Tehran University of Medical Sciences

Science Communicator Platform

Faculty Members have conducted research related to the Transgenerational Effects of Parental Morphine Withdrawal on Learning and Spatial Memory Processes and Hippocampal Bdnf Protein Levels Across Two Generations of Male Rats; [Bdnf اثرات بی ننسلی ترک مورفین والدینی بر فرآیندهای یادگیری و حافظه فضایی و سطوح پروتئینهیپوکامپ در دو نسل از مو شهای صحرایی نر]
Nasim Vousooghi
Nasim Vousooghi

Associate Professor of Pharmacology

Department Tissue Engineering and Applied Cellular Sciences

School of Advanced Technologies in Medicine

Research Center for Cognitive and Behavioral Sciences

Tehran University of Medical Sciences

All Documents
1. Effect of Testosterone on Maintenance of Morphine-Induced Conditioned Place Preference: Androgen and M-Opioid Receptor Gene Expressions in Pfc and Nac of Rats, Clinical Psychopharmacology and Neuroscience (2026)
2. Immunometabolism Crosstalk Between Regulatory T Cells and Glucose Homeostasis of Type 1 Diabetes, Clinical and Experimental Immunology (2026)
3. Personalized Immunotherapy in Hcc: Synthesis, Delivery, and Clinical Progress of Mrna-Based Vaccines, Cancer Cell International (2026)
4. Targeting Ischemic Stroke With Neural Stem Cells: Insights Into Endogenous Repair Mechanisms, Biomaterial-Based Delivery, and Exosome Therapies, Molecular Neurobiology (2026)
5. Gamma Delta T Cells in the Tumour Microenvironment: A Double-Edged Sword, Immunology (2025)
6. Investigating the Dimensions of Quality of Life, Depression, Anxiety, Stress, and Substance Craving in People With Opioid Use Disorders, Methadone-Maintained Subjects, and Narcotics Anonymous Members, Basic and Clinical Neuroscience (2025)
7. Natural Killer Cell Therapy in Hepatocellular Carcinoma: A Comprehensive Review, Discover Oncology (2025)
8. Natural Killer Cells As Critical Modulators of Heart Disease: Exploring Pathophysiological Mechanisms and Therapeutic Perspectives, Iranian journal of allergy, asthma, and immunology (2025)
9. Safety and Feasibility of Blockade of Nk Group-2 Member-A Receptor in Natural Killer Cells Combined With Cetuximab Antibody in Patients With Advanced Gastric Adenocarcinoma, Advanced Pharmaceutical Bulletin (2025)
10. Safety and Feasibility of Blockade of Nk Group-2 Member-A Receptor in Natural Killer Cells Combined With Cetuximab Antibody in Patients With Advanced Gastric Adenocarcinoma, Advanced Pharmaceutical Bulletin (2025)
11. Association of Abcb1, Μ-Opioid Receptor, and Cytochrome P450 Genes With Methadone Dose in Iranian Male Addicts Under Methadone Therapy, Basic and Clinical Neuroscience (2024)
12. Autophagy Genes and Signaling Pathways in Endometrial Decidualization and Pregnancy Complications, Journal of Reproductive Immunology (2024)
13. Cell Therapy Using Anti-Nkg2a Pretreated Natural Killer Cells in Patients With Hepatocellular Carcinoma, Advanced Pharmaceutical Bulletin (2024)
14. Comparing the Efficacy of Matrix Therapy, Transcranial Magnetic Stimulation, and Cognitive Rehabilitation in Attention Bias Modification and Craving Reduction in Stimulant Drug Users, Basic and Clinical Neuroscience (2024)
15. Synthesis and in Silico Admet Evaluation of New Thiazole and Thiazolidine-4-One Derivatives As Non-Ulcerogenic Analgesic and Anti-Inflammatory Agents, Journal of the Serbian Chemical Society (2024)
16. The Effect of Morphine Administration on Glun3b Nmda Receptor Subunit Mrna Expression in Rat Brain, Acta neurobiologiae experimentalis (2024)
17. The Effectiveness of Universal Educational Interventions for Prevention of Illicit Drug Use Among University Students: A Systematic Review, Iranian Journal of Public Health (2024)
18. Therapeutic Potential of Placenta-Derived Stem Cells Cultivated on Noggin-Loaded Nanochitosan/Polypyrrole-Alginate Conductive Scaffold to Restore Spinal Cord Injury, Stem Cell Research and Therapy (2024)
19. A Comprehensive View on the Quercetin Impact on Bladder Cancer: Focusing on Oxidative Stress, Cellular, and Molecular Mechanisms, Fundamental and Clinical Pharmacology (2023)
20. Evaluation of the Effect of Mesenchymal Stem Cells Injection in the Nucleus Accumbens on the Morphine Reinstatement Behavior in a Conditioned Place Preference Model in Wistar Rat: Expression Changes of Nmda Receptor Subunits and Nt-3, Behavioural Brain Research (2023)
21. Exosomes Released From U87 Glioma Cells Treated With Curcumin And/Or Temozolomide Produce Apoptosis in Naive U87 Cells, Pathology Research and Practice (2023)
22. Pre-Mating Administration of Theophylline Could Prevent the Transgenerational Effects of Maternal Morphine Dependence on Offspring Anxiety Behavior: The Role of Dopamine Receptors, Pharmacology Biochemistry and Behavior (2023)
23. Psychometric Characteristics of the Persian Version of the Opiate Dosage Adequacy Scale (Odas), Basic and Clinical Neuroscience (2023)
24. Recent Advances in Mesenchymal Stem/Stromal Cells (Mscs)-Based Approaches for Osteoarthritis (Oa) Therapy, Cell Biology International (2023)
25. Effects of Placenta-Derived Human Amniotic Epithelial Cells on the Wound Healing Process and Tgf-Β Induced Scar Formation in Murine Ischemic-Reperfusion Injury Model, Stem Cell Reviews and Reports (2022)
26. Microfluidics for Detection of Exosomes and Micrornas in Cancer: State of the Art, Molecular Therapy Nucleic Acids (2022)
27. Potential Biomarkers of Addiction Identified by Real-Time Pcr in Human Peripheral Blood Lymphocytes: A Narrative Review, Biomarkers in Medicine (2022)
28. Association of Shank3 Gene Polymorphism and Parkinson Disease in the North of Iran, Basic and Clinical Neuroscience (2021)
29. Comparing Sexual Function Between Opioid Dependents Consuming Methadone or Opium Tincture, Iranian Journal of Psychiatry (2021)
30. Systemic Administration of N-Acetylcysteine During the Extinction Period and on the Reinstatement Day Decreased the Maintenance of Morphine Rewarding Properties in the Rats, Behavioural Brain Research (2021)
31. Catechol-O-Methyltransferase Gene Expression in Stress-Induced and Non-Stress Induced Schizophrenia, Psychiatric Genetics (2020)
32. Evaluation of the Relationship Between the Gene Expression Level of Orexin-1 Receptor in the Rat Blood and Prefrontal Cortex, Novelty-Seeking, and Proneness to Methamphetamine Dependence: A Candidate Biomarker, Peptides (2020)
33. Oxytocin Blocks Opioid Withdrawal Symptoms Only When Combined With Group Therapy: A Double-Blind, Randomized Controlled Clinical Trial, Iranian Journal of Psychiatry and Behavioral Sciences (2020)
34. Role of Modafinil in the Treatment of Patients With Methamphetamine Dependence; an Update on Randomized, Controlled Clinical Trial, Tropical Journal of Pharmaceutical Research (2020)
35. The Effect of Lactobacillus Casei Consumption in Improvement of Obsessive–Compulsive Disorder: An Animal Study, Probiotics and Antimicrobial Proteins (2020)
36. The Effect of Microinjection of Cart 55-102 Into the Nucleus Accumbens Shell on Morphine-Induced Conditioned Place Preference in Rats: Involvement of the Nmda Receptor, Peptides (2020)
37. Benefit Effect of Rem-Sleep Deprivation on Memory Impairment Induced by Intensive Exercise in Male Wistar Rats: With Respect to Hippocampal Bdnf and Trkb, Nature and Science of Sleep (2019)
38. Corrigendum to “Evaluation of the Cart Peptide Expression in Morphine Sensitization in Male Rats” (European Journal of Pharmacology (2017) 802 (52–59), (S0014299917301164) (10.1016/J.Ejphar.2017.02.040)), European Journal of Pharmacology (2019)
39. Evaluation of Dynorphin and Kappa-Opioid Receptor Level in the Human Blood Lymphocytes and Plasma: Possible Role As a Biomarker in Severe Opioid Use Disorder, Drug and Alcohol Dependence (2019)
40. Heroin-Based Crack Induces Hyperalgesia Through Β-Arrestin 2 Redistribution and Phosphorylation of Erk1/2 and Jnk in the Periaqueductal Gray Area, Neuroscience Letters (2019)
41. Morphine Exposure and Enhanced Depression-Like Behaviour Confronting Chronic Stress in Adult Male Offspring Rat, Basic and Clinical Neuroscience (2019)
42. Nmda Receptor Subunits Change in the Prefrontal Cortex of Pure-Opioid and Multi-Drug Abusers: A Post-Mortem Study, European Archives of Psychiatry and Clinical Neuroscience (2019)
43. Nmda Receptors of Blood Lymphocytes Anticipate Cognitive Performance Variations in Healthy Volunteers, Physiology and Behavior (2019)
44. Parental Morphine Exposure Enhances Morphine (But Not Methamphetamine) Preference and Increases Monoamine Oxidase-B Level in the Nucleus Accumbens, Behavioural Pharmacology (2019)
45. Rolipram Optimizes Therapeutic Effect of Bevacizumab by Enhancing Proapoptotic, Antiproliferative Signals in a Glioblastoma Heterotopic Model, Life Sciences (2019)
46. The Role of Kinase Signaling in Resistance to Bevacizumab Therapy for Glioblastoma Multiforme, Cancer Biotherapy and Radiopharmaceuticals (2019)
47. Transplantation of Adipose Tissue-Derived Stem Cells Into Brain Through Cerebrospinal Fluid in Rat Models: Protocol Development and Initial Outcome Data, Current Stem Cell Research and Therapy (2019)
48. Adult Rat Morphine Exposure Changes Morphine Preference, Anxiety, and the Brain Expression of Dopamine Receptors in Male Offspring, International Journal of Developmental Neuroscience (2018)
49. Alteration of Dopamine Receptors Subtypes in the Brain of Opioid Abusers: A Postmortem Study in Iran, Neuroscience Letters (2018)
50. Corrigendum to “A New Rat Model of Neonatal Bilirubin Encephalopathy (Kernicterus)” [J. Pharmacol. Toxicol. Methods 84 (2017) 44–50] (S105687191630123x) (10.1016/J.Vascn.2016.10.002)), Journal of Pharmacological and Toxicological Methods (2018)
51. Effect of Rat Parental Morphine Exposure on Passive Avoidance Memory and Morphine Conditioned Place Preference in Male Offspring, Physiology and Behavior (2018)
52. Executive Functions Are Related to Serum Testosterone and Basal Metabolism Rate Fluctuation But Not Lymphocyte Dopamine Receptor Expression in the Young Healthy Participants, Physiology and Pharmacology (Iran) (2018)
53. Expression of Nmda Receptor Subunits in Human Blood Lymphocytes: A Peripheral Biomarker in Online Computer Game Addiction, Journal of Behavioral Addictions (2018)
54. Is the Nociception Mechanism Altered in Offspring of Morphine-Abstinent Rats?, Journal of Pain (2018)
55. Plasticity After Pediatric Cochlear Implantation: Implication From Changes in Peripheral Plasma Level of Bdnf and Auditory Nerve Responses, International Journal of Pediatric Otorhinolaryngology (2018)
56. A New Rat Model of Neonatal Bilirubin Encephalopathy (Kernicterus), Journal of Pharmacological and Toxicological Methods (2017)
57. Evaluation of Plasma Sphingosine 1-Phosphate, Hepcidin and Cardiovascular Damage Biomarkers (Cardiac Troponin I and Homocysteine) in Rats Infected With Brucellosis and Vaccinated (Rev-1, Rb-51), Microbial Pathogenesis (2017)
58. Evaluation of the Cart Peptide Expression in Morphine Sensitization in Male Rats, European Journal of Pharmacology (2017)
59. Mitochondrial Impairments Contribute to Spatial Learning and Memory Dysfunction Induced by Chronic Tramadol Administration in Rat: Protective Effect of Physical Exercise, Progress in Neuro-Psychopharmacology and Biological Psychiatry (2017)
60. Perifosine Enhances Bevacizumab-Induced Apoptosis and Therapeutic Efficacy by Targeting Pi3k/Akt Pathway in a Glioblastoma Heterotopic Model, Apoptosis (2017)
61. Rolipram Potentiates Bevacizumab-Induced Cell Death in Human Glioblastoma Stem-Like Cells, Life Sciences (2017)
62. The Role of Protein Kinase B Signaling Pathway in Anti-Cancer Effect of Rolipram on Glioblastoma Multiforme: An in Vitro Study, Basic and Clinical Neuroscience (2017)
63. Cart Peptide and Opioid Addiction: Expression Changes in Male Rat Brain, Neuroscience (2016)
64. Dorsal Hippocampal Nmda Receptors Mediate the Interactive Effects of Arachidonylcyclopropylamide and Mdma/Ecstasy on Memory Retrieval in Rats, Progress in Neuro-Psychopharmacology and Biological Psychiatry (2016)
65. Effect of Circadian Rhythm Disturbance on Morphine Preference and Addiction in Male Rats: Involvement of Period Genes and Dopamine D1 Receptor, Neuroscience (2016)
66. Efficacy of Human Adipose Tissue-Derived Stem Cells on Neonatal Bilirubin Encephalopathy in Rats, Neurotoxicity Research (2016)
67. Evaluation of Cart Peptide Level in Rat Plasma and Csf: Possible Role As a Biomarker in Opioid Addiction, Peptides (2016)
68. Effect of Multiple Intraperitoneal Injections of Human Bone Marrow Mesenchymal Stem Cells on Cuprizone Model of Multiple Sclerosis, Iranian Biomedical Journal (2015)
69. Mrna Expression of Dopamine Receptors in Peripheral Blood Lymphocytes of Computer Game Addicts, Journal of Neural Transmission (2015)
70. X Chromosome Inactivation in Opioid Addicted Women, Basic and Clinical Neuroscience (2015)