Tehran University of Medical Sciences

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Faculty Members have conducted research related to the The Role of Sleep Deprivation in Streptozotocin-Induced Alzheimer’S Disease-Like Sporadic Dementia in Rats With Respect to the Serum Level of Oxidative and Inflammatory Markers
Gholamali Kardar
Gholamali Kardar

Professor of Molecular Genetics

Immunology, Asthma & Allergy Research Center

Tehran University of Medical Sciences

All Documents
1. Crispr/Cas System: A Powerful Strategy to Improve Monogenic Human Diseases As Therapeutic Delivery; Current Applications and Challenges, Current Gene Therapy (2025)
2. An Updated Review of Interleukin-2 Therapy in Cancer and Autoimmune Diseases, Journal of Interferon and Cytokine Research (2024)
3. Competitive Effect of Overexpressed C-Terminal of Snail-1 (Csnail) in Control of the Growth and Metastasis of Melanoma Cells, Recent Patents on Anti-Cancer Drug Discovery (2024)
4. Evaluation of Metastasis Inhibition by Abd-Il-2 Compared to Human Il-2 in a Breast Cancer Mouse Model, Iranian Journal of Immunology (2024)
5. Expression and Synthesis of Recombinant Human Coagulation Factor Viii Using a Cell-Free Expression System, Journal of Babol University of Medical Sciences (2024)
6. Increased Expression Level of Human Blood Clotting Factor Viii Using Ns0 Cell Line As a Host Cells, Iranian Journal of Biotechnology (2024)
7. Revisiting of Properties and Modified Polyethylenimine-Based Cancer Gene Delivery Systems, Biochemical Genetics (2024)
8. The Effects of Staphylococcus Aureus Protein a (Spa) on the Expression of Inflammatory Cytokines in Autoimmune Patients and Their Probable Immune Response Modulation Mechanisms, Cytokine (2024)
9. The Evaluation of the N-Cadherin Promoter’S Ability to Block Emt by Specific Expression of Diphtheria Toxin in Emt-Induced A549 Cell Lines, Iranian Journal of Allergy# Asthma and Immunology (2024)
10. Allergen-Specific Immunotherapy by Recombinant Der P1 Allergen-Derived Peptide-Based Vaccine in an Allergic Mouse Model, Immunity# Inflammation and Disease (2023)
11. Reversing T Cell Exhaustion by Converting Membrane Pd-1 to Its Soluble Form in Jurkat Cells; Applying the Crispr/Cas9 Exon Skipping Strategy, Cell Journal (2023)
12. The Immunostimulant Effects of the Rice Ragged Stunt Virus Genome on the Growth and Metastasis of Breast Cancer in Mouse Model, International Immunopharmacology (2023)
13. The Trend of Crispr-Based Technologies in Covid-19 Disease: Beyond Genome Editing, Molecular Biotechnology (2023)
14. Unfavorable Left Ventricular Remodeling Due to Experience of Chronic Sleep Restriction After Myocardial Infarction: The Role of Matrix Metalloproteinases & Oxidative Stress, Cardiovascular Pathology (2023)
15. A Comprehensive Overview of Allergen-Specific Immunotherapy Types, Recombinant and Natural Extract Allergens in the Diagnosis and Treatment of Allergies, Iranian Journal of Allergy# Asthma and Immunology (2022)
16. Cobalt Chloride-Induced Hypoxia Can Lead Skbr3 and Hek293t Cell Lines Toward Epithelial-Mesenchymal Transition, Iranian Journal of Allergy# Asthma and Immunology (2022)
17. Covid-19: A Systematic Review and Update on Prevention, Diagnosis, and Treatment, MedComm (2022)
18. Epitope Mapping of Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Receptor Binding Domain-Specific Monoclonal Antibodies, Frontiers in Medicine (2022)
19. Identification of Immunodominant Epitopes on Nucleocapsid and Spike Proteins of the Sars-Cov-2 in Iranian Covid-19 Patients, Pathogens and Disease (2022)
20. Differential Antibody Response to Sars-Cov-2 Antigens in Recovered and Deceased Iranian Covid-19 Patients, Viral Immunology (2021)
21. Does Prior Immunization With Measles, Mumps, and Rubella Vaccines Affect the Antibody Response to Covid-19 Antigens?, Iranian Journal of Immunology (2021)
22. Fam72a Antagonizes Ung2 to Promote Mutagenic Repair During Antibody Maturation, Nature (2021)
23. Identification of A 53 Kda Protein, As A New High Molecular Weight Allergen From Fraxinus Excelsior (Ash) Pollen, Allergo Journal International (2020)
24. Induction of Humoral Immune Responses and Inhibition of Metastasis in Mice by a Vegf Peptide-Based Vaccine, Iranian Journal of Basic Medical Sciences (2020)
25. Induction of Humoral Immune Responses and Inhibition of Metastasis in Mice by a Vegf Peptide-Based Vaccine, Iranian Journal of Basic Medical Sciences (2020)
26. Overexpression of Bhlh Domain of Hif-1 Failed to Inhibit the Hif-1 Transcriptional Activity in Hypoxia, Biological Research (2020)
27. A Truncated Snail1 Transcription Factor Alters the Expression of Essential Emt Markers and Suppresses Tumor Cell Migration in a Human Lung Cancer Cell Line, Recent Patents on Anti-Cancer Drug Discovery (2019)
28. Cea Plasmid As Therapeutic Dna Vaccination Against Colorectal Cancer, Iranian Journal of Immunology (2019)
29. Design and Evaluation of a Hypoallergenic Peptide-Based Vaccine for Salsola Kali Allergy, International Immunopharmacology (2019)
30. Effects of Influenza Derived Peptide on Cd8 T Cell Responses to Mhc Class I-Restricted Human Telomerase Reverse Transcriptase (Htert)-Derived Peptide, International Journal of Peptide Research and Therapeutics (2019)
31. Functional Deimmunization of Interferon Beta-1B by Identifying and Silencing Human T Cells Epitopes, Iranian Journal of Allergy# Asthma and Immunology (2019)
32. Ige-Mediated Allergic Responses Associated to Ailanthus Altissima Pollen Using an Animal Model, Allergologia et Immunopathologia (2019)
33. Optimization and Comparison of Different Methods and Factors for Efficient Transformation of Brucella Abortus Rb51strain, Advanced Biomedical Research (2019)
34. Optimization and Comparison of Different Methods and Factors for Efficient Transformation of Brucella Abortus Rb51strain, Advanced Biomedical Research (2019)
35. Post-Infarct Morphine Treatment Mitigates Left Ventricular Remodeling and Dysfunction in a Rat Model of Ischemia-Reperfusion, European Journal of Pharmacology (2019)
36. Acute Sleep Deprivation Induces Cardioprotection Against Ischemia/Reperfusion Injury Through Reducing Inflammatory Responses: The Role of Central Gaba-A Receptors, General Physiology and Biophysics (2018)
37. Computational Analysis of Specific Ige Epitopes Responsible for Allergy to Fish, Current Immunology Reviews (2018)
38. Construction of a Recombinant B-Cell Epitope Vaccine Based on a Der P1-Derived Hypoallergen: A Bioinformatics Approach, Immunotherapy (2018)
39. Functions of the Heterologous Intron-Derived Fragments Intra and Extra Factor Ix-Cdna Coding Region on the Human Factor Ix Expression in Hepg2 and Hek-293T Cells, Iranian Journal of Biotechnology (2018)
40. Novel Report of the Phytochemical Composition From Fraxinus Excelsior Pollen Grains, Journal of Applied Botany and Food Quality (2018)
41. Decorating and Loading Ghosts With Allergens for Allergen Immunotherapy, Human Vaccines and Immunotherapeutics (2017)
42. Effects of Viral Peptide Presentation on Cd4+ T Cell Responses to Mhc Class Ii-Restricted Tumor Peptides, International Journal of Cancer Management (2017)
43. Evaluation of an Albumin-Binding Domain Protein Fused to Recombinant Human Il-2 and Its Effects on the Bioactivity and Serum Half-Life of the Cytokine, Iranian Biomedical Journal (2017)
44. Exhaustion of T Lymphocytes in the Tumor Microenvironment: Significance and Effective Mechanisms, Cellular Immunology (2017)
45. Expression of Recombinant Parvalbumin From Wolf-Herring Fish and Determination of Its Ige-Binding Capability, Food and Agricultural Immunology (2017)
46. Peptide-Based Vaccines Derived From Fceri Beta Subunit Can Reduce Allergic Response in Mice Model, Iranian Journal of Allergy# Asthma and Immunology (2017)
47. The Effect of Licorice Protein Fractions on Proliferation and Apoptosis of Gastrointestinal Cancer Cell Lines, Nutrition and Cancer (2017)
48. The Effect of Licorice Protein Fractions on Proliferation and Apoptosis of Gastrointestinal Cancer Cell Lines, Nutrition and Cancer (2017)
49. Corrigendum to Inducible Expression of Indoleamine 2,3-Dioxygenase Attenuates Acute Rejection of Tissue-Engineered Lung Allografts in Rats [Gene 576/1P3 (2015) 412-420], Gene (2016)
50. Evaluation of the Functionality of 4T1 Cell Line in Development of Metastatic Cancer in Balb/C Mice As an Animal Model, Journal of Isfahan Medical School (2016)
51. Evaluation of the Functionality of 4T1 Cell Line in Development of Metastatic Cancer in Balb/C Mice As an Animal Model, Journal of Isfahan Medical School (2016)
52. Identification and Characterization of Main Allergic Proteins in Cooked Wolf Herring Fish, Iranian Journal of Allergy# Asthma and Immunology (2016)
53. Inducible Expression of Indoleamine 2,3-Dioxygenase Attenuates Acute Rejection of Tissue-Engineered Lung Allografts in Rats, Gene (2016)
54. Localization of Immunodominant Epitopes Within the “A” Determinant of Hepatitis B Surface Antigen Using Monoclonal Antibodies, Archives of Virology (2016)
55. Pollinosis to Tree of Heaven (Ailanthus Altissima) and Detection of Allergenic Proteins: A Case Report, Annals of Allergy# Asthma and Immunology (2016)
56. The Prevalence of Selective Immunoglobulin M Deficiency (Sigmd) in Iranian Volunteer Blood Donors, Human Immunology (2016)
57. The Effect of Il-22 and Il-28 in Induction of Type 1 Regulatory T (Tr1) Cells, Iranian Journal of Allergy# Asthma and Immunology (2015)
58. The Induction of Metformin Inhibitory Effects on Tumor Cell Growth in Hypoxic Condition, Iranian Journal of Allergy# Asthma and Immunology (2015)
59. The Effect of Protein Extract of Licorice Root in Proliferation of Ht-29 and Ct26 Cancer Cell Lines, Journal of Isfahan Medical School (2014)