Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Effects of Doping Metal Nanoparticles in Hydroxyapatite in Improving the Physical and Chemical Properties of Dental Implants Publisher



Tosan F1 ; Fathi AH2 ; Yari A3 ; Rahnama N4 ; Sakhaei D5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Semnan University of Medical Sciences, Semnan, Iran
  2. 2. Dental Material Research Center, Department of Prosthodontics, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Dental Research Center, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. School of Medicine, Semnan University of Medical Sciences, Semnan, Iran
  5. 5. School of Medicine, Sari branch, Islamic Azad University, Sari, Iran

Source: Nanomedicine Research Journal Published:2021


Abstract

There are strong proofs for the therapeutic benefits of dental implants utility in regards to the replacement of dental elements throughout the treatment of complete or partial edentulism. Many materials were used for the manufacturing of dental implants throughout the history of this field. Hydroxyapatite is one of the popular structures due to being highly biocompatible, however, its poor stability fences its application. Therefore, the approach of doping with other structures, such as metal nanoparticles, can be proposed to circumvent this obstacle. Various metal nanoparticles are exerted in the role of dopants, which include manganese, silver, magnesium, cobalt, zinc, silicon, strontium, lithium,cerium, yttrium, neodymium, hafnium, erbium, and cadmium. According to available evidences, the doping of metal nanoparticles with hydroxyapatite can improve the obtained mechanical stability, biocompatibility, osteoinductivity, osteoinductivity, the integrity of bone tissues, antibacterial properties, and other features, which is effective in increasing their potential applications. Apart from the offered benefits, the process of doping metal nanoparticles in dental implants is still in its infancy and struggles with several challenges. © 2021 Tehran University of Medical Sciences. All right reserved.
Related Docs
View other Related Docs
1. Nanoparticles to Overcome Bacterial Resistance in Orthopedic and Dental Implants, Nanomedicine Research Journal (2022)
2. Preparation and Characterization of Hydroxyapatite Nanoparticles Doped With Nickel, Tin, and Molybdate Ions for Their Antimicrobial Effects, Drug Development and Industrial Pharmacy (2023)
3. Biodegradable Magnesium Bone Implants Coated With a Novel Bioceramic Nanocomposite, Materials (2020)
4. Modified Mechanical Coating Technique for the Preparation of Nanohydroxyapatite Coated Ti–6Al–4V Dental Implants, Protection of Metals and Physical Chemistry of Surfaces (2020)
5. Synthesis and Characterization of Nanosized Magnesium-Doped Fluorapatite Powder and Coating for Biomedical Application, Journal of Sol-Gel Science and Technology (2015)
6. Structural Comparison of Natural and Synthetic Nanocrystalline Hydroxyapatite, Journal of Isfahan Medical School (2012)
7. An in Vitro Evaluation of Novel Nha/Zircon Plasma Coating on 316L Stainless Steel Dental Implant, Progress in Natural Science: Materials International (2014)
8. Fabrication and Characterization of 3D-Printed Composite Scaffolds of Coral-Derived Hydroxyapatite Nanoparticles/Polycaprolactone/Gelatin Carrying Doxorubicin for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2024)
Experts (# of related papers)
View all Related Experts
Omid Savabi (14)
Saeed Karbasi (11)
Other Related Docs
9. Preparation and Biocompatibility Evaluation of Bioactive Glass-Forsterite Nanocomposite Powder for Oral Bone Defects Treatment Applications, Materials Science and Engineering C (2015)
10. Recent Advances on Akermanite Calcium-Silicate Ceramic for Biomedical Applications, International Journal of Applied Ceramic Technology (2021)
11. Nanobiomaterials in Periodontal Tissue Engineering, Nanobiomaterials in Hard Tissue Engineering: Applications of Nanobiomaterials (2016)
12. In Vivo Biocompatibility of Mg Implants Surface Modified by Nanostructured Merwinite/Peo, Journal of Materials Science: Materials in Medicine (2015)
13. Preparation and Bioactivity Evaluation of Bone-Like Hydroxyapatite Nanopowder, Journal of Materials Processing Technology (2008)
14. Characterization and in Vitro Evaluation of Nanostructure Barium Titanate Coating on Ti6al4v, Journal of Ceramic Processing Research (2016)
15. Sodium Alginate/Magnesium Oxide Nanocomposite Scaffolds for Bone Tissue Engineering, Polymers for Advanced Technologies (2018)
16. Biodegradable Nanocomposite Coatings Accelerate Bone Healing: In Vivo Evaluation, Dental Research Journal (2015)
17. In Vitro Study of a Novel Multi-Substituted Hydroxyapatite Nanopowder Synthesized by an Ultra-Fast, Efficient and Green Microwave-Assisted Method, Materials Science and Engineering C (2020)
18. Fabrication of Elastin Additive on Polymethyl Methacrylate and Hydroxyapatite-Based Bioactive Bone Cement, Materials Chemistry and Physics (2022)
19. In Vitro Characterisation of a Sol–Gel Derived in Situ Silica-Coated Silicate and Carbonate Co-Doped Hydroxyapatite Nanopowder for Bone Grafting, Materials Science and Engineering C (2017)
20. Polycaprolactone/Gelatin/Hydroxyapatite Nanocomposite Scaffold Seeded With Stem Cells From Human Exfoliated Deciduous Teeth to Enhance Bone Repair: In Vitro and in Vivo Studies, Materials Technology (2022)
21. Synthesis and Characterization of Fluorapatite Nanoparticles Via a Mechanochemical Method, Journal of Cluster Science (2015)
22. Application of Magnesium Oxide Nanoparticles in Dentistry: A Literature Review, European Journal of General Dentistry (2023)
23. Synthesis, Characterization, in Vitro Bioactivity and Biocompatibility Evaluation of Hydroxyapatite/Bredigite (Ca7mgsi4o16) Composite Nanoparticles, JOM (2016)
24. Comparative Evaluation of Hydroxyapatite and Nano-Bioglass in Two Forms of Conventional Micro-And Nano-Particles in Repairing Bone Defects (An Animal Study), Indian Journal of Dental Research (2015)
25. Effect of Calcium Silicate Nanoparticle on Surface Feature of Calcium Phosphates Hybrid Bio-Nanocomposite Using for Bone Substitute Application, Powder Technology (2020)
26. In Vivo Assessments of Bioabsorbable Az91 Magnesium Implants Coated With Nanostructured Fluoridated Hydroxyapatite by Mao/Epd Technique for Biomedical Applications, Materials Science and Engineering C (2015)
27. Effect of Mg Content on the Bioactivity and Biocompatibility of Mg-Substituted Fluorapatite Nanopowders Fabricated Via Mechanical Activation, Materials Science and Engineering C (2016)
28. Calcitonin-Loaded Octamaleimic Acid–Silsesquioxane Nanoparticles in Hydrogel Scaffold Support Osteoinductivity in Bone Regeneration, Pharmaceutical Development and Technology (2021)
29. Natural Hydroxyapatite/Diopside Nanocomposite Scaffold for Bone Tissue Engineering Applications: Physical, Mechanical, Bioactivity and Biodegradation Evaluation, Materials Technology (2022)
30. Biodegradation Assessment of Nanostructured Fluoridated Hydroxyapatite Coatings on Biomedical Grade Magnesium Alloy, Ceramics International (2014)
31. Simultaneous Structural and Surface Modifications of Nanophase Hydroxyapatite for Improving Its Dissolution and Bioactivity, Ceramics International (2016)
32. Comparing Nanostructured Hydroxyapatite Coating on Az91 Alloy Samples Via Sol-Gel and Electrophoretic Deposition for Biomedical Applications, IEEE Transactions on Nanobioscience (2014)
33. Biodegradable Magnesium Alloy Coated by Fluoridated Hydroxyapatite Using Mao/Epd Technique, Surface Engineering (2014)
34. Improvement of in Vitro Behavior of an Mg Alloy Using a Nanostructured Composite Bioceramic Coating, Journal of Materials Science: Materials in Medicine (2018)
35. Synthesis, Characterization and Bioactivity Evaluation of Nano-Structured Hydroxyapatite, WIT Transactions on Engineering Sciences (2009)
36. Improvement in Osseointegration of Tricalcium Phosphate-Zircon for Orthopedic Applications: An in Vitro and in Vivo Evaluation, Medical and Biological Engineering and Computing (2020)
37. Synthesis and Dissolution Behavior of Nanosized Silicon and Magnesium Co-Doped Fluorapatite Obtained by High Energy Ball Milling, Ceramics International (2014)
38. Magnesium/Nano-Hydroxyapatite Porous Biodegradable Composite for Biomedical Applications, Materials Research Express (2019)
39. The Antimicrobial Effect of Doxycycline and Doped Zno in Tio2 Nanotubes Synthesized on the Surface of Orthodontic Mini-Implants, APOS Trends in Orthodontics (2022)
40. Mechanical Evaluation of Nhap Scaffold Coated With Poly-3-Hydroxybutyrate for Bone Tissue Engineering, Journal of Nanoscience and Nanotechnology (2013)
41. The Influence of Bioglass Nanoparticles on the Biodegradation and Biocompatibility of Poly (3-Hydroxybutyrate) Scaffolds, International Journal of Artificial Organs (2012)
42. Effects of Bioglass Nanoparticles on Bioactivity and Mechanical Property of Poly(3-Hydroxybutirate) Scaffolds, Scientia Iranica (2013)
43. Electrophoretic Deposition of Nanostructured Hydroxyapatite Coating on Az91 Magnesium Alloy Implants With Different Surface Treatments, Applied Surface Science (2013)
44. Fabrication and Characterization of Reinforced Glass Ionomer Cement by Zinc Oxide and Hydroxyapatite Nanoparticles, Heliyon (2024)
45. Novel Nanocomposite Coating for Dental Implant Applications in Vitro and in Vivo Evaluation, Journal of Materials Science: Materials in Medicine (2012)
46. Fabrication and Evaluation of Amalgam/Nano Hydroxyapatite Composites for Dental Restoration, Materials Research Express (2018)
47. Coating of Biodegradable Magnesium Alloy Bone Implants Using Nanostructured Diopside (Camgsi 2 O 6 ), Applied Surface Science (2014)
48. Electrophoretic-Deposited Hydroxyapatite-Copper Nanocomposite As an Antibacterial Coating for Biomedical Applications, Surface and Coatings Technology (2017)
49. Magnesium/Nano-Hydroxyapatite Composite for Bone Reconstruction: The Effect of Processing Method, Journal of Bionic Engineering (2020)
50. Investigation on Bioactivity and Cytotoxicity of Mesoporous Nano-Composite Mcm-48/Hydroxyapatite for Ibuprofen Drug Delivery, Ceramics International (2014)