographical disparity in cancer survival in 9 provincial population-based cancer registries in Iran from 2015 to 2016. Material and method: In the current study, data from 90,862 adult patients (aged >15 years) diagnosed with cancer were retrieved from 9 population-based cancer registries across Iran. Five-year survival rates were estimated by applying relative survival approaches. We also applied the international cancer survival standard weights for age standardization. Finally, we calculated the excess hazard ratio (EHR) for each province adjusted for age, sex, and cancer sites to estimate the excess hazard ratio of mortality compared to the capital province (Tehran). Results: The largest gap in survival was observed in more curable cancer types, including melanoma (41.4%), ovary (32.3%), cervix (35.0%), prostate (26.7%), and rectum (21.4%), while the observed geographical disparity in lethal cancers such as lung, brain, stomach, and pancreas was less than 15%. Compared to Tehran, we found the highest excess hazard of death in Western Azerbaijan (EHR=1.60, 95% CI 1.51, 1.65), Kermanshah (EHR=1.52, 95% CI=1.44, 1.61), and Kerman (EHR=1.46, 95% CI=1.38, 1.53). The hazard ratio of death was almost identical in Isfahan (EHR=1.04, 95% CI=1.03, 1.06) and Tehran provinces. Conclusion: Provinces with higher HDI had better survival rates. IRANCANSURV study showed regional disparities in cancer survival in Iran. Cancer patients in provinces with a higher Human Development Index (HDI) had a higher survival rate and lived longer compared to the patients in provinces with medium and low HDI regions. © 2023 Elsevier Ltd
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