Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Expression of Mirnas Targeting Mtor and S6k1 Genes of Mtor Signaling Pathway Including Mir-96, Mir-557, and Mir-3182 in Triple-Negative Breast Cancer
Malihe Paknejad
Malihe Paknejad

Professor of Biochemistry

Department Biochemistry

School of Medicine

Tehran University of Medical Sciences

All Documents
1. A Double-Edged Sword Effect of Silver Nanoparticles on Angiogenesis in 4T1 Breast Cancer-Bearing Mice, Naunyn-Schmiedeberg's Archives of Pharmacology (2025)
2. Metabolically Healthy/Unhealthy Obesity and Breast Cancer: A Possible Role of Plasma-Derived Extracellular Vesicles on the Cancerous Behavior of Triple-Negative Breast Cancer, Biochemical and Biophysical Research Communications (2024)
3. The Obeticholic Acid Can Positively Regulate the Cancerous Behavior of Mcf7 Breast Cancer Cell Line, Molecular Biology Reports (2024)
4. Apoptotic Effects of Human Amniotic Fluid Mesenchymal Stem Cells Conditioned Medium on Human Mcf-7 Breast Cancer Cell Line, BioImpacts (2023)
5. Exosomes Isolated From Metabolically Unhealthy Normal Weight and Overweight Phenotypes Deteriorate the Er/Pr Positive Breast Cancer Behavior, Journal of Diabetes and Metabolic Disorders (2023)
6. Preparation and Preclinical Characterization of 111 In-Dtpa-Anti-Muc1 As a Radioimmunoconjugate for Diagnosis of Breast Cancer by Single-Photon Emission Computed Tomography, Journal of Cancer Research and Therapeutics (2022)
7. A Theoretical Strategy for Acceleration of Human Immune Response Against Sars-Cov-2: A Fusion Protein Harboring Virus-Binding and Pre-Exposed Antigen Domains, VirusDisease (2021)
8. Anti-Inflammatory Effects of Plasma Circulating Exosomes Obtained From Normal-Weight and Obese Subjects on Hepatocytes, Endocrine# Metabolic and Immune Disorders - Drug Targets (2021)
9. Evaluating the Effect of a Mixture of Two Main Conjugated Linoleic Acid Isomers on Hepatic Steatosis in Hepg2 Cellular Model, Molecular Biology Reports (2021)
10. Paper Based Analytical Devices for Blood Grouping: A Comprehensive Review, Biomedical Microdevices (2021)
11. Positive Correlation Between Circulating Fetuin-A and Severity of Coronary Artery Disease in Men, Endocrine# Metabolic and Immune Disorders - Drug Targets (2021)
12. Preparation, Quality Control, and Biodistribution Assessment of [111In]In-Dota-Pr81 in Balb/C Mice Bearing Breast Tumors, Journal of Labelled Compounds and Radiopharmaceuticals (2021)
13. Vitamin D Represses the Aggressive Potential of Osteosarcoma, Endocrine# Metabolic and Immune Disorders - Drug Targets (2021)
14. Close Relationship Between Diabetes and Cancer, Iranian Journal of Public Health (2020)
15. Effect of Circulating Exosomes Derived From Normal-Weight and Obese Women on Gluconeogenesis, Glycogenesis, Lipogenesis and Secretion of Fgf21 and Fetuin a in Hepg2 Cells, Diabetology and Metabolic Syndrome (2020)
16. Influence of Plasma Circulating Exosomes Obtained From Obese Women on Tumorigenesis and Tamoxifen Resistance in Mcf-7 Cells, IUBMB Life (2020)
17. Mir-135B Induces Osteosarcoma Invasion by the Modulation of Foxo-1 and C-Myc, International Journal of Cancer Management (2020)
18. Specific Cellular Internalization and Ph-Responsive Behavior of Doxorubicin Loaded Plga-Peg Nanoparticles Targeted With Anti Egfrviii Antibody, Life Sciences (2020)
19. The Possible Effect of Silver Nanoparticles on Glyceraldehyde-3-Phosphate Dehydrogenase Activity and Formation of Amyloid-Like Aggregates in Mcf-7 Cell Line, IUBMB Life (2020)
20. A Critical Challenge in the Development of Antibody: Selecting the Appropriate Fragment of the Target Protein As an Antigen Based on Various Epitopes or Similar Structure, Molecular Immunology (2019)
21. The Influence of Psychological Stress on the Initiation and Progression of Diabetes and Cancer, International Journal of Endocrinology and Metabolism (2019)
22. Effects of Led-Based Photodynamic Therapy Using Red and Blue Lights, With Natural Hydrophobic Photosensitizers on Human Glioma Cell Line, Photodiagnosis and Photodynamic Therapy (2018)
23. Evaluation of Targeted Curcumin (Cur) Loaded Plga Nanoparticles for in Vitro Photodynamic Therapy on Human Glioblastoma Cell Line, Photodiagnosis and Photodynamic Therapy (2018)
24. Expression of Mirnas Targeting Mtor and S6k1 Genes of Mtor Signaling Pathway Including Mir-96, Mir-557, and Mir-3182 in Triple-Negative Breast Cancer, Applied Biochemistry and Biotechnology (2018)
25. Production and Characterization of Monoclonal and Polyclonal Antibodies Against Truncated Recombinant Dickkopf-1 As a Candidate Biomarker, Monoclonal Antibodies in Immunodiagnosis and Immunotherapy (2018)
26. Targeted Delivery of Doxorubicin Into Tumor Cells by Nanostructured Lipid Carriers Conjugated to Anti-Egfrviii Monoclonal Antibody, Artificial Cells# Nanomedicine and Biotechnology (2018)
27. Toxicity of Silver Nanoparticles on Different Tissues of Balb/C Mice, Life Sciences (2018)
28. Development of Doxorubicin-Loaded Nanostructured Lipid Carriers: Preparation, Characterization, and in Vitro Evaluation on Mcf-7 Cell Line, BioNanoScience (2017)
29. Mzd7349 Peptide-Conjugated Plga Nanoparticles Directed Against Vcam-1 for Targeted Delivery of Simvastatin to Restore Dysfunctional Huvecs, Microvascular Research (2017)
30. Development of [64Cu]-Dota-Pr81 Radioimmunoconjugate for Muc-1 Positive Pet Imaging, Nuclear Medicine and Biology (2016)
31. Potential of Mzd7349-Conjugated Plga Nanoparticles for Selective Targeting of Vascular Cell-Adhesion Molecule-1 in Inflamed Endothelium, Microvascular Research (2016)
32. Preparation, Optimization, and Characterization of Simvastatin Nanoparticles by Electrospraying: An Artificial Neural Networks Study, Journal of Applied Polymer Science (2016)
33. Analytical Characterization of Label-Free Immunosensor Subsystems Based on Multi-Walled Carbon Nanotube Array-Modified Gold Interface, Combinatorial Chemistry and High Throughput Screening (2015)
34. Characteristics of 26 Kda Antigen of H.Pylori by Monoclonal Antibody, Iranian Journal of Allergy# Asthma and Immunology (2015)
35. Preparation and Characterization of a Monoclonal Antibody Against Morphine, Monoclonal Antibodies in Immunodiagnosis and Immunotherapy (2015)