Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Poly(Methyl Methacrylate) Bone Cement, Its Rise, Growth, Downfall and Future Publisher

Summary: A study suggests adding hydroxyapatite to bone cement may improve bone repair by enhancing strength and bioactivity, potentially speeding up recovery. #BoneHealth #MedicalResearch

Soleymani Eil Bakhtiari S1 ; Bakhsheshirad HR1 ; Karbasi S2 ; Tavakoli M3 ; Hassanzadeh Tabrizi SA1 ; Ismail AF4 ; Seifalian A5 ; Ramakrishna S6 ; Berto F7
Authors

Source: Polymer International Published:2021


Abstract

Poly(methyl methacrylate) (PMMA)-based bone cements (BCs) can be defined as a family of materials that consist of powder and liquid phases which after mixing form a plastic paste that can self-set once implanted in the human body. PMMA-based BCs are easily molded and adapted to complex bone cavities or used in orthodontic applications to restore dental damage. The main advantages of the use of cement are the excellent primary fixation between bone and implant and, therefore, the faster recovery of the patient. Despite the initial success rate of implant fixation with BCs, they have some disadvantages such as local tissue damage due to exothermic polymerization reactions, mechanical mismatch between native bone and cement, lack of bone regeneration and bioactivity and poor mechanical properties which may cause the failure of the BCs. BCs are still considered as a top option for bone repair. Due to the disadvantages highlighted, research has focused on alternative materials used with PMMA-based BCs. This review aims to critically review the BCs and emerging materials used in combination with PMMA-based BCs. These materials include titania, apatite–wollastonite (A-W), glass ceramic (GC) and hydroxyapatite (HA). The review discusses the properties of these materials and their pathway to clinical study. Among the various kinds of reinforcement, HA has been extensively used. So, in this review, we compare the effects of HA as reinforcement in PMMA-based BCs. Upcoming study of PMMA-based BCs should concentrate on trialing combinations of these reinforcing agents as this might improve beneficial characteristics. © 2020 Society of Industrial Chemistry. © 2020 Society of Industrial Chemistry
Related Docs
View other Related Docs
1. Poly(Methyl Methacrylate)-Based Composite Bone Cements With Different Types of Reinforcement Agents, Encyclopedia of Materials: Composites (2021)
2. Evaluation of the Effects of Chitosan/Multiwalled Carbon Nanotubes Composite on Physical, Mechanical and Biological Properties of Polymethyl Methacrylate-Based Bone Cements, Materials Technology (2020)
3. Incorporation of Chitosan/Graphene Oxide Nanocomposite in to the Pmma Bone Cement: Physical, Mechanical and Biological Evaluation, International Journal of Biological Macromolecules (2020)
Experts (# of related papers)
View all Related Experts
Saeed Karbasi (5)
Farahnaz Nejatidanesh (2)
Poly(Methyl Methacrylate) Bone Cement, Its Rise, Growth, Downfall and Future
Other Related Docs
4. Polymethyl Methacrylate-Based Bone Cements Containing Carbon Nanotubes and Graphene Oxide: An Overview of Physical, Mechanical, and Biological Properties, Polymers (2020)
5. Retention of Implant-Supported Zirconium Oxide Ceramic Restorations Using Different Luting Agents, Clinical Oral Implants Research (2013)
6. A Porous Polymeric–Hydroxyapatite Scaffold Used for Femur Fractures Treatment: Fabrication, Analysis, and Simulation, European Journal of Orthopaedic Surgery and Traumatology (2020)
7. Synthesis and Characterization of Bioactive Glass Coated Forsterite Scaffold for Tissue Engineering Applications, Journal of Alloys and Compounds (2017)
8. Improving Physicochemical, Mechanical, and Biological Properties of a Porous Polyvinyl Alcohol/Chitosan Matrix Via Modification With Magnesium and Silicon Agents, Nanomedicine Journal (2025)
9. Thermo-Responsive Hydrogels Based on Methylcellulose/Persian Gum Loaded With Taxifolin Enhance Bone Regeneration: An in Vitro/In Vivo Study, Cellulose (2022)
10. Dentin Extracellular Matrix Loaded Bioactive Glass/Gelma Support Rapid Bone Mineralization for Potential Pulp Regeneration, International Journal of Biological Macromolecules (2023)
11. Review of Recent Advances in Bone Scaffold Fabrication Methods for Tissue Engineering for Treating Bone Diseases and Sport Injuries, Tissue and Cell (2024)
12. Graphene Oxide-Encapsulated Baghdadite Nanocomposite Improved Physical, Mechanical, and Biological Properties of a Vancomycin-Loaded Pmma Bone Cement, Journal of Biomaterials Science, Polymer Edition (2024)
13. Effect of Ceramic Thickness on the Polymerization Quality and Film Thickness of Dual-Polymerizing Versus Heated Light-Polymerizing Adhesive Cement, Journal of Prosthetic Dentistry (2024)
14. Layered Scaffolds in Periodontal Regeneration, Journal of Oral Biology and Craniofacial Research (2022)
15. Combinatorial Fluorapatite-Based Scaffolds Substituted With Strontium, Magnesium and Silicon Ions for Mending Bone Defects, Materials Science and Engineering C (2021)
16. Effects of Doping Metal Nanoparticles in Hydroxyapatite in Improving the Physical and Chemical Properties of Dental Implants, Nanomedicine Research Journal (2021)
17. Application of Cellulose Scaffolds for Drug Delivery and Micrornas in Bone Formation and Bone Defect Repair, Regenerative Engineering and Translational Medicine (2025)
18. Osteoconductive Visible Light-Crosslinkable Nanocomposite for Hard Tissue Engineering, Colloids and Surfaces A: Physicochemical and Engineering Aspects (2022)
19. Development of Porous Photopolymer Resin-Swcnt Produced by Digital Light Processing Technology Using for Bone Femur Application, Archives of Bone and Joint Surgery (2021)
20. Resin Cement Selection for Different Types of Fixed Partial Coverage Restorations: A Narrative Systematic Review, Clinical and Experimental Dental Research (2023)