Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Biology-Oriented Drug Synthesis (Biods) Approach Towards Synthesis of Ciprofloxacin-Dithiocarbamate Hybrids and Their Antibacterial Potential Both in Vitro and in Silico
Ahmadreza Shahverdi
Ahmadreza Shahverdi

Professor of Pharmaceutical Biotechnology

Department Pharmaceutical Biotechnology

School of Pharmacy

Biotechnology Research Center

Tehran University of Medical Sciences

All Documents
1. A Novel Broad-Spectrum Bacteriophage Cocktail Against Methicillin-Resistant Staphylococcus Aureus: Isolation, Characterization, and Therapeutic Potential in a Mastitis Mouse Model, PLoS ONE (2025)
2. A Novel Halophilic Laccase From Halomonas Elongata: Purification, Characterization, and Application in Green Synthesis of Salicylic Acid, International Journal of Biological Macromolecules (2025)
3. Cost-Reduction Strategy to Culture Patient Derived Bladder Tumor Organoids, Scientific Reports (2025)
4. Decoding Shared Molecular Mechanisms of Sars-Cov-2 and Hcov-Oc43 in Covid-19 Neurological Manifestations: A Systems Biology Approach, Gene Reports (2025)
5. Enhanced Laccase Production by Paramyrothecium Roridum Under Solid-State Fermentation: Application in Neutral-Ph Delignification and Valorization of Acorn Shells, International Journal of Biological Macromolecules (2025)
6. In the Pursuit of an Efficient Delignification From Pumpkin Seed Shells by the Polyextremophilic and Laccase-Producing Bacterial Isolate Halomonas Elongata, Biomass Conversion and Biorefinery (2025)
7. Investigating Molecular Aspects of Sars-Cov-2 Neurological Manifestations, a Systems Biology Approach, Human Gene (2025)
8. Photo-Mediated Biological Preparation of Silver Nanoparticles Paste in an Organic Solvent System: Formulation and Antimicrobial Studies, Applied Physics A: Materials Science and Processing (2025)
9. Ascorbic Acid and Α-Tocopherol in the Inactivated Sars-Cov-2 Vaccine Formulation: Induction of the Th1 Pattern in Aged Mice, Viral Immunology (2024)
10. Characterization and Genome Analysis of a Broad Host Range Lytic Phage Vb_Sens_Tums_E19 Against Salmonella Enterica and Its Efficiency Evaluation in the Liquid Egg, Canadian Journal of Microbiology (2024)
11. Decoding the Structure–Function Relationship of the Muramidase Domain in E. Coli O157.H7 Bacteriophage Endolysin: A Potential Building Block for Chimeric Enzybiotics, Protein Journal (2024)
12. Enzymatic Dual-Faced Janus Structures Based on the Hierarchical Organic-Inorganic Hybrid Matrix for an Effective Bioremoval and Detoxification of Reactive Blue-19, International Journal of Biological Macromolecules (2024)
13. Evaluating the Effectiveness and Safety of a Novel Phage Cocktail As a Biocontrol of Salmonella in Biofilm, Food Products, and Broiler Chicken, Frontiers in Microbiology (2024)
14. Exploring the Nutritional Benefits of Acorns: Phytochemical Profiles and Biological Activity, Annals of the University Dunarea de Jos of Galati, Fascicle VI: Food Technology (2024)
15. Generation of Murine Chimeric Antigen Receptor-Modified T Cells for in Vivo Studies in Syngeneic Tumor Models, Current Protocols (2024)
16. Isolation, Characterization, and Genome Analysis of a Broad Host Range Salmonella Phage Vb_Sens_Tums_E4: A Candidate Bacteriophage for Biocontrol, Veterinary Research Communications (2023)
17. Isolation, Characterization, and Genomic Analysis of Vb_Paep_Tums_P121, a New Lytic Bacteriophage Infecting Pseudomonas Aeruginosa, Archives of Virology (2023)
18. Isolation, Characterization, and Genomic Analysis of Vb_Paes_Tums_P81, a Lytic Bacteriophage Against Pseudomonas Aeruginosa, Virus Genes (2023)
19. Selenium Nanoparticle-Enriched Lactobacillus Plantarum Causes More Anti-Carcinogenic Effect on Human Colon Cancer Cells Compared to Non-Enriched Ones, BioNanoScience (2023)
20. The Cytotoxicity of Tellurium Nanoparticles on Different Cell Lines and Their in Vivo Anticancer Effects in an Animal Model, Middle East Journal of Cancer (2023)
21. Green Synthesis of Selenium Nanoparticles in the Presence of Mycobacterium Bovis Cell Lysate: A Novel Fabrication Approachand Its Immune-Modulatory Effects, Nano Biomedicine and Engineering (2022)
22. Green Synthesis, Characterization, and Biological Evaluation of Hydroxyl-Capped Tellurium Nanoparticles, Journal of Sciences# Islamic Republic of Iran (2022)
23. Photo-Mediated Preparation of Silver Nanoparticles Dry Concentrate in an Organic Solvent System, Using Culture Supernatant of Klebsiella Pneumonia: A Preliminary Study, Journal of Sciences# Islamic Republic of Iran (2022)
24. Potentiation of the Therapeutic Effect of Intravesical Bcg Through Synthetic and Biogenic Selenium Nanoparticles in a Nitrosamine-Induced Bladder Cancer Mouse Model, Advances in Cancer Biology - Metastasis (2022)
25. Wound Healing and Anti-Inflammatory Effects of Bacterial Cellulose Coated With Pistacia Atlantica Fruit Oil, DARU# Journal of Pharmaceutical Sciences (2022)
26. Comparison of Cytokine Expression in Human Pbmcs Stimulated With Normal and Heat-Shocked Lactobacillus Plantarum Cell Lysate, Probiotics and Antimicrobial Proteins (2021)
27. Corrigendum: Process-Dependent Photocatalytic Performance of Quantum Sized Zno Nanoparticles (Mater. Res. Express (2018) 5 (115027) Doi: 10.1088/2053-1591/Aadce9), Materials Research Express (2021)
28. Fabrication of Calcium Sulfate Coated Selenium Nanoparticles and Corresponding In-Vitro Cytotoxicity Effects Against 4T1 Breast Cancer Cell Line, Avicenna Journal of Medical Biotechnology (2021)
29. Research Paper: The Toxicity of Synthetic and Biogenic Selenium Nanoparticles on Human Brain Glioblastoma Cellline:Aninvitrocomparison, International Journal of Medical Toxicology and Forensic Medicine (2020)
30. Periovax3, a Key Antigenic Determinant With Immunoprotective Potential Against Periodontal Pathogen, Microbial Pathogenesis (2019)
31. Biosynthesis of Senps by Mycobacterium Bovis and Their Enhancing Effect on the Immune Response Against Hbs Antigens: An in Vivo Study, IET Nanobiotechnology (2018)
32. Characterization of Folic Acid Surface-Coated Selenium Nanoparticles and Corresponding in Vitro and in Vivo Effects Against Breast Cancer, Archives of Medical Research (2018)
33. Process-Dependent Photocatalytic Performance of Quantum Sized Zno Nanoparticles, Materials Research Express (2018)
34. Antimicrobial Effect of Some Medicinal Smoke, Iranian Traditional Medicine, Journal of Medicinal Plants (2017)
35. In Vitro Activity of Two Nanoparticles on Clinical Isolates of Candida Parapsilosis, Showing Resistance Against Antifungal Agents in Children, Archives of Clinical Infectious Diseases (2017)
36. In Vitro Activity of Two Nanoparticles on Clinical Isolates of Candida Parapsilosis, Showing Resistance Against Antifungal Agents in Children, Archives of Clinical Infectious Diseases (2017)
37. Isolation, One-Step Affinity Purification, and Characterization of a Polyextremotolerant Laccase From the Halophilic Bacterium Aquisalibacillus Elongatus and Its Application in the Delignification of Sugar Beet Pulp, Bioresource Technology (2017)
38. Oral Administration of Synthetic Selenium Nanoparticles Induced Robust Th1 Cytokine Pattern After Hbs Antigen Vaccination in Mouse Model, Journal of Infection and Public Health (2017)
39. Polyacrylamide/Reduced Graphene Oxide-Ag Nanocomposite As Highly Efficient Antibacterial Transparent Film, Journal of the Iranian Chemical Society (2017)
40. Targeted Intracellular Heat Transfer in Cancer Therapy: Assessment of Asparagine-Laminated Gold Nanoparticles in Cell Model of T Cell Leukemia, Iranian Journal of Public Health (2017)
41. The Determination of Biomass/Selenium Ratio and the Impact of Glucose and Piperitone Upon Selenium Ion Reduction Using Bacillus Sp. Msh-1 Whole Cells, Nano Biomedicine and Engineering (2017)
42. Tracing Tellurium and Its Nanostructures in Biology, Biological Trace Element Research (2017)
43. Blockage of Both the Extrinsic and Intrinsic Pathways of Diazinon-Induced Apoptosis in Patu Cells by Magnesium Oxide and Selenium Nanoparticles, International Journal of Nanomedicine (2016)
44. Enhancing Activity and Thermostability of Lipase a From Serratia Marcescens by Site-Directed Mutagenesis, Enzyme and Microbial Technology (2016)
45. Metal, Metalloid, and Oxide Nanoparticles for Therapeutic and Diagnostic Oncology, Nano Biomedicine and Engineering (2016)
46. Adjuvant Effect of Biogenic Selenium Nanoparticles Improves the Immune Responses and Survival of Mice Receiving 4T1 Cell Antigens As Vaccine in Breast Cancer Murine Model, Journal of Nanoscience and Nanotechnology (2015)
47. Antimicrobial Activities of Three Medicinal Plants and Investigation of Flavonoids of Tripleurospermum Disciforme, Iranian Journal of Pharmaceutical Research (2015)
48. Bacterial Expression and Characterization of an Active Recombinant Lipase a From Serratia Marcescens With Truncated C-Terminal Region, Journal of Molecular Catalysis B: Enzymatic (2015)
49. Biosynthesis of Tellurium Nanoparticles by Lactobacillus Plantarum and the Effect of Nanoparticle-Enriched Probiotics on the Lipid Profiles of Mice, IET Nanobiotechnology (2015)
50. Comparison of Difference Between Fluconazole and Silver Nanoparticles in Antimicrobial Effect on Fluconazole-Resistant Candida Albicans Strains, Archives of Pediatric Infectious Diseases (2015)
51. Dose-Response Relationship Study of Selenium Nanoparticles As an Immunostimulatory Agent in Cancer-Bearing Mice, Archives of Medical Research (2015)
52. Investigation for Antimicrobial Resistance-Modulating Activity of Diethyl Malate and 1-Methyl Malate Against Beta-Lactamase Class a From Bacillus Licheniformis by Molecular Dynamics, in Vitro and in Vivo Studies, Journal of Biomolecular Structure and Dynamics (2015)
53. Monoterpenes As Nitrofurantoin Resistance Modulating Agents: Minimal Structural Requirements, Molecular Dynamics Simulations, and the Effect of Piperitone on the Emergence of Nitrofurantoin Resistance in Enterobacteriaceae, Journal of Molecular Modeling (2015)
54. Th1 Immune Response Induction by Biogenic Selenium Nanoparticles in Mice With Breast Cancer: Preliminary Vaccine Model, Iranian Journal of Biotechnology (2015)
55. The Antimicrobial Effects and Metabolomic Footprinting of Carboxyl-Capped Bismuth Nanoparticles Against Helicobacter Pylori, Applied Biochemistry and Biotechnology (2014)
56. Biosynthesis of Bismuth Nanoparticles Using Serratia Marcescens Isolated From the Caspian Sea and Their Characterisation, IET Nanobiotechnology (2012)